Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thomas S. Elliott"'
Autor:
Sebastian Kehrloesser, Oliver Cast, Thomas S Elliott, Russell J Ernst, Anne C Machel, Jia-Xuan Chen, Jason W Chin, Martin L Miller
Publikováno v:
PNAS Nexus. 2
The ability to assign cellular origin to low-abundance secreted factors in extracellular vesicles (EVs) would greatly facilitate the analysis of paracrine-mediated signaling. Here, we report a method, named selective isolation of extracellular vesicl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c926239263ee00f1ff21e6afc28061c4
https://doi.org/10.1093/pnasnexus/pgad107
https://doi.org/10.1093/pnasnexus/pgad107
Publikováno v:
Genes and Development
3’-end processing of most human mRNAs is carried out by the cleavage and polyadenylation specificity factor (CPSF; CPF in yeast). Endonucleolytic cleavage of the nascent pre-mRNA defines the 3’-end of the mature transcript, which is important for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1238549b4ecefe5f82e054bfb2c14093
https://doi.org/10.1101/gad.349223.121
https://doi.org/10.1101/gad.349223.121
Autor:
Martin Spinck, Carlos Piedrafita, Wesley E. Robertson, Thomas S. Elliott, Daniele Cervettini, Daniel de la Torre, Jason W. Chin
The direct genetically encoded cell-based synthesis of non-natural peptide and depsipeptide macrocycles is an outstanding challenge. Here we programme the encoded synthesis of 25 diverse non-natural macrocyclic peptides, each containing two non-canon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68756d212882bdba2c1cba0d27cf432
https://www.repository.cam.ac.uk/handle/1810/345723
https://www.repository.cam.ac.uk/handle/1810/345723
Autor:
Jérôme F. Zürcher, Wesley E. Robertson, Tomás Kappes, Gianluca Petris, Thomas S. Elliott, George P. C. Salmond, Jason W. Chin
Publikováno v:
Science
The near-universal genetic code defines the correspondence between codons in genes and amino acids in proteins. We refactored the structure of the genetic code in Escherichia coli and created orthogonal genetic codes that restrict the escape of synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193152864efde9469162ef393b8ac61a
https://europepmc.org/articles/PMC7614150/
https://europepmc.org/articles/PMC7614150/
Autor:
Sarah L. Maslen, Salvador Buse, Martin Spinck, Louise F. H. Funke, Daniel de la Torre, George P. C. Salmond, Wesley E. Robertson, Thomas S. Elliott, Franz L. Böge, Daniele Cervettini, Julius Fredens, Jason W. Chin, Yonka Christova, Kim C. Liu
Publikováno v:
Science. 372:1057-1062
Designing bacterial superpowers Biological systems read all 64 triplet codons in DNA to encode the synthesis of proteins composed of 20 canonical amino acids. Robertson et al. created cells that do not read several codons and showed that this confers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f1add2abd9e8d7046f897f7ff53b62
https://doi.org/10.1126/science.abg3029
https://doi.org/10.1126/science.abg3029
Autor:
Martin, Spinck, Carlos, Piedrafita, Wesley E, Robertson, Thomas S, Elliott, Daniele, Cervettini, Daniel, de la Torre, Jason W, Chin
Publikováno v:
Nature chemistry.
The direct genetically encoded cell-based synthesis of non-natural peptide and depsipeptide macrocycles is an outstanding challenge. Here we programme the encoded synthesis of 25 diverse non-natural macrocyclic peptides, each containing two non-canon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::517a738e0b9a7b1fd417053bb831d354
https://pubmed.ncbi.nlm.nih.gov/36550233
https://pubmed.ncbi.nlm.nih.gov/36550233
Publikováno v:
Cell Chemical Biology. 23(7):805-815
SummaryCell-specific proteomics in multicellular systems and whole animals is a promising approach to understand the differentiated functions of cells and tissues. Here, we extend our stochastic orthogonal recoding of translation (SORT) approach for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41a4b980d79f6f57ef009cf5085d0f7
Autor:
Václav Beránek, Yonka Christova, Daniel L. Dunkelmann, Tiongsun Chia, Andres Gonzalez Llamazares, Chayasith Uttamapinant, Louise F. H. Funke, Daniel de la Torre, Wolfgang H. Schmied, Jason W. Chin, Kaihang Wang, Julius Fredens, Wesley E. Robertson, Thomas S. Elliott
Publikováno v:
Nature. 569(7757)
Nature uses 64 codons to encode the synthesis of proteins from the genome, and chooses 1 sense codon—out of up to 6 synonyms—to encode each amino acid. Synonymous codon choice has diverse and important roles, and many synonymous substitutions are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec1c257e12c4164e93dffe910e1e67e
https://pubmed.ncbi.nlm.nih.gov/31097820
https://pubmed.ncbi.nlm.nih.gov/31097820
Autor:
Václav Beránek, Johanna E. Chesham, Thomas S. Elliott, Toke P. Krogager, Russell J. Ernst, Elizabeth S. Maywood, Marco Brancaccio, Michael H. Hastings, Jason W. Chin, Andrew P. Patton
Publikováno v:
E12397
E12388
E12388
The suprachiasmatic nucleus (SCN) is the principal circadian clock of mammals, coordinating daily rhythms of physiology and behavior. Circadian timing pivots around self-sustaining transcriptional–translational negative feedback loops (TTFLs), wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4ba02d9a8ac08a5932361a36c61e3f
https://doi.org/10.1073/pnas.1811438115
https://doi.org/10.1073/pnas.1811438115
Publikováno v:
Biophysical Journal. 116:360a-361a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b83bc92a94b16bbe9e6bddf17d3de03
https://doi.org/10.1016/j.bpj.2018.11.1963
https://doi.org/10.1016/j.bpj.2018.11.1963