Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Thomas R. Beattie"'
Autor:
Jiangyu Yan, Thomas R. Beattie, Adriana L. Rojas, Kelly Schermerhorn, Tamzin Gristwood, Jonathan C. Trinidad, Sonja V. Albers, Pietro Roversi, Andrew F. Gardner, Nicola G. A. Abrescia, Stephen D. Bell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The current model for B-family DNA polymerases in archaea is one of single-subunit enzymes in contrast to the multi-subunit complexes in eukaryotes. Here the authors show that PolB1 fromSulfolobus solfataricusexists as a heterotrimeric complex in cel
Externí odkaz:
https://doaj.org/article/627c7d9ffa8c4d6aa1b8ab4ad90d0baa
Autor:
Thomas R Beattie, Nitin Kapadia, Emilien Nicolas, Stephan Uphoff, Adam JM Wollman, Mark C Leake, Rodrigo Reyes-Lamothe
Publikováno v:
eLife, Vol 6 (2017)
The replisome is a multiprotein machine that carries out DNA replication. In Escherichia coli, a single pair of replisomes is responsible for duplicating the entire 4.6 Mbp circular chromosome. In vitro studies of reconstituted E. coli replisomes hav
Externí odkaz:
https://doaj.org/article/8c4da7c5d9c146bbb1eeaeb0b9daa265
Autor:
Ziad W El-Hajj, Angela J. Yu, Rodrigo Reyes-Lamothe, Thomas R. Beattie, Nitin Kapadia, Huan Zheng
Publikováno v:
Molecular cell. 80(1)
Summary DNA replication is carried out by a multi-protein machine called the replisome. In Saccharomyces cerevisiae, the replisome is composed of over 30 different proteins arranged into multiple subassemblies, each performing distinct activities. Sy
Autor:
Angela J. Yu, Nitin Kapadia, Thomas R. Beattie, Huan Zheng, Rodrigo Reyes Lamothe, Ziad W El-Hajj
DNA replication is carried out by a multi-protein machine called the replisome. InSaccharomyces cerevisiae, the replisome is composed of over 30 different proteins arranged into multiple subassemblies, each performing distinct activities. Synchrony o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79be11476b799c78f875f132204a3da
https://doi.org/10.1101/780270
https://doi.org/10.1101/780270
Autor:
Mark C. Leake, Emilien Nicolas, Thomas R. Beattie, Adam J. M. Wollman, Rodrigo Reyes-Lamothe, Stephan Uphoff, Nitin Kapadia
Publikováno v:
eLife, Vol 6 (2017)
eLife, 6
eLife
eLife, 6
eLife
The replisome is a multiprotein machine that carries out DNA replication. In Escherichia coli, a single pair of replisomes is responsible for duplicating the entire 4.6 Mbp circular chromosome. In vitro studies of reconstituted E. coli replisomes hav
Autor:
Sonja-Verena Albers, Kelly M. Schermerhorn, Thomas R. Beattie, Pietro Roversi, Jiangyu Yan, Jonathan C. Trinidad, Adriana L. Rojas, Andrew F. Gardner, Stephen D. Bell, Nicola G. A. Abrescia, Tamzin Gristwood
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
'Nature Communications ', vol: 8, pages: 15075-1-15075-15 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
'Nature Communications ', vol: 8, pages: 15075-1-15075-15 (2017)
Since their initial characterization over 30 years ago, it has been believed that the archaeal B-family DNA polymerases are single-subunit enzymes. This contrasts with the multi-subunit B-family replicative polymerases of eukaryotes. Here we reveal t
Autor:
Stephen D. Bell, Thomas R. Beattie
Efficient processing of Okazaki fragments generated during discontinuous lagging-strand DNA replication is critical for the maintenance of genome integrity. In eukaryotes, a number of enzymes co-ordinate to ensure the removal of initiating primers fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3760c6c83fc81b0482be2b9486ed593c
https://doi.org/10.1042/bst0390070
https://doi.org/10.1042/bst0390070
Autor:
Thomas R. Beattie, Stephen D. Bell
Publikováno v:
The EMBO Journal. 31:1556-1567
Chromosomal DNA replication requires one daughter strand—the lagging strand—to be synthesised as a series of discontinuous, RNA-primed Okazaki fragments, which must subsequently be matured into a single covalent DNA strand. Here, we describe the
Autor:
Thomas R. Beattie
Publikováno v:
C&EN Global Enterprise. 96:31-31
Immediately after the conclusion of the ACS Council meeting at the ACS national meeting in Boston in August, the Senior Chemists Committee convened a facilitated strategic planning retreat follow-up meeting. Fifteen current members and associates, as