Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas Seebacher"'
Publikováno v:
The EMBO Journal. 20:3667-3675
The gene Rv1625c from Mycobacterium tuberculosis encodes a membrane-anchored adenylyl cyclase corresponding to exactly one-half of a mammalian adenylyl cyclase. An engineered, soluble form of Rv1625c was expressed in Escherichia coli. It formed a hom
Publikováno v:
European Journal of Biochemistry. 268:105-110
The nine membrane-bound mammalian adenylyl cyclases (ACs) contain two highly diverged membrane anchors, M1 and M2, with six transmembrane spans each and two conserved cytosolic domains which coalesce into a pseudoheterodimeric catalytic unit. Previou
Autor:
Peter H. Vogt, Angela Edelmann, Anna Jauch, Jane Morell, Thomas Seebacher, Zhihong Shan, Peter Urbitsch, P. Hirschmann
Publikováno v:
Human Molecular Genetics. 5:2005-2011
We have isolated a series of human testis poly(A) cDNA clones by cross-hybridization to SPGY1, a Y gene homologous to DAZ. Their sequence analysis revealed an identical nucleotide composition in different 'full-length' clones, suggesting that all wer
Publikováno v:
Experimental Cell Research. 203:504-507
Induction of rat liver epithelial cell migration by epidermal growth factor (EGF) changes the expression pattern of secreted proteins. The expression of the early induced glycoprotein EGF-inducible protein No. 1 (EIP-1) correlates with the migratory
Publikováno v:
Experimental Cell Research. 196:66-71
The expression of laminin chains was analyzed in normal and Ha-ras1-transformed rat liver epithelial cells. The normal, nontumorigenic cells were induced to migrate by epidermal growth factor, whereas the Ha-ras1-transformed, malignant derivatives mi
Autor:
Andrew J. Crossthwaite, Joachim E. Schultz, Nanako Masada, Kim Dufraux, Thomas Seebacher, Antonio Ciruela, Dermot M.F. Cooper
Publikováno v:
The Journal of biological chemistry. 280(8)
Lipid rafts are specialized, cholesterol-rich domains of the plasma membrane that are enriched in certain signaling proteins, including Ca(2+)-sensitive adenylyl cyclases. This restrictive localization plays a key role in the regulation of the Ca(2+)
Publikováno v:
Experimental cell research. 237(1)
The laminin family of extracellular matrix glycoproteins plays a major role in cell migration and differentiation and in tumor cell invasion. As previously shown, the laminin deposited by normal and malignant rat liver epithelial cells in their extra
Autor:
Ruthild G. Weber, Peter Lichter, Catherine Schurra, Christine Fischer, Thomas Seebacher, Jürgen Kraus, Anna Jauch, Aaron Bensimon, Thomas Cremer, Marion Cremer
Publikováno v:
Human genetics. 99(3)
Comparative genomic hybridization (CGH) has proven to be a comprehensive new tool to detect genetic imbalances in genomic DNA. However, the resolution of this method carried out on normal human metaphase spreads is limited to low copy number gains an
Publikováno v:
International Journal of Oncology.
The analysis of migration and gene expression patterns of normal and Ha-ras transformed rat liver epithelial cells revealed differences of diagnostic relevance. The normal cells are induced to migrate by EGF/TGF alpha and to express a set of secreted
Autor:
Ernesto G. Bade, Thomas Seebacher
Publikováno v:
Electrophoresis. 17:1573-1574
The program "molecular weights" allows a fast and easy estimation of molecular weights (M(r)), isoelectric point (pI) values and band intensities directly from scanned, polyacrylamide gels, two-dimensional protein patterns and DNA gel images. The ima