Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thomas Tiller"'
Autor:
Thomas, Tiller
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::638d533f87cb509bb82724a0589564c6
https://pubmed.ncbi.nlm.nih.gov/28255887
https://pubmed.ncbi.nlm.nih.gov/28255887
Autor:
Thomas Tiller
Publikováno v:
Methods in Molecular Biology ISBN: 9781493968558
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c2153813760602078ec23272bdc7c1
https://doi.org/10.1007/978-1-4939-6857-2_27
https://doi.org/10.1007/978-1-4939-6857-2_27
Autor:
Yvonne Stark, Stefan Kaden, Dominique Poujol, Daniela Daubert, Karin Felderer, Jennifer Stehle, Katja Siegers, Stefanie Urlinger, Tanja Herrmann, Ingrid Schuster, Ralf Strohner, Johanna Kölln, Martin Heßling, Markus Enzelberger, Thomas Tiller, Dorothée Deppe, Marion Berenguer
Publikováno v:
mAbs
This report describes the design, generation and testing of Ylanthia, a fully synthetic human Fab antibody library with 1.3E+11 clones. Ylanthia comprises 36 fixed immunoglobulin (Ig) variable heavy (VH)/variable light (VL) chain pairs, which cover a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13e70c347531d280c6341065e3428a0
https://doi.org/10.4161/mabs.24218
https://doi.org/10.4161/mabs.24218
Autor:
Thomas Tiller
Publikováno v:
New Biotechnology
Monoclonal antibodies (mAbs) are arguably the most significant class of biologics for use as pharmaceuticals and diagnostics. Many technological concepts exist for the generation and identification of therapeutically relevant mAbs, including the isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bc04776cf44c2919571ade0bd53750
https://doi.org/10.1016/j.nbt.2011.03.014
https://doi.org/10.1016/j.nbt.2011.03.014
Publikováno v:
Journal of Immunological Methods. 350:183-193
We have established a highly efficient 96-well format based strategy to characterize the expressed murine antibody repertoire by combining immunoglobulin (Ig) gene cloning with antibody expression and reactivity profiling at the single cell level. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ec9dd996cf86cbd04e71cb5bb29ef5
https://doi.org/10.1016/j.jim.2009.08.009
https://doi.org/10.1016/j.jim.2009.08.009
Autor:
Eric Meffre, Makoto Tsuiji, Sergey Yurasov, Michel C. Nussenzweig, Thomas Tiller, Hedda Wardemann
Publikováno v:
Journal of Immunological Methods
We have developed an efficient strategy that combines immunoglobulin (Ig) gene repertoire analysis and Ig reactivity profiling at the single cell level. Based on surface marker expression individual cells at different stages of human B cell developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0872fedfe8b7cd4cf1b843c8599a90f
Autor:
Makoto Tsuiji, Klara Velinzon, Michel C. Nussenzweig, Hedda Wardemann, Sergey Yurasov, Thomas Tiller, Virginia Pascual
Publikováno v:
The Journal of Experimental Medicine
A majority of the antibodies expressed by nascent B cells in healthy humans are self-reactive, but most of these antibodies are removed from the repertoire during B cell development. In contrast, untreated systemic lupus erythematosus (SLE) patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10a484e766eb612f70f785252aec1c8
http://europepmc.org/articles/PMC2118096
http://europepmc.org/articles/PMC2118096
Autor:
Stefan Kaden, Stefan Pabst, Jan Jaehrling, Mechthild Linnemann, Karin Felderer, Anne Höhne, Sebastian Jäger, Bodo Brocks, Daniela Daubert, Tobias Neuber, Thomas Tiller, Johanna Kölln, Ralf Ostendorp, Katrin Frese
Publikováno v:
mAbs. 6(4)
The neonatal Fc receptor (FcRn) protects immunoglobulin G (IgG) from degradation and increases the serum half-life of IgG, thereby contributing to a higher concentration of IgG in the serum. Because altered FcRn binding may result in a reduced or pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574f56e9a6c30aeb8f46e22092358ce0
https://pubmed.ncbi.nlm.nih.gov/24802048
https://pubmed.ncbi.nlm.nih.gov/24802048
Publikováno v:
Synlett. 1993:535-538
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c68eb4ce539e44f5ed722ed8c7e6fc0
https://doi.org/10.1055/s-1993-22520
https://doi.org/10.1055/s-1993-22520
Autor:
Felix Oden, Marc Ehlers, Cornelia Kreschel, Christian E. Busse, Hedda Wardemann, Thomas Tiller, Juliane Kofer, Stefan Riebel, Maria M.M. Mertes, Susanne Wickert
Publikováno v:
The Journal of Experimental Medicine
The leukemogenic effects of Myc drive recurrent trisomy in a mouse model of acute myeloid leukemia.
Abnormalities in expression levels of the IgG inhibitory Fc gamma receptor IIB (FcγRIIB) are associated with the development of immunoglobulin (
Abnormalities in expression levels of the IgG inhibitory Fc gamma receptor IIB (FcγRIIB) are associated with the development of immunoglobulin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d62c14c67889dc1c7b4904a691db8a
https://pubmed.ncbi.nlm.nih.gov/21078890
https://pubmed.ncbi.nlm.nih.gov/21078890