Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thomas R. Kirkman"'
Publikováno v:
Annals of Vascular Surgery. 31:179-185
Background Intimal hyperplasia at the venous anastomosis of dialysis grafts causes early failure. We developed a sheep model of arteriovenous prosthetic grafts that fail rapidly due to intimal hyperplasia with histologic features nearly identical to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9858ce1d5acee962148152cd37610c60
https://doi.org/10.1016/j.avsg.2015.10.008
https://doi.org/10.1016/j.avsg.2015.10.008
Autor:
Ted R. Kohler, Thomas R. Kirkman
Publikováno v:
Journal of Vascular Surgery. 30:744-751
Purpose: Intimal hyperplasia at the venous anastomosis of dialysis access grafts causes early failure, although increased flow inhibits intimal hyperplasia in arterial grafts and after vessel injury. We designed a sheep model to study this process. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6b070de221ab315f97a9118d8d755b
https://doi.org/10.1016/s0741-5214(99)70114-x
https://doi.org/10.1016/s0741-5214(99)70114-x
Autor:
Larry W. Kraiss, Thomas B. Barrett, Alexander W. Clowes, Charles E. Hart, Russell Ross, Daniel F. Bowen-Pope, Ronald A. Seifert, Josiah N. Wilcox, Elaine W. Raines, Thomas R. Kirkman
Publikováno v:
Journal of Clinical Investigation. 92:338-348
Healing baboon polytetrafluoroethylene grafts express PDGF mRNA in the neointima. Perfusates of graft segments also contain PDGF-like mitogenic activity. To extend these findings, we studied the expression and regional distribution of the PDGF protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8728f7fe1f52372d8e0261f1f637a926
https://doi.org/10.1172/jci116572
https://doi.org/10.1172/jci116572
Autor:
Larry A. Bauer, Larry W. Kraiss, Ted R. Kohler, Thomas R. Kirkman, William G. Reiss, John R. Horn, Brenda K. Zierler, Alexander W. Clowes
Publikováno v:
Journal of Vascular Surgery. 16:0520-0526
This study examined the accuracy of duplex ultrasound measurements of volume flow in a baboon model. Volume flow (V f ) through the external iliac artery was calculated from measurements of blood velocity averaged over several cardiac cycles (time-av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14483c3dad39c6f3aac7a7fed5adc23e
https://doi.org/10.1067/mva.1992.39416
https://doi.org/10.1067/mva.1992.39416
Autor:
Michael A. Golden, Thomas R. Kirkman, Alexander W. Clowes, Josiah N. Wilcox, Russell Ross, Y P Au, Elaine W. Raines
Publikováno v:
Journal of Clinical Investigation. 87:406-414
In a baboon graft model of arterial intimal thickening, smooth muscle cells (SMC) have been observed to proliferate underneath an intact monolayer of endothelium and in the absence of platelet adherence. Because platelets are not present and therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6c4d505fab3683b516ccc3d33fff3c
https://doi.org/10.1172/jci115011
https://doi.org/10.1172/jci115011
Publikováno v:
Journal of Vascular Surgery. 11:838-845
The importance of porosity in synthetic arterial graft healing has not been adequately defined. To determine the effect of porosity on graft healing, we measured the extent of cellular response at late times in 4 mm internal diameter polytetrafluoroe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6344cc0429e3eb2e4c24a7011925bd3c
https://doi.org/10.1016/0741-5214(90)90082-l
https://doi.org/10.1016/0741-5214(90)90082-l
Autor:
Larry W. Kraiss, Richard D. Kenagy, Thomas R. Kirkman, Selina Vergel, Simon Tickle, Debra G. Gilbertson, Helene Finney, Alexander W. Clowes, Geoff Yarranton, Charles E. Hart, David L. Crandall
Publikováno v:
Circulation. 99(4)
Background —We have evaluated the use of a mouse/human chimeric anti–platelet-derived growth factor-β receptor antibody in combination with heparin to inhibit intimal hyperplasia in the saphenous artery of the baboon after balloon angioplasty. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac48260ca5726c9367957b65768f019
https://pubmed.ncbi.nlm.nih.gov/9927405
https://pubmed.ncbi.nlm.nih.gov/9927405
Autor:
Thomas R. Kirkman, Ted R. Kohler
Publikováno v:
Journal of vascular surgery. 28(1)
Purpose: Thrombosis associated with central venous catheters is a significant cause of device failure, morbidity, and loss of access sites. We hypothesized that central vein thrombosis is caused by catheter injury to the vein wall and that it can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ef304f4ac9d6a51bc77e6612522eff
https://pubmed.ncbi.nlm.nih.gov/9685131
https://pubmed.ncbi.nlm.nih.gov/9685131
Publikováno v:
Circulation research. 74(1)
Polytetrafluoroethylene (PTFE) grafts placed into the arterial circulation of baboons for 8 weeks under high blood flow (HF) conditions develop a thin intima composed of smooth muscle cells (SMCs) and extracellular matrix beneath an endothelial monol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3592372a861ce419d5f6857e2b2546f6
https://pubmed.ncbi.nlm.nih.gov/8261588
https://pubmed.ncbi.nlm.nih.gov/8261588
Publikováno v:
Arteriosclerosis and thrombosis : a journal of vascular biology. 11(6)
High shear stress appears to decrease wall thickening in diseased arteries and vascular grafts. To determine if increased shear stress diminishes smooth muscle (SMC) proliferation, we studied the effect of increased blood flow on neointimal thickenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517a29e24863578151d64b1902df8d30
https://pubmed.ncbi.nlm.nih.gov/1931886
https://pubmed.ncbi.nlm.nih.gov/1931886