Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Thomas R. Mumford"'
Autor:
David Gonzalez-Martinez, Lee Roth, Thomas R. Mumford, Juan Guan, Anh Le, Robert C. Doebele, Bo Huang, Asmin Tulpule, Magdalena Niewiadomska-Bugaj, Trever G. Bivona, Lukasz J. Bugaj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Drug resistance remains a challenge for targeted therapy of cancers driven by EML4-ALK and related fusion oncogenes. EML4-ALK forms cytoplasmic protein condensates, which result from networks of interactions between oncogene and adapter prot
Externí odkaz:
https://doaj.org/article/369d4a9ed829495a9689692c1e1918f3
Optogenetic clustering is a versatile method to control protein activity in living cells, tissues, and organisms. Here we show that the BcLOV4 photoreceptor both clusters and translocates to the plasma membrane in response to blue light, representing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c6968065bdf00bc9cb0f67b2d85441c
https://doi.org/10.1101/2022.12.12.520131
https://doi.org/10.1101/2022.12.12.520131
Autor:
Thomas R. Mumford, Diarmid Rae, Abbas Idris, David Gonzalez-Martinez, Ayush Aditya Pal, Lukasz J. Bugaj
Protein clustering plays numerous roles in cell physiology and disease. However, protein oligomers can be difficult to detect because they are often small and fall below the detection limits of conventional fluorescence microscopy. Existing technique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::382bd95fd15527a4aee4691e9a6d4fed
https://doi.org/10.1101/2022.07.13.499962
https://doi.org/10.1101/2022.07.13.499962
Publikováno v:
Curr Opin Biomed Eng
Understanding how cells self-organize into functional higher-order structures is of great interest, both towards deciphering animal development, as well as for our ability to predictably build custom tissues to meet research and therapeutic needs. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d048ec7ebc28fad74d1bf87bbc45dc4
https://pubmed.ncbi.nlm.nih.gov/33718689
https://pubmed.ncbi.nlm.nih.gov/33718689
Autor:
Brian Cousens, Thomas R. Mumford
Publikováno v:
Canadian Journal of Earth Sciences. 51:419-438
Paleoproterozoic magmatism in the southern Slave region records the tectonic breakup of Scalvia and the formation of Nuna/Columbia. Constraints on Paleoproterozoic intrusions, therefore, have a direct influence on tectonic reconstructions of this per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c8d7b18f8e4db3a33283c868fede91
https://doi.org/10.1139/cjes-2013-0124
https://doi.org/10.1139/cjes-2013-0124