Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Thomas T Murooka"'
Autor:
Alain Pulfer, Diego Ulisse Pizzagalli, Paolo Armando Gagliardi, Lucien Hinderling, Paul Lopez, Romaniya Zayats, Pau Carrillo-Barberà, Paola Antonello, Miguel Palomino-Segura, Benjamin Grädel, Mariaclaudia Nicolai, Alessandro Giusti, Marcus Thelen, Luca Maria Gambardella, Thomas T Murooka, Olivier Pertz, Rolf Krause, Santiago Fernandez Gonzalez
Publikováno v:
eLife, Vol 12 (2024)
Intravital microscopy has revolutionized live-cell imaging by allowing the study of spatial–temporal cell dynamics in living animals. However, the complexity of the data generated by this technology has limited the development of effective computat
Externí odkaz:
https://doaj.org/article/7e7d13c61fdf4ad4b1ddfbc78e28f7a6
Autor:
Nicolas Bellini, Robert Lodge, Tram N.Q. Pham, Jaspreet Jain, Thomas T. Murooka, Alon Herschhorn, Nicole F. Bernard, Jean-Pierre Routy, Cécile L. Tremblay, Éric A. Cohen
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105234- (2022)
Summary: Activated-to-memory transitioning CD4+ T cells display elevated expression of the HIV-1 co-receptor CCR5 and are more prone to HIV-1 latent infection. Here, we show that p53-regulated miRNA-103 downmodulates CCR5 levels in CD4+ T lymphocytes
Externí odkaz:
https://doaj.org/article/30d4e7980f46475a9a5b3a72a2a0365d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The risk of HIV acquisition is low on a per-contact basis but increased by transmission co-factors such as other sexually transmitted infections (STIs). Human papillomavirus (HPV) is a prevalent STI that most individuals will acquire HPV in their lif
Externí odkaz:
https://doaj.org/article/98b7b0be373440d9931bc2515c832d58
Autor:
Tadashi Hosoya, Dunai Cordelia, Benedict D. Michael, Chie Miyabe, Jun Nagai, Thomas T. Murooka, Yoshishige Miyabe
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b2dc61fcf98c44f4aca7dfa7816648a0
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intravital microscopy, such as 2-photon microscopy, is now a mainstay in immunological research to visually characterize immune cell dynamics during homeostasis and pathogen infections. This approach has been especially beneficial in describing the c
Externí odkaz:
https://doaj.org/article/65df8d197ed9480fae470a39bf9b8754
Autor:
Gaurav Gupta, Zhirong Mou, Ping Jia, Rohit Sharma, Romaniya Zayats, Sayonara M. Viana, Lianyu Shan, Aldina Barral, Viviane S. Boaventura, Thomas T. Murooka, Abdel Soussi-Gounni, Camila I. de Oliveira, Jude E. Uzonna
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108513- (2020)
Summary: The long pentraxin 3 (PTX3) plays a critical role in inflammation, tissue repair, and wound healing. Here, we show that PTX3 regulates disease pathogenesis in cutaneous leishmaniasis (CL). PTX3 expression increases in skin lesions in patient
Externí odkaz:
https://doaj.org/article/aaefd71d64124fd1a867b9f493e7fb4a
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100203- (2020)
Summary: Immune cells migrate and communicate through cell-to-cell interactions and cytokines to coordinate the specificity and timing of the immune response. While studying these events in cell culture are standard procedure, spatiotemporal dynamics
Externí odkaz:
https://doaj.org/article/0df31cb2a2a44fd7951e9409034edb37
Autor:
Wan Hon Koh, Paul Lopez, Oluwaseun Ajibola, Roshan Parvarchian, Umar Mohammad, Ryan Hnatiuk, Jason Kindrachuk, Thomas T. Murooka
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101427- (2020)
Summary: Trafficking of cell-associated HIV-1 from the genital mucosa to lymphoid organs represents a critical first step toward systemic infection. Mature DCs capture and transmit HIV-1 to T cells, but insights into DC-to-T cell viral spread dynamic
Externí odkaz:
https://doaj.org/article/10b58e347e704367b72fde1bee4c5c60
Autor:
Sarah Brendle, Jingwei J. Li, Nancy M. Cladel, Debra A. Shearer, Lynn R. Budgeon, Karla K. Balogh, Hannah Atkins, Marina Costa-Fujishima, Paul Lopez, Neil D. Christensen, John Doorbar, Thomas T. Murooka, Jiafen Hu
Publikováno v:
Viruses, Vol 13, Iss 9, p 1824 (2021)
Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth with a newly establishe
Externí odkaz:
https://doaj.org/article/1a3b57b1851d435f82214a82c7040daf
Autor:
Marina Costa-Fujishima, Atta Yazdanpanah, Samantha Horne, Alana Lamont, Paul Lopez, Christina Farr Zuend, Kenzie Birse, Morgan Taverner, Riley Greenslade, Max Abou, Laura Noel-Romas, Bernard Abrenica, Oluwaseun Ajibola, Nnamdi Ikeogu, Ruey-Chyi Su, Lyle R. McKinnon, Helen Pymar, Vanessa Poliquin, Alicia R. Berard, Adam D. Burgener, Thomas T. Murooka
Publikováno v:
Mucosal Immunology.