Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Thomas Riediger"'
Autor:
Kathrin Abegg, Andreas Hermann, Christina N. Boyle, Sebastien G. Bouret, Thomas A. Lutz, Thomas Riediger
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
The area postrema (AP) and the nucleus of the solitary tract (NTS) are important hindbrain centers involved in the control of energy homeostasis. The AP mediates the anorectic action and the inhibitory effect on gastric emptying induced by the pancre
Externí odkaz:
https://doaj.org/article/0115a7b3741e4bc39a4b7608f8ae2d95
Autor:
Tito Borner, Johan Ruud, Thomas A. Lutz, Thomas Riediger, Myrtha Arnold, Anders Blomqvist, Samuel N. Breit, Wolfgang Langhans
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 8:417-427
BACKGROUND: The cancer-anorexia-cachexia syndrome (CACS) negatively affects survival and therapy success in cancer patients. Inflammatory mediators and tumour-derived factors are thought to play an important role in the aetiology of CACS. However, th
Publikováno v:
Neuropharmacology. 180:108289
Up to 80% of cancer patients are affected by the cancer anorexia-cachexia syndrome (CACS), which leads to excessive body weight loss, reduced treatment success and increased lethality. The area postrema/nucleus of the solitary tract (AP/NTS) region e
Publikováno v:
Neuropharmacology. 131
The cancer anorexia-cachexia syndrome (CACS) is a frequent and severe condition in cancer patients. Currently, no pharmacological treatment is approved for the therapy of CACS. Centrally, glucagon-like peptide-1 (GLP-1) is expressed in the nucleus tr
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 5; Pages: 986
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The gastrointestinal hormone ghrelin reduces energy expenditure and stimulates food intake. Ghrelin analogs are a possible treatment against cancer anorexia-cachexia syndrome (CACS). This study aimed to investigate whether oral treatment with the non
Autor:
Melanie Hutter, Lara Bernasconi, Claudio Pietra, Thomas A. Lutz, Thomas Riediger, Kathrin Abegg, Claudio Giuliano, Lynda Whiting
Publikováno v:
Diabetes, obesitymetabolism. 19(12)
Aims Ghrelin is implicated in the control of energy balance and glucose homeostasis. The ghrelin receptor exhibits ligand independent constitutive activity, which can be pharmacologically exploited to induce inverse ghrelin actions. Since ghrelin rec
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 311(1)
The gastric hormone ghrelin positively affects energy balance by increasing food intake and reducing energy expenditure. Ghrelin mimetics are a possible treatment against cancer anorexia-cachexia syndrome (CACS). This study aimed to characterize the
Autor:
Victoria F. Turek, Barbara L. Roland, Thomas A. Lutz, Calvin Vu, Thomas Riediger, Catarina Soares Potes, Rebecca L. Cole, Jonathan D. Roth
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 299:R623-R631
Circulating amylin inhibits food intake via activation of the area postrema (AP). The aim of this study was to identify the neurochemical phenotype of the neurons mediating amylin's hypophagic action by immunohistochemical and feeding studies in rats
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 299:R632-R641
Fasting increases c-Fos expression in neuropeptide Y (NPY) neurons of the hypothalamic arcuate nucleus (ARC) in lean, but not in hyperleptinemic mice with late-onset obesity (LOO). Although obesity is associated with leptin resistance, we hypothesize
Publikováno v:
Brain Research. 1334:31-44
The ability of the pancreatic hormone amylin to inhibit food intake relies on a direct activation of the area postrema (AP). This activation is synaptically transmitted to the nucleus of the solitary tract (NTS), the lateral parabrachial nucleus (LPB