Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Thomas R. Tice"'
Publikováno v:
Nature Reviews Materials. 7:406-420
Autor:
S. Esmail Tabibi, Thomas R. Tice
Publikováno v:
Treatise on Controlled Drug Delivery ISBN: 9780203735022
This chapter highlights some of the key factors in designing and developing parenteral controlled-release dosage forms. It addresses some of the reasons why one would select a parenteral controlled-release dosage form over other controlled-release do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d41d5f43ec978f552d8530e9f6444d
https://doi.org/10.1201/9780203735022-7
https://doi.org/10.1201/9780203735022-7
Autor:
Martin A. Cheever, Sally Mossman, Kenneth H. Grabstein, H. Fang, Lawrence Evans, Mark E. Johnson, Syamal Raychaudhuri, Thomas R. Tice, Jay K. Staas
Publikováno v:
Vaccine. 23:3545-3554
With the ultimate goal of developing a therapeutic cancer vaccine, we encapsulated the Her-2/neu peptide p369-377 in poly(lactide-co-glycolide) microspheres. This formulation was found to effectively elicit CD8+ cytotoxic T cell (CTL) responses in an
Publikováno v:
Molecular and Chemical Neuropathology. 16:123-141
Injectable local drug delivery formulations—so-called microspheres —have recently been developed, in which drugs are microencapsulated within biocompatible and biodegradable copolymer excipients like poly[DL-lactide-co-glycolide]. In view of its
Autor:
Jay K. Staas, J A Meulbroek, Thomas R. Tice, Richard M. Gilley, Jerry R. McGhee, John H. Eldridge
Publikováno v:
Molecular Immunology. 28:287-294
The utility of biodegradable and biocompatible microspheres as a vaccine delivery system for the induction of systemic and disseminated mucosal antibody responses was investigated. Intraperitoneal (ip) injection into mice of 1-10 microns microspheres
Publikováno v:
Journal of Neural Transplantation & Plasticity
Biodegradable controlled-release microsphere systems made with the biocompatible biodegradable polyester excipient poly [DL lactide-co-glycolide] constitute an exciting new technology for drug delivery to the central nervous system (CNS). The present
Autor:
Richard M. Gilley, Michael E. Hudson, Thomas R. Tice, Maninder S. Hora, Rajsharan K. Rana, Jack H. Nunberg
Publikováno v:
Pharmaceutical Research. :1190-1194
Human serum albumin (HSA) was encapsulated in a 50:50 copolymer of DL-lactide/glycolide in the form of microspheres. These microspheres were used as a model formulation to study the feasibility of controlling the release of large proteins over a 20-
Autor:
J A Meulbroek, Thomas R. Tice, Charlotte J. Hammond, Jay K. Staas, Richard M. Gilley, John H. Eldridge
Publikováno v:
Journal of Controlled Release. 11:205-214
Microspheres prepared from various polymers were evaluated for their usefulness as carriers for the targeted delivery of vaccine antigens to the gut-associated lymphoid tissues. Following oral administration to mice, microspheres consisting of polyst
Autor:
Carey McInnis, David W. Mason, William W. Snow, Thomas R. Tice, Darryl F. Love, Jay K. Staas, Anthony P. Nicholas, Kiran Gupta, Teresa M. Ferrell
Publikováno v:
Neuroscience letters. 323(2)
Biodegradable microspheres made with poly-[D,L-lactide-co-glycolide] represent an evolving technology for drug delivery into the central nervous system. Even though these microspheres have been shown to be engulfed by astrocytes in vitro, the purpose
Autor:
Annica B. Dahlstrom, Thomas R. Tice, Stephan Hjorth, Eng-Ang Ling, Amanda McRae, David W. Mason
Publikováno v:
Alzheimer’s and Parkinson’s Diseases ISBN: 9781475791471
The main neurochemical characteristic of Parkinson’s disease (PD) is a marked lesion of the nigro-striatal dopamine pathway. In attempts to provide dopamine replacement therapy to Parkinson’s patients, the current medication is L-DOPA (Birkmayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e5d767798b6069754a1df40a3e7a73
https://doi.org/10.1007/978-1-4757-9145-7_62
https://doi.org/10.1007/978-1-4757-9145-7_62