Výsledky vyhledávání - "Thomas Staigers"

Technology Considerations to Enable the Risk-Based Monitoring Methodology

Autor: Shelly Barnes, Thomas Staigers, Nareen Katta, Neil Sanford, Thomas Verish

Publikováno v: Therapeutic innovationregulatory science. 48(5)

TransCelerate BioPharma Inc developed a methodology based on the notion that shifting monitoring processes from an excessive concentration on source data verification to comprehensive risk-driven monitoring will increase efficiencies and enhance pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bfa0860ff31ada2f913172b86f26c4
https://pubmed.ncbi.nlm.nih.gov/30231440

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A practical synthesis of 3(S)-methyl-heptanoic acid from (S)-citronellol

Autor: Thomas Staigers, Susan L. Pezzullo, Chiu Charles K, Ralph Breitenbach, Stephen S. Massett, Morgan Meltz, C.William Murtiashaw

Publikováno v: Tetrahedron: Asymmetry. 7:435-442

Chiral 3-methyl-heptanoic acid is readily accessible by functional group manipulation of optically active citronellol. In principle, this approach is general and could be applied to the synthesis of chiral 3-methyl-alkanoic acids seven carbon atoms i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35133caf66f8787bb54dfb99fe7f146c
https://doi.org/10.1016/0957-4166(96)00026-2

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Determination of the activation parameters and the mechanism for atropisomerization of (S )-3-(2-chlorophenyl)-2-[2-(6-diethylaminomethylpyridin-2-yl)vinyl]-6-fluoroquinazolin-4(3H )-one †

Autor: Thomas Staigers, Devries Keith Michael, Jari I. Finneman, Vasu C. Sekhar, Lisa Newell

Publikováno v: Journal of the Chemical Society, Perkin Transactions 2. :961-963

Values of ΔH‡ = 111.6 ± 0.3 kJ mol−1 (26.7 ± 0.1 kcal mol−1) and ΔS‡ = −25.7 ± 0.9 J K−1 mol−1 (−6.1 ± 0.2 cal K−1 mol−1) have been determined for the atropisomerization of (S)-3-(2-chlorophenyl)-2-[2-(6-diethylaminomethylpy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::406fa5c2de03e68a6dad4454e968d47f
https://doi.org/10.1039/b010090k

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ChemInform Abstract: A Practical Synthesis of 3(S)-Methyl-heptanoic Acid from (S)- Citronellol

Autor: Chiu Charles K, Thomas Staigers, Steve S. Massett, Susan L. Pezzullo, Morgan Meltz, Murtiashaw Charles W, Ralph Breitenbach

Publikováno v: ChemInform. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0fccc769edefb2acb9f3ff14752292f
https://doi.org/10.1002/chin.199625188

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Periodical

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