Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Thomas S. Vedvick"'
Autor:
Amy R Noe, Diego Espinosa, Xiangming Li, Jordana G A Coelho-Dos-Reis, Ryota Funakoshi, Steve Giardina, Hongfan Jin, Diane M Retallack, Ryan Haverstock, Jeffrey R Allen, Thomas S Vedvick, Christopher B Fox, Steven G Reed, Ramses Ayala, Brian Roberts, Scott B Winram, John Sacci, Moriya Tsuji, Fidel Zavala, Gabriel M Gutierrez
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107764 (2014)
The circumsporozoite protein (CSP) of Plasmodium falciparum is a major surface protein, which forms a dense coat on the sporozoite's surface. Preclinical research on CSP and clinical evaluation of a CSP fragment-based RTS, S/AS01 vaccine have demonst
Externí odkaz:
https://doaj.org/article/3b2cec5996cd4a34b37c5b812f74c3d6
Autor:
Rhea N Coler, Sylvie Bertholet, Magdalini Moutaftsi, Jeff A Guderian, Hillarie Plessner Windish, Susan L Baldwin, Elsa M Laughlin, Malcolm S Duthie, Christopher B Fox, Darrick Carter, Martin Friede, Thomas S Vedvick, Steven G Reed
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16333 (2011)
Innate immune responses to vaccine adjuvants based on lipopolysaccharide (LPS), a component of gram-negative bacterial cell walls, are driven by Toll-like receptor (TLR) 4 and adaptor proteins including MyD88 and TRIF, leading to the production of in
Externí odkaz:
https://doaj.org/article/beb6c4c5d8824c4a9eada22324c31245
Autor:
Rhea N Coler, Susan L Baldwin, Narek Shaverdian, Sylvie Bertholet, Steven J Reed, Vanitha S Raman, Xiuhua Lu, Joshua DeVos, Kathy Hancock, Jacqueline M Katz, Thomas S Vedvick, Malcolm S Duthie, Christopher H Clegg, Neal Van Hoeven, Steven G Reed
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13677 (2010)
Safe, effective adjuvants that enhance vaccine potency, including induction of neutralizing Abs against a broad range of variant strains, is an important strategy for the development of seasonal influenza vaccines which can provide optimal protection
Externí odkaz:
https://doaj.org/article/55de1dba8ffc489da4c2d89e862f4a41
Autor:
Dawn M. Fedor, Quinton M. Dowling, Sylvain Cloutier, Sarah C. Parker, Michelle Archer, Lucien Barnes, Ryan M. Kramer, Thomas S. Vedvick, Simon Williams, Christopher B. Fox
Publikováno v:
AAPS PharmSciTech. 18:2077-2084
Although substantial effort has been made in the development of next-generation recombinant vaccine systems, maintenance of a cold chain is still typically required and remains a critical challenge in effective vaccine distribution. The ability to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aef1138a9ec814550a1088847a33be3
https://doi.org/10.1208/s12249-016-0688-7
https://doi.org/10.1208/s12249-016-0688-7
Autor:
Christopher B. Fox, Quinton M. Dowling, Michelle Archer, Dawn M. Fedor, Po-Wei D. Huang, Alicia M. Schwartz, Natasha Dubois Cauwelaert, Thomas S. Vedvick, Elyse A. Beebe, Mark T. Orr, Ryan M. Kramer
Publikováno v:
International Journal of Nanomedicine
Ryan M Kramer, Michelle C Archer, Mark T Orr, Natasha Dubois Cauwelaert, Elyse A Beebe, Po-wei D Huang, Quinton M Dowling, Alicia M Schwartz, Dawn M Fedor, Thomas S Vedvick, Christopher B Fox Infectious Disease Research Institute, Seattle, WA, USA Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4fba7f06d2f51415408295b031d995
https://pubmed.ncbi.nlm.nih.gov/29983563
https://pubmed.ncbi.nlm.nih.gov/29983563
Autor:
Laurentiu Berbecila, Vlad Tofan, Thomas S. Vedvick, Emilia Lupulescu, Chuong Huynh, Nicole L. Marlenee, Diana L. Noah, Susan L. Baldwin, Ene Vlase, Airn E. Hartwig, Neal Van Hoeven, Michael K. O’Hara, Crina Stavaru, Adrian Onu, Orhan Rasid, Christopher B. Fox, Helle Bielefeldt-Ohmann, Alina Ghiorghisor, Cristin Coman, Richard A. Bowen, Catalin Tucureanu, Iuliana Caras
Publikováno v:
Human Vaccines & Immunotherapeutics. 12:1009-1026
Millions of seasonal and pandemic influenza vaccine doses containing oil-in-water emulsion adjuvant have been administered in order to enhance and broaden immune responses and to facilitate antigen sparing. Despite the enactment of a Global Action Pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb43a42278358c0b25d067c129d7c514
https://doi.org/10.1080/21645515.2015.1111495
https://doi.org/10.1080/21645515.2015.1111495
Autor:
Quinton M. Dowling, Alicia M. Schwartz, Christopher B. Fox, Thomas S. Vedvick, Ryan M. Kramer
Publikováno v:
Journal of Pharmaceutical Sciences. 104:768-774
Aluminum salts have a long history as safe and effective vaccine adjuvants. In addition, aluminum salts have high adsorptive capacities for vaccine antigens and adjuvant molecules, for example, Toll-like receptor 4 (TLR4) agonists. However, the physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da6ed2d6d6052fb0b022f49555678aa
https://doi.org/10.1002/jps.24180
https://doi.org/10.1002/jps.24180
Autor:
Yevel Flores-Garcia, Steven G. Reed, Christian Muñoz, Chris J. Janse, Shahid M. Khan, Gabriel M. Gutierrez, Amy R. Noe, Randall F. Howard, Diane M. Retallack, Diego A. Espinosa, Fidel Zavala, Russell John Coleman, Christopher B. Fox, Alex Stevens, Joel Vega-Rodríguez, Thomas S. Vedvick, Torben Bruck, Ahmed M. Salman, Keith L. Haney, Jeffrey Allen
Publikováno v:
Infection and Immunity
Infection and Immunity, 85(2)
Infection and Immunity, 85(2)
Recent studies have shown that immune responses against the cell-traversal protein for Plasmodium ookinetes and sporozoites (CelTOS) can inhibit parasite infection. While these studies provide important evidence toward the development of vaccines tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d419f73d99b55fa0d8b74d12464bb932
https://hdl.handle.net/1887/96221
https://hdl.handle.net/1887/96221
Autor:
Rhea N. Coler, Christopher B. Fox, Quinton M. Dowling, Mark T. Orr, John D. Laurance, Steven G. Reed, Anthony L. Desbien, Thomas S. Vedvick, Ryan M. Kramer, Lucien Barnes, Elyse A. Beebe
Publikováno v:
Journal of Controlled Release. 177:20-26
Next-generation rationally-designed vaccine adjuvants represent a significant breakthrough to enable development of vaccines against challenging diseases including tuberculosis, HIV, and malaria. New vaccine candidates often require maintenance of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3051de4a6155463c5fbb2a1edf106858
https://doi.org/10.1016/j.jconrel.2013.12.025
https://doi.org/10.1016/j.jconrel.2013.12.025
Autor:
Jeff Guderian, James Chesko, Christopher B. Fox, Magdalini Moutaftsi, Quinton M. Dowling, Thomas S. Vedvick, Ryan M. Kramer, Sandra J. Sivananthan
Publikováno v:
Journal of Pharmaceutical Sciences. 103:879-889
Activity of adjuvanted vaccines is difficult to predict in vitro and in vivo. The wide compositional and conformational range of formulated adjuvants, from aluminum salts to oil-in-water emulsions, makes comparisons between physicochemical and immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7f1d619766951793a2a3635d569852
https://doi.org/10.1002/jps.23868
https://doi.org/10.1002/jps.23868