Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Thomas S. Kickler"'
Autor:
Ping Chen MD, PhD, Jayesh Jani MS, Michael B. Streiff MD, Gang Zheng MD, PhD, Thomas S. Kickler MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 25 (2019)
Global hemostatic assays including thromboelastography (TEG), Innovance ETP (endogenous thrombin potential), and Thrombinoscope could measure thrombin generation potential and be useful to guide management of patients with factor VIII (FVIII) inhibit
Externí odkaz:
https://doaj.org/article/7eff9ed9cfcf4dcfb6767684fc531840
Autor:
Nikolaos Kakouros, Tyler J. Gluckman, John V. Conte, Thomas S. Kickler, Katherine Laws, Bruce A. Barton, Jeffrey J. Rade
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundSystemic thromboxane generation, not suppressible by standard aspirin therapy and likely arising from nonplatelet sources, increases the risk of atherothrombosis and death in patients with cardiovascular disease. In the RIGOR (Reduction in
Externí odkaz:
https://doaj.org/article/e8ea9913d0b64fdca29648a2c98872e4
Autor:
Jacopo Biasetti, Kaushik Sampath, Angel Cortez, Alaleh Azhir, Assaf A. Gilad, Thomas S. Kickler, Tobias Obser, Zaverio M. Ruggeri, Joseph Katz
Publikováno v:
International Journal of Biomedical Imaging, Vol 2017 (2017)
Tracking cells and proteins’ phenotypic changes in deep suspensions is critical for the direct imaging of blood-related phenomena in in vitro replica of cardiovascular systems and blood-handling devices. This paper introduces fluorescence imaging t
Externí odkaz:
https://doaj.org/article/bfd9fc4082b840e7be01e1bdacd5e5b1
Autor:
Nikolaos Kakouros, Susanna M. Nazarian, Patrizia B. Stadler, Thomas S. Kickler, Jeffrey J. Rade
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 3 (2016)
BackgroundPersistent thromboxane (TX) generation while receiving aspirin therapy is associated with an increased risk of cardiovascular events. The Reduction in Graft Occlusion Rates (RIGOR) study found that aspirin‐insensitive TXA2 generation, ind
Externí odkaz:
https://doaj.org/article/1a5105d4c0b7474bbbf3194c47b99ae2
Autor:
Nicholas B. Abt, Michael B. Streiff, Christian B. Gocke, Thomas S. Kickler, Sophie M. Lanzkron
Publikováno v:
Case Reports in Hematology, Vol 2014 (2014)
Objective. We present the case of a 73-year-old female, with no family or personal history of a bleeding disorder, who had a classic presentation for acquired hemophilia A. Factor VIII activity was low but detectable and a factor VIII inhibitor was u
Externí odkaz:
https://doaj.org/article/0d4302f8641141009780a6d07f8b714b
Autor:
Qingbo Liu, Huiyi Miao, Shuai Li, Peng Zhang, Gloria F. Gerber, Dean Follmann, Hongkai Ji, Scott L. Zeger, Daniel S. Chertow, Thomas C. Quinn, Matthew L. Robinson, Thomas S. Kickler, Richard E. Rothman, Katherine Z. J. Fenstermacher, Evan M. Braunstein, Andrea L. Cox, Patrizia Farci, Anthony S. Fauci, Paolo Lusso
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Severe COVID-19 is characterized by a prothrombotic state associated with thrombocytopenia, with microvascular thrombosis being almost invariably present in the lung and other organs at postmortem examination. We evaluated the presence of antibodies
Autor:
Richard Wang, Yu Hsiang Hsieh, Danna Anderson, Eshan U. Patel, Ethan Klock, Jennifer Hurley, Richard E. Rothman, Oliver Laeyendecker, Morgan Keruly, Mehdi Youbi, Gabor D. Kelen, Yolanda Eby, Isabel V. Lake, Charles S. Kirby, Owen R Baker, Jernelle Miller, Thomas S. Kickler, Ross Knaub, William Clarke, Reinaldo E Fernandez, Haley A Schmidt, Thomas C. Quinn, Momina Khan, Sarah Reineck, Erin P. Ricketts, Aaron A.R. Tobian, Gaby Dashler
Publikováno v:
The American Journal of Emergency Medicine
Background Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the
Publikováno v:
The American Journal of Medicine
Background Cytokines seen in severe coronavirus disease 2019 (COVID-19) are associated with proliferation, differentiation, and survival of plasma cells. Plasma cells are not routinely found in peripheral blood, though may produce virus-neutralizing
Autor:
Thomas S. Kickler, Rakhi P. Naik, Michael B. Streiff, John Lindsley, Kathryn Dane, Shruti Chaturvedi, Jennifer Yui, Alison R. Moliterno
Publikováno v:
Blood Adv
Acquired von Willebrand disease (aVWD) is a rare disorder associated with a reduction in von Willebrand factor (VWF) activity, leading to increased bleeding risk. Monoclonal gammopathy of undetermined significance (MGUS) is the most common cause of l
Autor:
Thomas S. Kickler, David A. Bluemke, Hong Lai, Shaoguang Chen, Raul N. Mandler, Shenghan Lai, Márton Kolossváry, Gary Gerstenblith, Sandeepan Bhatia, Elliot K. Fishman
Publikováno v:
Radiology
BACKGROUND: Various cardiovascular risk factors are thought to modify atherosclerosis in a similar fashion (ie, by increasing the magnitude of coronary artery disease [CAD]). However, coronary CT angiography allows precision phenotyping of plaque cha