Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas Seib"'
Autor:
Gerhardt Seitz, Birgit Theisinger, Karin Hilgert, Markus Seifert, Cornelius Welter, Manfred Stolte, Matthias Engel, Thomas Seib
Publikováno v:
Human Genetics. 100:515-519
The nm23-H1 gene has been suggested to be a metastasis suppressor gene. Studies about the events of loss of heterozygosity (LOH) at the nm23 locus and its correlation to metastasis are controversially discussed. To optimize detection of LOH at the nm
Publikováno v:
Leukemia Research. 20:429-439
Specific binding of nuclear proteins to the region of transcriptional attenuation has been shown to modulate the expression of c-myb, a nuclear proto-oncogene preferentially expressed in lympho-hematopoietic cells. Here, it plays an important role in
Autor:
Matthias Engel, Michel Véron, Birgit Theisinger, Thomas Seib, Marie-Lise Lacombe, Steven Dooley, Cornelius Welter
Publikováno v:
European Journal of Biochemistry. 234:200-207
Two human nm23 genes have been identified, designated nm23-H1 and nm23-H2, which encode the 88% identical nucleoside-diphosphate kinase (NDPK) A and NDPK B polypeptides, respectively. The nm23-H1 gene product has been shown to play a functional role
Characterization of the Human NM23-H2 Promoter Region and Localization of the Microsatellite D17S396
Publikováno v:
Biochemical and Biophysical Research Communications. 215:910-914
The transcription of human nm23 genes (nm23-H1, nm23-H2) is involved in suppression of tumor metastasis or tumor progression. Therefore the characterization of transcriptional regulatory mechanisms for both nm23 genes is very important. In this study
Publikováno v:
Biochemical and Biophysical Research Communications. 214:195-199
Trefoil proteins form a specific group of stable secretory polypeptides. They are expressed in a lot of human cancers and inflammatory processes of the gastrointestinal tract. Recently a new human trefoil protein, ITF/hP1.B was isolated. This gene is
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1219:285-292
The molecular mechanisms that modulate c-myb mRNA transcription in hematopoietic cells appear to involve intron regulatory sequences. We have characterized the fourth of ten introns from both human and murine c-myb genes in regard to nucleotide seque
Autor:
Birgit Theisinger, Cornelius Welter, Markus Seifert, Nikolaus Blin, Klaus-Dieter Zang, Thomas Seib, Karin Hilgert, Steven Dooley, Matthias Engel
Publikováno v:
Genomics. 40:200-202
Publikováno v:
Human Genetics. 97
Hereditary nonpolyposis colorectal cancer (HN-PCC) is one of man's commonest hereditary diseases. Several studies have identified four responsible genes that are involved in a process known as DNA mismatch repair; hMSH2 is the most important of these
Autor:
Klaus Piontek, Klaus-Dieter Zang, Heike Janz, Steven Dooley, Matthias Engel, Cornelius Welter, Birgit Theisinger, Thomas Seib
Publikováno v:
Human genetics. 93(1)
Nm23-H1 gene expression is inversely correlated with tumor metastatic potential in certain tumors, including melanomas, breast carcinomas, and hepatocellular carcinomas. Using nm23-H1 c-DNA primer and genomic polymerase chain reaction (PCR) amplifica
Autor:
Christoph Süss-Havemann, Janina Kosan, Thomas Seibold, Nils Martin Dibbern, Anne Daubmann, Jens Christian Kubitz, Stefanie Beck
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background The Kids save lives statement recommends annual Basic Life Support (BLS) training for school children but the implementation is challenging. Trainings should be easy to realise and every BLS training should be as effective as poss
Externí odkaz:
https://doaj.org/article/80e379f40c2e40edb408dfa5160cf6c6