Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thomas Trolle"'
Autor:
Nadia Viborg, Michail Angelos Pavlidis, Marina Barrio-Calvo, Stine Friis, Thomas Trolle, Anders Bundgaard Sørensen, Christian Bahne Thygesen, Søren Vester Kofoed, Daniela Kleine-Kohlbrecher, Sine Reker Hadrup, Birgitte Rønø
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Recent findings have positioned tumor mutation-derived neoepitopes as attractive targets for cancer immunotherapy. Cancer vaccines that deliver neoepitopes via various vaccine formulations have demonstrated promising preliminary results in p
Externí odkaz:
https://doaj.org/article/018569528672479ca528c27630e5b5be
Autor:
Anders Jespersen, Daniela Kleine-Kohlbrecher, Nadia Viborg, Mads Lausen, Thomas Trolle, Michail A Pavlidis, Nikolas H Thuesen, Christian Garde, Thomas S Jepsen, Britt W Lauenborg, Birgitte Rønø
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/fc2dbb6a266c43c58f3b25912d31d8f3
Autor:
Paolo A Ascierto, Georgina V Long, Michael Chisamore, Paola Queirolo, Adnan Khattak, Anders Jespersen, Daniela Kleine-Kohlbrecher, Nadia Viborg, Mads Lausen, Stine F Thorsen, Thomas Trolle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/71b5b7000a494548b6f07ae48b302987
Autor:
Sofie Kirial Mørk, Mohammad Kadivar, Kalijn Fredrike Bol, Arianna Draghi, Marie Christine Wulff Westergaard, Signe Koggersbøl Skadborg, Nana Overgaard, Anders Bundgård Sørensen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Christina Westmose Yde, Thomas Trolle, Christian Garde, Jens Friis-Nielsen, Nis Nørgaard, Dennis Christensen, Jens Vindahl Kringelum, Marco Donia, Sine Reker Hadrup, Inge Marie Svane
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The majority of neoantigens arise from unique mutations that are not shared between individual patients, making neoantigen-directed immunotherapy a fully personalized treatment approach. Novel technical advances in next-generation sequencing of tumor
Externí odkaz:
https://doaj.org/article/7abb393630304338a7037f295b6ab061
Autor:
Nikolas Hallberg Thuesen, Michael Schantz Klausen, Shyam Gopalakrishnan, Thomas Trolle, Gabriel Renaud
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Identifying the specific human leukocyte antigen (HLA) allele combination of an individual is crucial in organ donation, risk assessment of autoimmune and infectious diseases and cancer immunotherapy. However, due to the high genetic polymorphism in
Externí odkaz:
https://doaj.org/article/99051a4a65b941b4b8ec147220b753d9
Autor:
Emma C. Jappe, Christian Garde, Sri H. Ramarathinam, Ethan Passantino, Patricia T. Illing, Nicole A. Mifsud, Thomas Trolle, Jens V. Kringelum, Nathan P. Croft, Anthony W. Purcell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Thermostability of the peptide-MHC interaction is important for immunogenicity. Here the authors present a mass spectrometry method to measure thermostability among thousands of peptide-MHC complexes in parallel and a trained artificial neural networ
Externí odkaz:
https://doaj.org/article/5cf6ee2c88c54b69ae8a7c1723f4491d
Autor:
Curtis McMurtrey, Thomas Trolle, Tiffany Sansom, Soumya G Remesh, Thomas Kaever, Wilfried Bardet, Kenneth Jackson, Rima McLeod, Alessandro Sette, Morten Nielsen, Dirk M Zajonc, Ira J Blader, Bjoern Peters, William Hildebrand
Publikováno v:
eLife, Vol 5 (2016)
HLA class I presentation of pathogen-derived peptide ligands is essential for CD8+ T-cell recognition of Toxoplasma gondii infected cells. Currently, little data exist pertaining to peptides that are presented after T. gondii infection. Herein we pur
Externí odkaz:
https://doaj.org/article/d6ec5e3dbf06448d828994a65c08570a
Autor:
Georgina V Long, Pier Francesco Ferrucci, Adnan Khattak, Tarek M Meniawy, Patrick Alexander Ott, Michael Chisamore, Thomas Trolle, Agon Hyseni, Erik Heegaard
Publikováno v:
Future Oncology. 18:3473-3480
Despite improvements made with checkpoint inhibitor (CPI) therapy, a need for new approaches to improve outcomes for patients with unresectable or metastatic melanoma remains. EVX-01, a personalized neoepitope vaccine, combined with pembrolizumab tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37393f2e34de40451f8380c1da2af13b
https://doi.org/10.2217/fon-2022-0694
https://doi.org/10.2217/fon-2022-0694
Autor:
Christian Garde, Michail A. Pavlidis, Pablo Garces, Emma J. Lange, Sri H. Ramarathinam, Mateo Sokač, Kirti Pandey, Pouya Faridi, Johanne Ahrenfeldt, Shanzou Chung, Stine Friis, Daniela Kleine-Kohlbrecher, Nicolai J. Birkbak, Jens V. Kringelum, Birgitte Rønø, Anthony W. Purcell, Thomas Trolle
SUMMARYCancer immunotherapies have greatly improved the treatment of several cancers, albeit a large fraction of patients still does not benefit from such treatments. Personalized therapies are envisioned to lead to improved outcomes, yet they have l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6d907ea0484dab60693968a532d99f
https://doi.org/10.1101/2023.03.23.533908
https://doi.org/10.1101/2023.03.23.533908
Autor:
Nikolas Hallberg Thuesen, Michael Shantz Klausen, Shyam Gopalakrishnan, Thomas Trolle, Gabriel Renaud
The human leukocyte antigen (HLA) system is a group of genes coding for proteins that are central to the adaptive immune system and identifying the specific HLA allele combination of a patient is relevant in organ donation, risk assessment of autoimm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0790fed0f43ea6736e4c089c15ef40
https://doi.org/10.1101/2022.06.28.497888
https://doi.org/10.1101/2022.06.28.497888