Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Thomas S Kickler"'
Autor:
Santhi K Ganesh, Yugal Sharma, Judith Dayhoff, Henry M Fales, Jennifer Van Eyk, Thomas S Kickler, Eric M Billings, Elizabeth G Nabel
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e544 (2007)
Available blood assays for venous thromboembolism (VTE) suffer from diminished specificity. Compared with single marker tests, such as D-dimer, a multi-marker strategy may improve diagnostic ability. We used direct mass spectrometry (MS) analysis of
Externí odkaz:
https://doaj.org/article/97c43baee737435cbfd3469343045b72
Autor:
Ivo M.B. Francischetti, Kevin Toomer, Yifan Zhang, Jayesh Jani, Zishan Siddiqui, Daniel J. Brotman, Jody E. Hooper, Thomas S. Kickler
Publikováno v:
EClinicalMedicine, Vol 39, Iss , Pp 101069- (2021)
Background: SARS-CoV-2 infection is associated with thrombotic and microvascular complications. The cause of coagulopathy in the disease is incompletely understood. Methods: A single-center cross-sectional study including 66 adult COVID-19 patients (
Externí odkaz:
https://doaj.org/article/b17b1d0611c3414abfb5f9cf23033c62
Autor:
Qingbo Liu, Huiyi Miao, Shuai Li, Peng Zhang, Gloria F. Gerber, Dean Follmann, Hongkai Ji, Scott L. Zeger, Daniel S. Chertow, Thomas C. Quinn, Matthew L. Robinson, Thomas S. Kickler, Richard E. Rothman, Katherine Z. J. Fenstermacher, Evan M. Braunstein, Andrea L. Cox, Patrizia Farci, Anthony S. Fauci, Paolo Lusso
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Severe COVID-19 is characterized by a prothrombotic state associated with thrombocytopenia, with microvascular thrombosis being almost invariably present in the lung and other organs at postmortem examination. We evaluated the presence of antibodies
Autor:
Nikolaos Kakouros, Tyler J. Gluckman, John V. Conte, Thomas S. Kickler, Katherine Laws, Bruce A. Barton, Jeffrey J. Rade
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundSystemic thromboxane generation, not suppressible by standard aspirin therapy and likely arising from nonplatelet sources, increases the risk of atherothrombosis and death in patients with cardiovascular disease. In the RIGOR (Reduction in
Externí odkaz:
https://doaj.org/article/e8ea9913d0b64fdca29648a2c98872e4
Autor:
Richard Wang, Yu Hsiang Hsieh, Danna Anderson, Eshan U. Patel, Ethan Klock, Jennifer Hurley, Richard E. Rothman, Oliver Laeyendecker, Morgan Keruly, Mehdi Youbi, Gabor D. Kelen, Yolanda Eby, Isabel V. Lake, Charles S. Kirby, Owen R Baker, Jernelle Miller, Thomas S. Kickler, Ross Knaub, William Clarke, Reinaldo E Fernandez, Haley A Schmidt, Thomas C. Quinn, Momina Khan, Sarah Reineck, Erin P. Ricketts, Aaron A.R. Tobian, Gaby Dashler
Publikováno v:
The American Journal of Emergency Medicine
Background Emergency Departments (EDs) have served as critical surveillance sites for infectious diseases. We sought to determine the prevalence and temporal trends of acute (by PCR) and convalescent (by antibody [Ab]) SARS-CoV-2 infection during the
Publikováno v:
The American Journal of Medicine
Background Cytokines seen in severe coronavirus disease 2019 (COVID-19) are associated with proliferation, differentiation, and survival of plasma cells. Plasma cells are not routinely found in peripheral blood, though may produce virus-neutralizing
Autor:
Thomas S. Kickler, Rakhi P. Naik, Michael B. Streiff, John Lindsley, Kathryn Dane, Shruti Chaturvedi, Jennifer Yui, Alison R. Moliterno
Publikováno v:
Blood Adv
Acquired von Willebrand disease (aVWD) is a rare disorder associated with a reduction in von Willebrand factor (VWF) activity, leading to increased bleeding risk. Monoclonal gammopathy of undetermined significance (MGUS) is the most common cause of l
Autor:
Thomas S. Kickler, David A. Bluemke, Hong Lai, Shaoguang Chen, Raul N. Mandler, Shenghan Lai, Márton Kolossváry, Gary Gerstenblith, Sandeepan Bhatia, Elliot K. Fishman
Publikováno v:
Radiology
BACKGROUND: Various cardiovascular risk factors are thought to modify atherosclerosis in a similar fashion (ie, by increasing the magnitude of coronary artery disease [CAD]). However, coronary CT angiography allows precision phenotyping of plaque cha
Autor:
Nikolaos Kakouros, Susanna M. Nazarian, Patrizia B. Stadler, Thomas S. Kickler, Jeffrey J. Rade
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 3 (2016)
BackgroundPersistent thromboxane (TX) generation while receiving aspirin therapy is associated with an increased risk of cardiovascular events. The Reduction in Graft Occlusion Rates (RIGOR) study found that aspirin‐insensitive TXA2 generation, ind
Externí odkaz:
https://doaj.org/article/1a5105d4c0b7474bbbf3194c47b99ae2
Publikováno v:
Angew Chem Int Ed Engl
In this study, we propose the use of surface-enhanced Raman spectroscopy (SERS) to determine spectral markers for recognition of heparin-induced thrombocytopenia (HIT), a difficult-to-diagnose immune-related complication that often leads to limb isch