Data from Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors

Autor: Primo N. Lara, Chong-Xian Pan, David R. Gandara, Thomas Semrad, I-Yeh Gong, Karen Kelly, Mrinal P. Dutia, Tianhong Li, Nichole Mahaffey, Taiwo Akande, Monica Diaz, John S. Bomalaski, James A. Thomson, Benjamin K. Tomlinson

Purpose: This phase I study examined the toxicity and tolerability of pegylated arginine deiminase (ADI-PEG 20) in combination with docetaxel in patients with advanced solid malignancies.Experimental Design: Eligible patients had histologically prove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b989945facad1d88a7e19a5c6644bfb
https://doi.org/10.1158/1078-0432.c.6523874.v1

Significant Clinical Response to a MEK Inhibitor Therapy in a Patient With Metastatic Melanoma Harboring an

Autor: Kevin B, Kim, Thomas, Semrad, Alexa B, Schrock, Siraj M, Ali, Jeffrey S, Ross, Mark, Singer, Mohammed, Kashani-Sabet

Publikováno v: JCO precision oncology. 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6910a9063815e13a38e9dec12a02dbde
https://pubmed.ncbi.nlm.nih.gov/35135096

Mutational analysis of immunoglobulin germline derived Vλ4A light chains in rheumatoid arthritis

Autor: Thomas Semrad, Kenny, T. P., Malyj, W., Robbins, D. L.

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e0b56b90d98990b165a8681c39ac009
http://www.scopus.com/inward/record.url?eid=2-s2.0-16344380240&partnerID=MN8TOARS

Significant Clinical Response to a MEK Inhibitor Therapy in a Patient With Metastatic Melanoma Harboring an RAF1 Fusion.

Autor: Kim KB; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY., Semrad T; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY., Schrock AB; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY., Ali SM; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY., Ross JS; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY., Singer M; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY., Kashani-Sabet M; Kevin B. Kim, Mark Singer, and Mohammed Kashani-Sabet, California Pacific Medical Center Research Institute, San Francisco; Thomas Semrad, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, CA; Alexa B. Schrock, Siraj M. Ali, and Jeffrey S. Ross, Foundation Medicine, Cambridge, MA; and Jeffrey S. Ross, Albany Medical College, Albany, NY.

Publikováno v: JCO precision oncology [JCO Precis Oncol] 2018 Nov; Vol. 2, pp. 1-6.