Zobrazeno 1 - 10
of 547
pro vyhledávání: '"Thomas Scheper"'
Autor:
Firat Baris Barlas, Bilge Olceroglu, Didem Ag Seleci, Zinar Pinar Gumus, Pinar Siyah, Meriam Dabbek, Georg Garnweitne, Frank Stahl, Thomas Scheper, Suna Timur
Publikováno v:
Cancer Medicine, Vol 13, Iss 15, Pp n/a-n/a (2024)
Abstract Background Cancer remains a formidable global health challenge, currently affecting nearly 20 million individuals worldwide. Due to the absence of universally effective treatments, ongoing research explores diverse strategies to combat this
Externí odkaz:
https://doaj.org/article/2a9fadbe70834f90b979fcd9ee8ccbbd
Autor:
Philipp Lindenhahn, Jannik Richter, Iliyana Pepelanova, Bettina Seeger, Holger A. Volk, Rabea Hinkel, Bernhard Hiebl, Thomas Scheper, Jan B. Hinrichs, Lena S. Becker, Axel Haverich, Tim Kaufeld
Publikováno v:
Biomimetics, Vol 9, Iss 4, p 197 (2024)
Background: Experimental coronary artery interventions are currently being performed on non-diseased blood vessels in healthy animals. To provide a more realistic pathoanatomical scenario for investigations on novel interventional and surgical therap
Externí odkaz:
https://doaj.org/article/d9332d5320c542b5bb60ba8d300ec901
Autor:
Ole Jacob Wohlenberg, Carlotta Kortmann, Katharina V. Meyer, Jana Schellenberg, Katharina Dahlmann, Janina Bahnemann, Thomas Scheper, Dörte Solle
Publikováno v:
Engineering in Life Sciences, Vol 22, Iss 7, Pp 484-494 (2022)
Abstract Quality by Design principles are well described and widely used in biopharmaceutical industry. The characterization of a monoclonal antibody (mAb) production process is crucial for novel process development and control. Yet, the application
Externí odkaz:
https://doaj.org/article/3b705c0b18ef4e1c8d7572e4e6844900
Autor:
Jana Schellenberg, Tamanna Nagraik, Ole Jacob Wohlenberg, Sebastian Ruhl, Janina Bahnemann, Thomas Scheper, Dörte Solle
Publikováno v:
Engineering in Life Sciences, Vol 22, Iss 5, Pp 427-436 (2022)
Abstract Monoclonal antibodies (mAbs) are of great interest to the biopharmaceutical industry due to their widely used application as human therapeutic and diagnostic agents. As such, mAb require to exhibit human‐like glycolization patterns. Theref
Externí odkaz:
https://doaj.org/article/e0eb90602f7643c1aa1a82f17f54975c
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 2, Pp n/a-n/a (2023)
Abstract Quality by Design (QbD) is one of the most important tools for the implementation of Process Analytical Technology (PAT) in biopharmaceutical production. For optimal characterization of a monoclonal antibody (mAb) upstream process a stepwise
Externí odkaz:
https://doaj.org/article/67c53fa960d54786ac1f684a20ecd154
Autor:
Sofia Arshavsky-Graham, Simon J. Ward, Naama Massad-Ivanir, Thomas Scheper, Sharon M. Weiss, Ester Segal
Publikováno v:
ACS Measurement Science Au, Vol 1, Iss 2, Pp 82-94 (2021)
Externí odkaz:
https://doaj.org/article/fafd49a92d2144a78295cd050f41b846
Autor:
Jana Schellenberg, Michaela Dehne, Ferdinand Lange, Thomas Scheper, Dörte Solle, Janina Bahnemann
Publikováno v:
Bioengineering, Vol 10, Iss 6, p 656 (2023)
Monoclonal antibodies are increasingly dominating the market for human therapeutic and diagnostic agents. For this reason, continuous methods—such as perfusion processes—are being explored and optimized in an ongoing effort to increase product yi
Externí odkaz:
https://doaj.org/article/93eb455b24164ed999817ca0455f50b8
Autor:
Katharina V. Meyer, Ina G. Siller, Jana Schellenberg, Alina Gonzalez Salcedo, Dörte Solle, Jens Matuszczyk, Thomas Scheper, Janina Bahnemann
Publikováno v:
Engineering in Life Sciences, Vol 21, Iss 5, Pp 288-293 (2021)
Abstract Due to the increasing economic and social relevance of biotherapeutics, their production processes are continually being reconsidered and reoptimized in an effort to secure higher product concentrations and qualities. Monitoring the producti
Externí odkaz:
https://doaj.org/article/c996d8c6c606436484514d4353f80b5f
Autor:
Ole Jacob Böhl, Jana Schellenberg, Janina Bahnemann, Bernd Hitzmann, Thomas Scheper, Dörte Solle
Publikováno v:
Engineering in Life Sciences, Vol 21, Iss 3-4, Pp 196-207 (2021)
Abstract The quality by design approach was introduced to the biopharmaceutical industry over 15 years ago. This principle is widely implemented in the characterization of monoclonal antibody production processes. Anyway, the early process phase, nam
Externí odkaz:
https://doaj.org/article/7ba3ca981e4542f5ab598160f9c3c1f2
Autor:
Marc Porr, Ferdinand Lange, Daniel Marquard, Laura Niemeyer, Patrick Lindner, Thomas Scheper, Sascha Beutel
Publikováno v:
Engineering in Life Sciences, Vol 21, Iss 3-4, Pp 208-219 (2021)
Abstract In this report, a fully integrated solution for laboratory digitization is presented. The approach presents a flexible and complete integration method for the digitally assisted workflow. The worker in the laboratory performs procedures in d
Externí odkaz:
https://doaj.org/article/65a40b74e3c8481abce03cb66c411b7a