Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Thomas R. Jackson"'
Autor:
Thomas R. Jackson, Aini Vuorinen, Laia Josa-Culleré, Katrina S. Madden, Daniel Conole, Thomas J. Cogswell, Isabel V.L. Wilkinson, Laura M. Kettyle, Douzi Zhang, Alison O’Mahony, Deanne Gracias, Lorna McCall, Robert Westwood, Georg C. Terstappen, Stephen G. Davies, Edward W. Tate, Graham M. Wynne, Paresh Vyas, Angela J. Russell, Thomas A. Milne
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104787- (2022)
Summary: Despite much progress in developing better drugs, many patients with acute myeloid leukemia (AML) still die within a year of diagnosis. This is partly because it is difficult to identify therapeutic targets that are effective across multiple
Externí odkaz:
https://doaj.org/article/41383f2f5a8d4ffeb2940ad8bb573d15
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Human B-lymphopoiesis is a dynamic life-long process that starts in utero by around six post-conception weeks. A detailed understanding of human fetal B-lymphopoiesis and how it changes in postnatal life is vital for building a complete picture of no
Externí odkaz:
https://doaj.org/article/58023e89fc8f4693b9c552771cceb826
Autor:
Laia Josa-Culleré, Thomas J. Cogswell, Irene Georgiou, Morgan Jay-Smith, Thomas R. Jackson, Carole J. R. Bataille, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
Publikováno v:
Molecules, Vol 26, Iss 21, p 6648 (2021)
Acute myeloid leukemia (AML) is the most aggressive type of blood cancer, and there is a continued need for new treatments that are well tolerated and improve long-term survival rates in patients. Induction of differentiation has emerged as a promisi
Externí odkaz:
https://doaj.org/article/371c3b38b9e44be49d8dc114324e28ce
Autor:
Thomas A. Milne, Graham Trevitt, Stephen G. Davies, Douzi Zhang, Thomas R. Jackson, Angela J. Russell, Katrina S. Madden, Laia Josa-Culleré, Paresh Vyas, Graham Michael Wynne, Tom S. Carter, Thomas J. Cogswell
Publikováno v:
Journal of Medicinal Chemistry. 64:15608-15628
Induction of differentiation is a promising therapeutic strategy against acute myeloid leukemia. However, current differentiation therapies are effective only to specific patient populations. To identify novel differentiation agents with wider effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203e8ec83667a61e34f8c6a1755a1032
https://doi.org/10.1021/acs.jmedchem.1c00574
https://doi.org/10.1021/acs.jmedchem.1c00574
Autor:
Laia Josa-Culleré, Sébastien R.G. Galan, Thomas J. Cogswell, Thomas R. Jackson, Morgan Jay-Smith, Laura Mola, Christopher R. Greaves, Tom S. Carter, Katrina S. Madden, Sophie Trott, Douzi Zhang, Carole J.R. Bataille, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Alan Naylor, Graham M. Wynne, Angela J. Russell
Publikováno v:
European Journal of Medicinal Chemistry. :115509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a62f3e71596eecfc453f94d9f831f19
https://doi.org/10.1016/j.ejmech.2023.115509
https://doi.org/10.1016/j.ejmech.2023.115509
Autor:
Thomas R. Jackson, Graham Michael Wynne, Thomas J. Cogswell, Laia Josa-Culleré, Morgan Jay-Smith, Angela J. Russell, Carole J. R. Bataille, Irene Georgiou, Paresh Vyas, Stephen G. Davies, Thomas A. Milne
Publikováno v:
Molecules; Volume 26; Issue 21; Pages: 6648
Molecules, Vol 26, Iss 6648, p 6648 (2021)
Molecules
Molecules, Vol 26, Iss 6648, p 6648 (2021)
Molecules
Acute myeloid leukemia (AML) is the most aggressive type of blood cancer, and there is a continued need for new treatments that are well tolerated and improve long-term survival rates in patients. Induction of differentiation has emerged as a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb4dfc773c16b54e736ef93ffcf4e6a
https://doi.org/10.3390/molecules26216648
https://doi.org/10.3390/molecules26216648
Autor:
Laia, Josa-Culleré, Katrina S, Madden, Thomas J, Cogswell, Thomas R, Jackson, Tom S, Carter, Douzi, Zhang, Graham, Trevitt, Stephen G, Davies, Paresh, Vyas, Graham M, Wynne, Thomas A, Milne, Angela J, Russell
Publikováno v:
Journal of medicinal chemistry. 64(21)
Induction of differentiation is a promising therapeutic strategy against acute myeloid leukemia. However, current differentiation therapies are effective only to specific patient populations. To identify novel differentiation agents with wider effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f456db9dfc9c87d6ea7537a66363df32
https://pubmed.ncbi.nlm.nih.gov/34672555
https://pubmed.ncbi.nlm.nih.gov/34672555
Autor:
A Vuorinen, Stephen G. Davies, Thomas R. Jackson, Edward W. Tate, O’Mahony A, Gracias D, Daniel Conole, Douzi Zhang, Katrina S. Madden, Thomas J. Cogswell, Wilkinson Ivl., Robert Westwood, Graham Michael Wynne, Laia Josa-Culleré, Andrew Russell, Kettyle Lm, McCall L, Terstappen Gc, Paresh Vyas, Thomas A. Milne
Acute Myeloid Leukaemia (AML) continues to have a poor prognosis, especially in the elderly. One reason for this is that many treatment regimens are not well tolerated by elderly patients. Much current focus is on the development of therapies that ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d1fed02635c076e4bc29741abfc5df
https://doi.org/10.1101/2021.06.03.446952
https://doi.org/10.1101/2021.06.03.446952
Autor:
Thomas R. Jackson, Tom S. Carter, Thomas J. Cogswell, Thomas A. Milne, Katrina S. Madden, Angela J. Russell, Laia Josa-Culleré, Douzi Zhang, Stephen G. Davies, Graham Trevitt, Graham Michael Wynne, Paresh Vyas
Induction of differentiation is a promising therapeutic strategy against acute myeloid leukemia. However, current differentiation therapies are effective only to specific patient populations. To identify novel differentiation agents with wider effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef5cfcdeb5f3855fb1c3cb6e2dc3b6ef
https://doi.org/10.1101/2020.12.18.423389
https://doi.org/10.1101/2020.12.18.423389
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Human B-lymphopoiesis is a dynamic life-long process that startsin uteroby around six post-conception weeks. A detailed understanding of human fetal B-lymphopoiesis and how it changes in postnatal life is vital for building a complete picture of norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb151149c99514f222df952ec324932
https://pubmed.ncbi.nlm.nih.gov/33679795
https://pubmed.ncbi.nlm.nih.gov/33679795