Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Thomas R. Sattelberg"'
Autor:
John K. Thottathil and, and Sandra L. Quinlan, Derron R. Stark, Brodfuehrer Paul R, Bang-Chi Chen, J. Gregory Reid, Smith Patrick R, Jayachandra P. Reddy, Shaopeng Wang, Thomas R. Sattelberg
Publikováno v:
The Journal of Organic Chemistry. 62:9192-9202
An efficient synthesis of the antimigraine drug candidate avitriptan (1, BMS 180048) is reported. The key step is a two-phase Fischer indolization reaction between hydrazine 6 and 5-chlorovaleraldehyde, 20, to give the chloropropylindole 35, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0e2d61ff090f280d3b9806a54748a6
https://doi.org/10.1021/jo971368q
https://doi.org/10.1021/jo971368q
Autor:
Wayne A. Spitzer, Thomas R. Sattelberg, Chris C. Lee, Emma R. McKinney, Shawn Christopher Miller, Mark Joseph Tebbe, Frantz Victor, J. Tang
Publikováno v:
Journal of Medicinal Chemistry. 40:3937-3946
In an effort to find an orally bioavailable antiviral for the treatment of rhino/enteroviral infections, a series of vinylacetylene benzimidazoles (11a-o, 12, and 18a) was made. Initial studies of this class of antivirals showed that fluorine substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37349dd8293e568e5c5f37ad1e741394
https://doi.org/10.1021/jm970423k
https://doi.org/10.1021/jm970423k