Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Thomas Snoeks"'
Autor:
Marieke A. Stammes, Azusa Maeda, Jiachuan Bu, Deborah Scollard, Iris Kulbatski, Philip J. Medeiros, Riccardo Sinisi, Elena A. Dubikovskaya, Thomas Snoeks, Ermond R. van Beek, Alan Chan, Clemens W. G. M. Löwik, Ralph S. DaCosta
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
Purpose: Most effective antitumor therapies induce tumor cell death. Non-invasive, rapid and accurate quantitative imaging of cell death is essential for monitoring early response to antitumor therapies. To facilitate this, we previously developed a
Externí odkaz:
https://doaj.org/article/91d7a66d476f4edfb9345fb306e79769
Publikováno v:
Nature Protocols.
Autor:
Jacqueline J.T. Marshall, Joshua J. Cull, Hajed O. Alharbi, May Zaw Thin, Susanna T.E. Cooper, Christopher Barrington, Hannah Vanyai, Thomas Snoeks, Bernard Siow, Alejandro Suáarez-Bonnet, Eleanor Herbert, Daniel J. Stuckey, Angus J.M. Cameron, Fabrice Prin, Andrew C. Cook, Simon L. Priestnall, Sonia Chotani, Owen J. L. Rackham, Daniel N. Meijles, Tim Mohun, Angela Clerk, Peter J. Parker
BackgroundThe protein kinase PKN2 is required for embryonic development, and PKN2 knockout mice die as a result of failure in expansion of mesoderm tissues, cardiac development and neural tube closure. In the adult, cardiomyocyte PKN2 and PKN1 (in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da3f19d1a8b0542a8afece9e9c2fa48
https://openaccess.sgul.ac.uk/id/eprint/114588/1/bcj-2022-0281.pdf
https://openaccess.sgul.ac.uk/id/eprint/114588/1/bcj-2022-0281.pdf
Publikováno v:
Nature protocols.
X-ray computed tomography is a reliable technique for the detection and longitudinal monitoring of pulmonary nodules. In preclinical stages of diagnostic or therapeutic development, the miniaturized versions of the clinical computed tomography scanne
Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
Autor:
Ander Abarrategi, Henry Wood, Alexander E. Smith, Kar Lok Kong, Syed A Mian, Linda Ariza-McNaughton, Thomas Snoeks, Peter Johnson, Caroline A. Oedekoven, Ghulam J. Mufti, Kevin Rouault-Pierre, Antoniana Batsivari, Dominique Bonnet
Publikováno v:
Blood Cancer Discov
Myelodysplastic syndromes (MDS) are clonal stem cell diseases characterized mainly by ineffective hematopoiesis. Here, we present an approach that enables robust long-term engraftment of primary MDS stem cells (MDS-SC) in mice by implantation of huma
Autor:
Yolanda Saavedra-Torres, Thomas Snoeks, Dinis Pedro Calado, Bernard D Maybury, Jude Fitzgibbon
Publikováno v:
Methods in Molecular Biology ISBN: 9781071616680
Enforced activation of NF-κB signaling can be achieved by constitutive NF-κB-inducing kinases, IKK2 and NIK, or via lymphoma-associated mutants of MYD88, CARD11, and CD79B. In order to model Diffuse Large B Cell Lymphoma (DLBCL) in mice, conditiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60e2b570fa9939d1f9b7a93538507a2
https://doi.org/10.1007/978-1-0716-1669-7_20
https://doi.org/10.1007/978-1-0716-1669-7_20
Autor:
Rebecca E. Saunders, Oriane Guillermin, Timothy J. Mohun, Alexander Howson, Fabrice Prin, Thomas Snoeks, Barry J. Thompson, Michael Howell, Bishara Marzook, Hannah Vanyai, Stefan Boeing
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The Hippo-YAP/TAZ pathway is an important regulator of tissue growth, but can also control cell fate or tissue morphogenesis. Here, we investigate the function of the Hippo pathway during the development of cartilage, which forms the majority of the
Autor:
Dominique Bonnet, Thomas Snoeks, Ander Abarrategi, Giuseppe Gasparre, Nikkitha Umesh Ganesh, Ivana Kurelac, Anna Maria Porcelli, Luisa Iommarini, Moira Ragazzi, Ilaria Malanchi
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine; Volume 8; Issue 12; Pages: 2184
Journal of Clinical Medicine; Volume 8; Issue 12; Pages: 2184
A cogent issue in cancer research is how to account for the effects of tumor microenvironment (TME) on the response to therapy, warranting the need to adopt adequate in vitro and in vivo models. This is particularly relevant in the development of str