Small-Molecule Positive Allosteric Modulators of the β2-Adrenoceptor Isolated from DNA-Encoded Libraries

Autor: Laura M. Wingler, Biswaranjan Pani, Dean P. Staus, Paula K. Rambarat, Paul J. Shim, Robert J. Lefkowitz, Jin Lei, Thomas Franch, Mikkel Vestergaard, Lillian D. Sun, Eva Kampmann Olsen, Thomas T. Xu, Li-Yin Huang, Shuai Zhao, Seungkirl Ahn, Gitte Nystrup Husemoen, Alem W. Kahsai, Rishabh K. Simhal, Xin Chen

Publikováno v: Molecular Pharmacology

Conventional drug discovery efforts at the β2-adrenoceptor (β2AR) have led to the development of ligands that bind almost exclusively to the receptor’s hormone-binding orthosteric site. However, targeting the largely unexplored and evolutionarily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8cb23648cdfae42cf2c744bde85237
http://europepmc.org/articles/PMC6022804

Treatment of Persistent Soiling in Hirschsprung Disease With Antegrade Continence Enemas.

Autor: Xu T; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia. Electronic address: toxu@childrensnational.org., Hanke R; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Samuk I; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Russell TL; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Rana MS; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Tiusaba L; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Jacobs SE; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Bokova E; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Varda BK; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Teeple E; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Badillo AT; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Levitt MA; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia., Feng C; Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia.

Publikováno v: The Journal of surgical research [J Surg Res] 2024 Oct; Vol. 302, pp. 411-419. Date of Electronic Publication: 2024 Aug 16.

Evaluating the July Effect in Oral and Maxillofacial Surgery: Part I-Mandibular Fractures.

Autor: Jazayeri HE; DMD Candidate, University of Pennsylvania, Philadelphia, PA., Xu T; Resident, Department of Surgery, Rush University Medical Center, Chicago, IL., Khavanin N; Resident, Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD., Dorafshar AH; Professor and Chief, Division of Plastic and Reconstructive Surgery, Rush University Medical Center, Chicago, IL., Peacock ZS; Assistant Professor, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA. Electronic address: zpeacock@partners.org.

Publikováno v: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [J Oral Maxillofac Surg] 2020 Feb; Vol. 78 (2), pp. 248-253. Date of Electronic Publication: 2019 Aug 09.

Management of Teeth in the Line of Mandibular Angle Fractures Treated with Open Reduction and Internal Fixation: A Systematic Review and Meta-Analysis.

Autor: Khavanin N; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Jazayeri H; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Xu T; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Pedreira R; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Lopez J; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Reddy S; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Shamliyan T; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Peacock ZS; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine., Dorafshar AH; From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital; the Department of Oral and Maxillofacial Surgery, University of Pennsylvania Health System; the Division of Plastic Surgery, Rush University Medical Center; Quality Assurance, Evidence-Based Medicine Center, Elsevier; and the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine.

Publikováno v: Plastic and reconstructive surgery [Plast Reconstr Surg] 2019 Dec; Vol. 144 (6), pp. 1393-1402.

Metabolic and endocrine consequences of social stress in a visible burrow system.

Autor: Tamashiro KL; Department of Psychiatry, University of Cincinnati Medical Center, 231 Albert Sabin Way, Box 670559, Cincinnati, OH 45267-0559, USA., Nguyen MM, Fujikawa T, Xu T, Yun Ma L, Woods SC, Sakai RR

Publikováno v: Physiology & behavior [Physiol Behav] 2004 Feb; Vol. 80 (5), pp. 683-93.