Opioids, microglia, and temporal lobe epilepsy

Autor: Lauren Marijke Lankhuijzen, Thomas Ridler

Publikováno v: Frontiers in Neurology, Vol 14 (2024)

A lack of treatment options for temporal lobe epilepsy (TLE) demands an urgent quest for new therapies to recover neuronal damage and reduce seizures, potentially interrupting the neurotoxic cascades that fuel hyper-excitability. Endogenous opioids,

Externí odkaz: https://doaj.org/article/0fb5e3c19d944fb184de7b1278153a31

Impaired speed encoding and grid cell periodicity in a mouse model of tauopathy

Autor: Thomas Ridler, Jonathan Witton, Keith G Phillips, Andrew D Randall, Jonathan T Brown

Publikováno v: eLife, Vol 9 (2020)

Dementia is associated with severe spatial memory deficits which arise from dysfunction in hippocampal and parahippocampal circuits. For spatially sensitive neurons, such as grid cells, to faithfully represent the environment these circuits require p

Externí odkaz: https://doaj.org/article/71ee70328f8f4fac9d68cfea99aae63d

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3

Autor: Adam J. H. Newton, Alexandra H. Seidenstein, Robert A. McDougal, Alberto Pérez-Cervera, Gemma Huguet, Tere M-Seara, Caroline Haimerl, David Angulo-Garcia, Alessandro Torcini, Rosa Cossart, Arnaud Malvache, Kaoutar Skiker, Mounir Maouene, Gianmarco Ragognetti, Letizia Lorusso, Andrea Viggiano, Angelo Marcelli, Rosa Senatore, Antonio Parziale, S. Stramaglia, M. Pellicoro, L. Angelini, E. Amico, H. Aerts, J. Cortés, S. Laureys, D. Marinazzo, I. Bassez, L. Faes, Hannes Almgren, Adeel Razi, Frederik Van de Steen, Ruth Krebs, Hannelore Aerts, Lida Kanari, Pawel Dlotko, Martina Scolamiero, Ran Levi, Julian Shillcock, Christiaan P.J. de Kock, Kathryn Hess, Henry Markram, Cheng Ly, Gary Marsat, Tom Gillespie, Malin Sandström, Mathew Abrams, Jeffrey S. Grethe, Maryann Martone, Robin De Gernier, Sergio Solinas, Christian Rössert, Marc Haelterman, Serge Massar, Valentina Pasquale, Vito Paolo Pastore, Sergio Martinoia, Paolo Massobrio, Cristiano Capone, Núria Tort-Colet, Maria V. Sanchez-Vives, Maurizio Mattia, Ali Almasi, Shaun L. Cloherty, David B. Grayden, Yan T. Wong, Michael R. Ibbotson, Hamish Meffin, Luke Y. Prince, Krasimira Tsaneva-Atanasova, Jack R. Mellor, Alberto Mazzoni, Manuela Rosa, Jacopo Carpaneto, Luigi M. Romito, Alberto Priori, Silvestro Micera, Rosanna Migliore, Carmen Alina Lupascu, Francesco Franchina, Luca Leonardo Bologna, Armando Romani, Sára Saray, Werner Van Geit, Szabolcs Káli, Alex Thomson, Audrey Mercer, Sigrun Lange, Joanne Falck, Eilif Muller, Felix Schürmann, Dmitrii Todorov, Robert Capps, William Barnett, Yaroslav Molkov, Federico Devalle, Diego Pazó, Ernest Montbrió, Gabriela Mochol, Habiba Azab, Benjamin Y. Hayden, Rubén Moreno-Bote, Pragathi Priyadharsini Balasubramani, Srinivasa V. Chakravarthy, Vignayanandam R. Muddapu, Medorian D. Gheorghiu, Bartul Mimica, Jonathan Withlock, Raul C. Mureșan, Jennifer L. Zick, Kelsey Schultz, Rachael K. Blackman, Matthew V. Chafee, Theoden I. Netoff, Nicholas Roberts, Vivek Nagaraj, Andrew Lamperski, Logan L. Grado, Matthew D. Johnson, David P. Darrow, Davide Lonardoni, Hayder Amin, Stefano Di Marco, Alessandro Maccione, Luca Berdondini, Thierry Nieus, Marcel Stimberg, Dan F. M. Goodman, Thomas Nowotny, Veronika Koren, Valentin Dragoi, Klaus Obermayer, Samy Castro, Mariano Fernandez, Wael El-Deredy, Kesheng Xu, Jean Paul Maidana, Patricio Orio, Weiliang Chen, Iain Hepburn, Francesco Casalegno, Adrien Devresse, Aleksandr Ovcharenko, Fernando Pereira, Fabien Delalondre, Erik De Schutter, Peter Bratby, Andrew R. Gallimore, Guido Klingbeil, Criseida Zamora, Yunliang Zang, Patrick Crotty, Eric Palmerduca, Alberto Antonietti, Claudia Casellato, Csaba Erö, Egidio D’Angelo, Marc-Oliver Gewaltig, Alessandra Pedrocchi, Ilja Bytschok, Dominik Dold, Johannes Schemmel, Karlheinz Meier, Mihai A. Petrovici, Hui-An Shen, Simone Carlo Surace, Jean-Pascal Pfister, Baptiste Lefebvre, Olivier Marre, Pierre Yger, Athanasia Papoutsi, Jiyoung Park, Ryan Ash, Stelios Smirnakis, Panayiota Poirazi, Richard A. Felix, Alexander G. Dimitrov, Christine Portfors, Silvia Daun, Tibor I. Toth, Joanna Jędrzejewska-Szmek, Nadine Kabbani, Kim T. Blackwel, Bahar Moezzi, Natalie Schaworonkow, Lukas Plogmacher, Mitchell R. Goldsworthy, Brenton Hordacre, Mark D. McDonnell, Nicolangelo Iannella, Michael C. Ridding, Jochen Triesch, Reinoud Maex, Karen Safaryan, Volker Steuber, Rongxiang Tang, Yi-Yuan Tang, Darya V. Verveyko, Alexey R. Brazhe, Andrey Yu Verisokin, Dmitry E. Postnov, Cengiz Günay, Gabriella Panuccio, Michele Giugliano, Astrid A. Prinz, Pablo Varona, Mikhail I. Rabinovich, Jack Denham, Thomas Ranner, Netta Cohen, Maria Reva, Nelson Rebola, Tekla Kirizs, Zoltan Nusser, David DiGregorio, Eirini Mavritsaki, Panos Rentzelas, Nikul H. Ukani, Adam Tomkins, Chung-Heng Yeh, Wesley Bruning, Allison L. Fenichel, Yiyin Zhou, Yu-Chi Huang, Dorian Florescu, Carlos Luna Ortiz, Paul Richmond, Chung-Chuan Lo, Daniel Coca, Ann-Shyn Chiang, Aurel A. Lazar, Jennifer L. Creaser, Congping Lin, Peter Ashwin, Jonathan T. Brown, Thomas Ridler, Daniel Levenstein, Brendon O. Watson, György Buzsáki, John Rinzel, Rodica Curtu, Anh Nguyen, Sahand Assadzadeh, Peter A. Robinson, Paula Sanz-Leon, Caroline G. Forlim, Lírio O. B. de Almeida, Reynaldo D. Pinto, Francisco B. Rodríguez, Ángel Lareo, Caroline Garcia Forlim, Aaron Montero, Thiago Mosqueiro, Ramon Huerta, Francisco B. Rodriguez, Vinicio Changoluisa, Vinícius L. Cordeiro, César C. Ceballos, Nilton L. Kamiji, Antonio C. Roque, William W. Lytton, Andrew Knox, Joshua J. C. Rosenthal, Svitlana Popovych, Liqing Liu, Bin A. Wang, Tibor I. Tóth, Christian Grefkes, Gereon R. Fink, Nils Rosjat, Abraham Perez-Trujillo, Andres Espinal, Marco A. Sotelo-Figueroa, Ivan Cruz-Aceves, Horacio Rostro-Gonzalez, Martin Zapotocky, Martina Hoskovcová, Jana Kopecká, Olga Ulmanová, Evžen Růžička, Matthias Gärtner, Sevil Duvarci, Jochen Roeper, Gaby Schneider, Stefan Albert, Katharina Schmack, Michiel Remme, Susanne Schreiber, Michele Migliore, Carmen A. Lupascu, Luca L. Bologna, Stefano M. Antonel, Jean-Denis Courcol, Sami Utku Çelikok, Eva M. Navarro-López, Neslihan Serap Şengör, Rahmi Elibol, Neslihan Serap Sengor, Mustafa Yasir Özdemir, Tianyi Li, Angelo Arleo, Denis Sheynikhovich, Akihiro Nakamura, Masanori Shimono, Youngjo Song, Sol Park, Ilhwan Choi, Jaeseung Jeong, Hee-sup Shin, Sadra Sadeh, Padraig Gleeson, R. Angus Silver, Alexandra Pierri Chatzikalymniou, Frances K. Skinner, Lazaro M. Sanchez-Rodriguez, Roberto C. Sotero, Loreen Hertäg, Owen Mackwood, Henning Sprekeler, Steffen Puhlmann, Simon N. Weber, David Higgins, Laura B. Naumann, Ramakrisnan Iyer, Stefan Mihalas, Valentina Ticcinelli, Tomislav Stankovski, Peter V. E. McClintock, Aneta Stefanovska, Predrag Janjić, Dimitar Solev, Gerald Seifert, Ljupčo Kocarev, Christian Steinhäuser, Mehrdad Salmasi, Stefan Glasauer, Martin Stemmler, Danke Zhang, Chi Zhang, Armen Stepanyants, Julia Goncharenko, Lieke Kros, Neil Davey, Chris de Zeeuw, Freek Hoebeek, Ankur Sinha, Roderick Adams, Michael Schmuker, Maria Psarrou, Maria Schilstra, Benjamin Torben-Nielsen, Christoph Metzner, Achim Schweikard, Tuomo Mäki-Marttunen, Bartosz Zurowski, Daniele Marinazzo, Luca Faes, Sebastiano Stramaglia, Henry O. C. Jordan, Simon M. Stringer, Elżbieta Gajewska-Dendek, Piotr Suffczyński, Nicoladie Tam, George Zouridakis, Luca Pollonini, Mojtaba Madadi Asl, Alireza Valizadeh, Peter A. Tass, Andreas Nold, Wei Fan, Sara Konrad, Heiko Endle, Johannes Vogt, Tatjana Tchumatchenko, Juliane Herpich, Christian Tetzlaff, Jannik Luboeinski, Timo Nachstedt, Manuel Ciba, Andreas Bahmer, Christiane Thielemann, Eric S. Kuebler, Joseph S. Tauskela, Jean-Philippe Thivierge, Rembrandt Bakker, María García-Amado, Marian Evangelio, Francisco Clascá, Paul Tiesinga, Christopher L. Buckley, Taro Toyoizumi, Alexis M. Dubreuil, Rémi Monasson, Alessandro Treves, Davide Spalla, Sophie Rosay, Florence I. Kleberg, Willy Wong, Bruno de Oliveira Floriano, Toshihiko Matsuo, Tetsuya Uchida, Domenica Dibenedetto, Kâmil Uludağ, Abdorreza Goodarzinick, Maximilian Schmidt, Claus C. Hilgetag, Markus Diesmann, Sacha J. van Albada, Michael Fauth, Mark van Rossum, Manuel Reyes-Sánchez, Rodrigo Amaducci, Carlos Muñiz, Irene Elices, David Arroyo, Rafael Levi, Ben Cohen, Carson Chow, Shashaank Vattikuti, Elena Bertolotti, Raffaella Burioni, Matteo di Volo, Alessandro Vezzani, Bayar Menzat, Tim P. Vogels, Nobuhiko Wagatsuma, Susmita Saha, Reena Kapoor, Robert Kerr, John Wagner, Luis C. Garcia del Molino, Guangyu Robert Yang, Jorge F. Mejias, Xiao-Jing Wang, Hanbing Song, Joseph Goodliffe, Jennifer Luebke, Christina M. Weaver, John Thomas, Nishant Sinha, Nikhita Shaju, Tomasz Maszczyk, Jing Jin, Sydney S. Cash, Justin Dauwels, M. Brandon Westover, Maryam Karimian, Michelle Moerel, Peter De Weerd, Thomas Burwick, Ronald L. Westra, Romesh Abeysuriya, Jonathan Hadida, Stamatios Sotiropoulos, Saad Jbabdi, Mark Woolrich, Chama Bensmail, Borys Wrobel, Xiaolong Zhou, Zilong Ji, Xiao Liu, Yan Xia, Si Wu, Xiao Wang, Mingsha Zhang, Netanel Ofer, Orit Shefi, Gur Yaari, Ted Carnevale, Amit Majumdar, Subhashini Sivagnanam, Kenneth Yoshimoto, Elena Y. Smirnova, Dmitry V. Amakhin, Sergey L. Malkin, Aleksey V. Zaitsev, Anton V. Chizhov, Margarita Zaleshina, Alexander Zaleshin, Victor J. Barranca, George Zhu, Quinton M. Skilling, Daniel Maruyama, Nicolette Ognjanovski, Sara J. Aton, Michal Zochowski, Jiaxing Wu, Sara Aton, Scott Rich, Victoria Booth, Maral Budak, Salvador Dura-Bernal, Samuel A. Neymotin, Benjamin A. Suter, Gordon M. G. Shepherd, Melvin A. Felton, Alfred B. Yu, David L. Boothe, Kelvin S. Oie, Piotr J. Franaszczuk, Sergey A. Shuvaev, Batuhan Başerdem, Anthony Zador, Alexei A. Koulakov, Víctor J. López-Madrona, Ernesto Pereda, Claudio R. Mirasso, Santiago Canals, Stefano Masoli, Udaya B. Rongala, Anton Spanne, Henrik Jorntell, Calogero M. Oddo, Alexander V. Vartanov, Anastasia K. Neklyudova, Stanislav A. Kozlovskiy, Andrey A. Kiselnikov, Julia A. Marakshina, Maria Teleńczuk, Bartosz Teleńczuk, Alain Destexhe, Paula T. Kuokkanen, Anna Kraemer, Thomas McColgan, Catherine E. Carr, Richard Kempter

Publikováno v: BMC Neuroscience, Vol 18, Iss S1, Pp 1-82 (2017)

Externí odkaz: https://doaj.org/article/7aa2e239a0cc44ce9e290243885c7890

Beta bursting in the retrosplenial cortex is a neurophysiological correlate of environmental novelty which is disrupted in a mouse model of Alzheimer’s disease

Autor: Andrew D. Randall, Maria Garcia Garrido, Jonathan Witton, Callum Walsh, Jonathan T. Brown, Thomas Ridler

The retrosplenial cortex (RSC) plays a significant role in spatial learning and memory, and is functionally disrupted in the early stages of Alzheimer’s disease. In order to investigate neurophysiological correlates of spatial learning and memory i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e763d4ac211251870ad662486d474400
https://doi.org/10.1101/2021.04.26.441462

Impaired speed encoding and grid cell periodicity in a mouse model of tauopathy

Autor: Jonathan T. Brown, Thomas Ridler, Andrew D. Randall, Jonathan Witton, Keith G. Phillips

Publikováno v: eLife
eLife, Vol 9 (2020)

Dementia is associated with severe spatial memory deficits which arise from dysfunction in hippocampal and parahippocampal circuits. For spatially sensitive neurons, such as grid cells, to faithfully represent the environment these circuits require p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d19f485c1eacf8dcb6ee419ca8e1909
https://pubmed.ncbi.nlm.nih.gov/33242304