Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Thomas Ratajczak"'
Autor:
Melanie A. Sultana, Carmel Cluning, Wai-Sin Kwong, Nicole Polain, Nathan J. Pavlos, Thomas Ratajczak, John P. Walsh, Jiake Xu, Sarah L. Rea
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
The LIM-domain containing protein Ajuba and the scaffold protein SQSTM1/p62 regulate signalling of NF-κB, a transcription factor involved in osteoclast differentiation and survival. The ubiquitin-associated domain of SQSTM1/p62 is frequently mutated
Externí odkaz:
https://doaj.org/article/ce95db131b1e48aea8e11c033670fb12
Autor:
Thomas Ratajczak
Publikováno v:
GesundheitsRecht. 21:474-475
Autor:
Nicole Polain, Wai Sin Kwong, Thomas Ratajczak, Sarah L. Rea, John P. Walsh, Carmel Cluning, Melanie A. Sultana, Jiake Xu, Nathan J. Pavlos
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259556 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259556 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
The LIM-domain containing protein Ajuba and the scaffold protein SQSTM1/p62 regulate signalling of NF-κB, a transcription factor involved in osteoclast differentiation and survival. The ubiquitin-associated domain of SQSTM1/p62 is frequently mutated
Autor:
Thomas Ratajczak
Publikováno v:
Der Freie Zahnarzt. 61:20-22
Als die Praxisbegehungen begannen, stellten sich ob des meist vorgefundenen Zustandes wenige Fragen nach der Rechtmasigkeit oder Verhaltnismasigkeit der angeordneten Masnahmen. Das schlagt sich in den veroffentlichten Entscheidungen nieder. Das Verwa
Autor:
Thomas Ratajczak
Publikováno v:
Current Molecular Pharmacology. 9:66-95
The steroid receptor-associated TPR cochaperones FKBP51, FKBP52, CyP40 and PP5 have non-redundant roles in steroid receptor function that impact steroid hormone-binding affinity, nucleocyoplasmic shuttling and transcriptional activation of target gen
Autor:
Jennifer Tickner, Haotian Feng, Taksum Cheng, Thomas Ratajczak, Nathan J. Pavlos, Huazi Xu, Sipin Zhu, John P. Walsh, Jiake Xu, Sarah L. Rea
Publikováno v:
Journal of Cellular Biochemistry. 117:1464-1470
Vacuolar proton pump H(+)-adenosine triphosphatases (V-ATPases) play an important role in osteoclast function. Further understanding of the cellular and molecular mechanisms of V-ATPase inhibition is vital for the development of anti-resorptive drugs
Publikováno v:
Calcified tissue international. 101(6)
Studies from several countries suggest that the incidence of Paget’s disease of bone (PDB) and the severity of newly diagnosed cases are declining. The aim of this study was to examine secular changes in clinical presentation of PDB in Australia, w
Autor:
Francesca Giusti, Teresa Esposito, Daniela Merlotti, Micaela Rios Visconti, Stuart H. Ralston, Nerea Alonso, Luigi Gennari, Fernando Gianfrancesco, Marco Di Stefano, L.C. Ward, Giancarlo Isaia, Rogelio González-Sarmiento, John P. Walsh, Omar M. E. Albagha, Maria Luisa Brandi, Sachin Wani, Thomas Ratajczak, William D. Fraser, Luis Corral-Gudino, Javier del Pino-Montes, Domenico Rendina, Kirsteen Goodman, Sarah L. Rea
Publikováno v:
Journal of Bone and Mineral Research. 28:2338-2346
Paget's disease of bone (PDB) has a strong genetic component. Here, we investigated possible associations between genetic variants that predispose to PDB and disease severity. Allelic variants identified as predictors of PDB from genome-wide associat
Autor:
Ajanthy Arulpragasam, Bryan K. Ward, Thomas Ratajczak, Sarah L. Rea, Peter J. Fuller, Carmel Cluning
Publikováno v:
Molecular Endocrinology. 27:1020-1035
The heat-shock protein 90 (Hsp90) cochaperone FK506-binding protein 52 (FKBP52) upregulates, whereas FKBP51 inhibits, hormone binding and nuclear targeting of the glucocorticoid receptor (GR). Decreased cortisol sensitivity in the guinea pig is attri
Autor:
Sarah L. Rea, B. Kevin Park, Christopher E. Goldring, Jed Long, Mark S. Searle, Andrew J. Bennett, Alice Goode, Thomas Ratajczak, Tao Wright, Ian M. Copple, Robert Layfield
Publikováno v:
Bone. 52:699-706
Mutations affecting the Sequestosome 1 (SQSTM1) gene commonly occur in patients with the skeletal disorder Paget's disease of bone (PDB), a condition characterised by defective osteoclast differentiation and function. Whilst most mutations cluster wi