Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thomas T Kawabe"'
Autor:
Tamás eKiss, William E Hoffmann, Liam eScott, Thomas T Kawabe, Anthony J Milici, Erik A Nilsen, Mihály eHajós
Publikováno v:
Frontiers in Psychiatry, Vol 2 (2011)
NMDA receptor (NMDAR) antagonists, such as phencyclidine, ketamine or dizocilpine (MK-801) are commonly used in psychiatric drug discovery in order to model several symptoms of schizophrenia, including psychosis and impairments in working memory. In
Externí odkaz:
https://doaj.org/article/ba0c78de55b1414ca3a4098c074855cd
Autor:
Magalie Boucher, Karen Walters, Casey Ritenour, Hayley N Pryski, Alan C. Opsahl, Christopher Somps, Peter R. Mouton, Chang-Ning Liu, Thomas T. Kawabe, Germaine Boucher
Publikováno v:
Toxicologic Pathology. 48:228-237
The potential for neurogenesis in the cranial (superior) cervical ganglia (SCG) of the sympathetic nervous system was evaluated. Eleven consecutive daily doses of guanethidine (100 mg/kg/d) were administered intraperitoneally to rats in order to dest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f81d4215105a0c288293a445dfc3ac4
https://doi.org/10.1177/0192623319843052
https://doi.org/10.1177/0192623319843052
Autor:
Samuel Bell, Tristan S. Maurer, Athanasia Skoura, Dexue Sun, Thomas T. Kawabe, Wei Zheng, Jessica Ward, Chunyan Su, Kent J. Johnson, Amit Kalgutkar, Carlin Okerberg, Bhupesh Kapoor, Kay Ahn, Leonard Buckbinder, Christian Cortes, Roscoe L. Warner, Paul Bonin, Yanwei Zhang, Walter Bobrowski, Timothy M. Coskran, Roger B. Ruggeri
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 353:288-298
Small vessel vasculitis is a life-threatening condition and patients typically present with renal and pulmonary injury. Disease pathogenesis is associated with neutrophil accumulation, activation, and oxidative damage, the latter being driven in larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd3bca61309a5409f5b2842b97e56f6
https://doi.org/10.1124/jpet.114.221788
https://doi.org/10.1124/jpet.114.221788
Autor:
Thomas T. Kawabe, Yasmina Noubia Abdiche, Jaume Pons, Danielle Pappas, Kelly R. Bales, Sherry L. La Porte, Ons Harrabi, Wei-Hsien Ho, Thomas A. Lanz, John C. Lin, Dione Kobayashi, Anthony J. Milici, Erene W. Mina, Sangeetha Bollini, Alexander S. Rusnak
Publikováno v:
Journal of Molecular Biology. 421:525-536
Alzheimer's disease, the most common cause of dementia in the elderly and characterized by the deposition and accumulation of plaques, is composed in part of β-amyloid (Aβ) peptides, loss of neurons, and the accumulation of neurofibrillary tangles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717072f61f2124ef01333507670f1904
https://doi.org/10.1016/j.jmb.2011.11.047
https://doi.org/10.1016/j.jmb.2011.11.047
Publikováno v:
Neurobiology of aging. 37
Development of neurofibrillary tangles in Alzheimer's disease correlates with neuronal loss and dementia. Transgenic Tg4510 mice model the tauopathy of the disease, with these mice exhibiting progressive, region-specific neuronal loss, and behavioral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbed8041677b762d1c8785c10be99ca
https://pubmed.ncbi.nlm.nih.gov/26610388
https://pubmed.ncbi.nlm.nih.gov/26610388
Autor:
Gabriel Vogeli, Daniel J. Waldon, Vince Groppi, Thomas T. Kawabe, Linda S. Wood, Paul S. Kaytes, Thomas E. Wagner, Thomas J. Rea, Allen E. Buhl, Alistair R. McNab
Publikováno v:
Annals of the New York Academy of Sciences. 642:21-30
We analyzed the effect of minoxidil on hair follicles isolated from transgenic mice. These transgenic animals synthesize the reporter enzyme CAT in their hair follicles only during the active phases of hair growth. The recombinant gene used to genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a928295dc7931cc7e4f222f6fa2000a5
https://doi.org/10.1111/j.1749-6632.1991.tb24377.x
https://doi.org/10.1111/j.1749-6632.1991.tb24377.x
Autor:
Thomas T. Kawabe, Karl Kappenman, Roger A. Poorman, Barry S. Lutzke, Dennis E. Epps, Antonio Molinari, Ronald W. Sarver, Allen E. Buhl, Bruce M. Taylor, Gregory J. Fici
Publikováno v:
Journal of Protein Chemistry. 22:31-40
The time dependency of the spontaneous aggregation of the fibrillogenic beta-amyloid peptide, Abeta1-40, was measured by turbidity, circular dichroism, HPLC, and fluorescence polarization. The results by all methods were comparable and they were most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbd06409a74d4cc1d4f1a2d9b233cac
https://doi.org/10.1023/a:1023063626770
https://doi.org/10.1023/a:1023063626770
Autor:
Adam W. Hudson, John M. Kreeger, Christopher J. Bowman, Mitchell Thorn, Mark Collinge, Thomas T. Kawabe
Publikováno v:
Journal of immunotoxicology. 12(4)
Delayed-type hypersensitivity (DTH) is a T-cell-mediated immune response that may be used for immunotoxicity testing in non-clinical species. However, in some cases DTH assays using T-dependent antigens may be confounded by the production of antibodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7e90d9bb6a708d4975f4eaa5eab8e0
https://pubmed.ncbi.nlm.nih.gov/25412622
https://pubmed.ncbi.nlm.nih.gov/25412622
Autor:
Ismail Kola, Weiqun Liu, Kjell A. Svensson, Mary E. Shuck, Hartmut Tintrup, Sarah Wright, John A. Wijsman, Karen S. Chen, Lisa McConlogue, Thomas T. Kawabe, John P. Anderson, Kang Hu, Guriqbal Basi, Michael Power, Steven L. Roberds, Karl Kappenman, Dale Schenk, Stephen B. Freedman, Michael Schoor, Normand Frigon, David W. Robertson, Ralf Kuehn, Dora Kate Games, Sukanto Sinha, George Shopp, Kelly Johnson-Wood, Nanette F. Nichols, Michael Jerome Bienkowski, Mike Lee, Gwen Tatsuno, Ruth Motter, Daniel G. Branstetter
Publikováno v:
Human Molecular Genetics. 10:1317-1324
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by accumulation of amyloid plaques and neurofibrillary tangles in the brain. The major components of plaque, beta-amyloid peptides (Abetas), are produced from amyloid precursor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62941ba2369e7d9bf17cea82323484d
https://doi.org/10.1093/hmg/10.12.1317
https://doi.org/10.1093/hmg/10.12.1317
Autor:
David Riddell, Chester J. Siok, Eva Hajos-Korcsok, Tamás Kiss, Brian D. Harvey, Anthony J. Milici, Warren D. Hirst, Thomas T. Kawabe, Liam Scott, Mihály Hajós, Jianlin Feng, Elie Needle, Kevin Atchison
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7116e95ef9cd4bc3d790ff2ef91a6a6
https://doi.org/10.1016/j.jalz.2011.05.1661
https://doi.org/10.1016/j.jalz.2011.05.1661