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pro vyhledávání: '"Thomas R. Beam"'
Autor:
Thomas R. Beam
Publikováno v:
Critical Care Nursing Clinics of North America. 6:275-293
Anti-infective drugs may be used to prevent or treat infectious diseases. Preventing serious infections using aerosolized drugs, selective decontamination of the intestinal tract, or devices impregnated with anti-infective materials generally has bee
Publikováno v:
Journal of Antimicrobial Chemotherapy. 33:1060-1064
Publikováno v:
Clinical Infectious Diseases. 15:S5-S32
This document provides new general guidelines for the design and execution of studies evaluating anti-infective drugs for the prevention or treatment of infectious diseases. The first step in evaluation is the determination of in vitro microbial susc
Publikováno v:
Clinical Infectious Diseases. 14:S246-S251
The evaluation of antibacterial therapy for urinary tract infection (UTI) is based on the results of randomized, controlled comparative studies (preferably double-blinded) in which sufficient numbers of patients are entered into both arms to ensure s
Publikováno v:
Clinical Infectious Diseases. 13:S890-S894
This article describes the current collaborative effort of the U.S. Food and Drug Administration and the Infectious Diseases Society of America to generate new general and disease/organism-specific guidelines for the evaluation of anti-infective agen
Publikováno v:
Antimicrobic Newsletter. 7:1-4
The 1977 Guidelines for the Evaluation of Anti-infective Drug Products are no longer useful. The IDSA has established a contract with the FDA to revise and update these documents. Thirteen sub-committees will address specific areas of infectious dise
Publikováno v:
Drug Information Journal. 24:225-229
For the past decade, one of the most active areas in drug development has been the introduction of new anti- infective drug products. Determination of safety and efficacy by the Food and Drug Administration are guided by the General Considerations fo
Publikováno v:
Diagnostic microbiology and infectious disease. 17(1)
The in vitro activity of sparfloxacin was compared with the activities of ciprofloxacin, ofloxacin, and six other antimicrobial agents against 323 bloodstream isolates of staphylococci (both oxacillin susceptible and resistant) enterococci, and pneum
Autor:
Coleman Rotstein, Theresa Lawrence, Daniel Amsterdam, Thomas R. Beam, Lionel A. Mandell, E A Gorzynski
Publikováno v:
The Journal of antimicrobial chemotherapy. 28
Temafloxacin, a new fluoroquinolone with enhanced activity against Gram-positive bacteria, was compared with other antibiotics. A review of the literature on the in-vitro activity of temafloxacin was also done. The susceptibility of Gram-positive coc