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pro vyhledávání: '"Thomas R. Alosco"'
Autor:
H. L. Bumpers, Nicholas J. Petrelli, Eddie L. Hoover, Hui-Qun Wang, Thomas R. Alosco, Richard B. Bankert
Publikováno v:
Journal of Clinical Investigation. 94:2153-2157
Human villous adenomas are thought to represent premalignancies that subsequently give rise to colorectal adenocarcinomas. Currently there is no in vivo model in which to study the dedifferentiation and malignant transformation of these tumors. We es
Publikováno v:
Cell Adhesion and Communication. 2:345-357
Previously we reported that over 75% of human non-small cell lung cancers overexpress the beta 1 integrin VLA-2 on their surface and show an increase in the mRNA encoding the alpha-2 chain of this integrin. These results suggested the possibility tha
Publikováno v:
Cancer Immunology Immunotherapy. 36:364-372
Transfection of tumor cells with a vector containing the entire coding sequence of human interleukin-2 (hIL-2) was previously shown to convert the tumorigenic murine fibrosarcoma line CMS-5 into a non-tumorigenic line. The failure of the IL-2-secreti
Autor:
Eddie L. Hoover, Harvey L. Bumpers, Hui Qun Wang, Richard B. Bankert, Thomas R. Alosco, Nicholas J. Petrelli
Publikováno v:
The Journal of surgical research. 61(1)
A major stumbling block in the study of human colorectal cancer metastasis has been the lack of an effective in vivo model producing liver metastasis on a consistent basis. In this study surgical specimens of colorectal carcinoma were implanted in sc
Publikováno v:
Annals of surgical oncology. 1(3)
Background: Lung cancer continues to claim large numbers of human lives each year despite advances made in conventional therapies. The use of biologic response modifiers to modulate the immune system against human tumors is an alternate form of immun