Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Thomas S. McConnell"'
Publikováno v:
Leukemia. 13:2007-2011
The Philadelphia chromosome translocation t(9;22)(q34;q11) may give rise to different BCR/ABL fusion mRNAs due to different genomic breakpoints and alternative splicing. The e1a2, b2a2 or b3a2 and c3a2 fusion mRNAs encode distinct fusion proteins (p1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70ae223d750761a4daeecba32ad0554
https://doi.org/10.1038/sj.leu.2401598
https://doi.org/10.1038/sj.leu.2401598
Publikováno v:
Journal of Pediatric Hematology/Oncology. 20:79-82
Purpose: We report a case of an isolated optic nerve relapse 3.5 years after diagnosis of hyperdiploid acute lymphoblastic leukemia (ALL) in a 6-year-old boy who had been off treatment for 3 months. The use of interphase fluorescence in situ hybridiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad41fa896aed1fc13abe2ffa049c93f0
https://doi.org/10.1097/00043426-199801000-00013
https://doi.org/10.1097/00043426-199801000-00013
Autor:
Kenneth J. Kopecky, Cheryl L. Willman, Marilyn L. Slovak, I-Ming Chen, Thomas S. McConnell, Catherine P. Leith, John E. Godwin, David R. Head, Frederick R. Appelbaum
Publikováno v:
Blood. 89:3323-3329
Compared with younger patients, elderly patients with acute myeloid leukemia (AML) respond poorly to conventional chemotherapy. To determine if this poor response is due to differences in the biologic characteristics of AML in the elderly, we studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66ac39a1768de8546f6577a30257ba2f
https://doi.org/10.1182/blood.v89.9.3323
https://doi.org/10.1182/blood.v89.9.3323
Autor:
Thomas S. McConnell, Everardo Cobos, Vijay S. Tonk, Dale M. Dunn, David Morgan, Yi-Kong Keung
Publikováno v:
Cancer Genetics and Cytogenetics. 92:50-53
We describe the first reported case of acute myelogenous leukemia with characteristics of megakaryoblastic differentiation and the t(15;17) chromosomal translocation, which has been associated with promyelocytic leukemia. The diagnostic, clinical, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd92b461ad6868486214cf2920f174c
https://doi.org/10.1016/s0165-4608(96)00158-6
https://doi.org/10.1016/s0165-4608(96)00158-6
Autor:
Richard M. Feddersen, Marilyn H. Duncan, Steven Brodie, Sandra J Stocker, Thomas S. McConnell, James C Wardlaw, Thomas M. Williams
Publikováno v:
Human Pathology. 26:1370-1374
Chromosome translocations found in neoplasms often result in the creation of hybrid genes encoding chimeric proteins. This case study describes a patient with desmoplastic small round cell tumor (DSRCT) of the abdomen, an aggressive neoplasm characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e4e9dc88d8d33f33a38dd68837b280
https://doi.org/10.1016/0046-8177(95)90303-8
https://doi.org/10.1016/0046-8177(95)90303-8
Publikováno v:
Cancer. 72:2033-2041
Background. Although flow cytometry (FCM) has become a widely used technique for the measurement of DNA content in solid tumors, the correlation of ploidy analysis by FCM with cytogenetic analysis (CGA) is not well described. The sensitivities of G-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ddfc4cfb62dbc2fcc2541e392bc599a
https://doi.org/10.1002/1097-0142(19930915)72:6<2033::aid-cncr2820720640>3.0.co
https://doi.org/10.1002/1097-0142(19930915)72:6<2033::aid-cncr2820720640>3.0.co
Autor:
Kent F. Argubright, Kathy Foucar, Gary Aisenbrey, Kenneth D. Friedman, Thomas S. McConnell, Amy Llewellyn, Lori Ballinger
Publikováno v:
American Journal of Clinical Pathology. 97:584-590
Since its initial description in 1982, percutaneous umbilical blood sampling has become useful in diagnosing, monitoring, and even treating a variety of fetal disorders. Recently two percutaneous umbilical blood samples were evaluated in which the wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4e721d5851063685fe8c1dbe500b60
https://doi.org/10.1093/ajcp/97.4.584
https://doi.org/10.1093/ajcp/97.4.584
Publikováno v:
Journal of Maternal-Fetal and Neonatal Medicine. 1:234-238
CA 125 levels have been measured in the amniotic fluid of 86 gravidas between 14 and 20 weeks gestation as well as in 18 women at term, all carrying chromosomally normal fetuses; in 36 gestations, the samples were paired with maternal serum specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b1c899c8060e6e1672ac96ef961b41
https://doi.org/10.3109/14767059209161924
https://doi.org/10.3109/14767059209161924
Publikováno v:
American Journal of Obstetrics and Gynecology. 165:1419-1422
Recombinant 8 syndrome is a well-established syndrome with mental and developmental retardation and usually severe cardiac anomalies. A carrier parent will produce affected offspring in 6% of pregnancies and carrier offspring in 53% of such pregnanci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d5873490baaca366ffcb05f479d80
https://doi.org/10.1016/s0002-9378(12)90776-0
https://doi.org/10.1016/s0002-9378(12)90776-0
Publikováno v:
Cancer Genetics and Cytogenetics. 53:257-263
The biologic significance of clonal karyotypic abnormalities in human neoplasms is becoming better understood, but the significance of rare chromosomal aberrations is uncertain. Useful, yet arbitrary, cytogenetic definitions of a clone have been esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf26f7acfc827b45a855a0448c672a14
https://doi.org/10.1016/0165-4608(91)90102-z
https://doi.org/10.1016/0165-4608(91)90102-z