Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Thomas R Tölle"'
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105269 (2014)
BackgroundPostherpetic neuralgia (PHN) is the painful complication of a varicella zoster virus reactivation. We investigated the systemic and local gene expression of pro- and anti-inflammatory cytokine expression in patients with PHN.MethodsThirteen
Externí odkaz:
https://doaj.org/article/a4468f07bcdf492e86a3232bfc43d92a
Autor:
Matti Förster, Friederike Mahn, Ulrich Gockel, Mathias Brosz, Rainer Freynhagen, Thomas R Tölle, Ralf Baron
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68273 (2013)
Axial low back pain can be considered as a syndrome with both nociceptive and neuropathic pain components (mixed-pain). Especially neuropathic pain comprises a therapeutic challenge in practical experience and may explain why pharmacotherapy in back
Externí odkaz:
https://doaj.org/article/107e2c24594943bb9ed4c9ee5a71ec55
Autor:
Andreas Binder, Denisa May, Ralf Baron, Christoph Maier, Thomas R Tölle, Rolf-Detlef Treede, Achim Berthele, Frank Faltraco, Herta Flor, Janne Gierthmühlen, Sierk Haenisch, Volker Huge, Walter Magerl, Christian Maihöfner, Helmut Richter, Roman Rolke, Andrea Scherens, Nurcan Uçeyler, Mike Ufer, Gunnar Wasner, Jihong Zhu, Ingolf Cascorbi
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17387 (2011)
Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropath
Externí odkaz:
https://doaj.org/article/1ab5f65f00504b0c8e7b07b406db7302
Autor:
Friederike Mahn, Philipp Hüllemann, Ulrich Gockel, Mathias Brosz, Rainer Freynhagen, Thomas R Tölle, Ralf Baron
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e18018 (2011)
Painful radiculopathies (RAD) and classical neuropathic pain syndromes (painful diabetic polyneuropathy, postherpetic neuralgia) show differences how the patients express their sensory perceptions. Furthermore, several clinical trials with neuropathi
Externí odkaz:
https://doaj.org/article/40b27f8d4eb4429fa739fb5469bc4608
Autor:
Juliane Sachau, Dilara Kersebaum, Philipp Hüllemann, Daniela Adolf, Maria Kabelitz, Thomas Keller, Rainer Freynhagen, Thomas R. Tölle, Andreas Binder, Ralf Baron
Publikováno v:
PAIN Reports, Vol 8, Iss 5, p e1098 (2023)
Abstract. Introduction:. Patients with neuropathic pain (NP) report a higher impairment of quality of life and sleep than patients with chronic pain without neuropathic characteristics. These include somatosensory peculiarities like allodynia, a surr
Externí odkaz:
https://doaj.org/article/5af61c5e473143c39c83710fe51897a9
Autor:
Walter Zieglgänsberger, Rudolf Brenneisen, Achim Berthele, Carsten T. Wotjak, Borwin Bandelow, Thomas R. Tölle, Beat Lutz
Publikováno v:
Medical Cannabis and Cannabinoids, Vol 5, Iss 1, Pp 61-75 (2022)
The development of a high-end cannabinoid-based therapy is the result of intense translational research, aiming to convert recent discoveries in the laboratory into better treatments for patients. Novel compounds and new regimes for drug treatment ar
Externí odkaz:
https://doaj.org/article/8a6fa50678c7400895b899dbeaf5c1c7
Publikováno v:
MMW - Fortschritte der Medizin. 164:19-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d4dcad9952bb7bf71b3ba313d4dc02
https://doi.org/10.1007/s15006-022-0876-1
https://doi.org/10.1007/s15006-022-0876-1
Publikováno v:
Drugs. 81:2103-2116
Nociplastic pain is defined as pain due to sensitization of the nervous system, without a sufficient underlying anatomical abnormality to explain the severity of pain. Nociplastic pain may be manifest in various organ systems, is often perceived as b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6595fa234fadb7950fe4750f74fac13a
https://doi.org/10.1007/s40265-021-01602-1
https://doi.org/10.1007/s40265-021-01602-1
Autor:
Maija Haanpää, Rolf-Detlef Treede, Rainer Freynhagen, Juliane Sachau, Søren H. Sindrup, Troels S. Jensen, Christoph Maier, Jan Vollert, Janne Gierthmühlen, Jeffrey D. Kennedy, Nadine Attal, Thomas R. Tölle, Didier Bouhassira, Märta Segerdahl, Andrew S.C. Rice, Johann Böhmer, Lise Ventzel, Ralf Baron, Per Hansson
Publikováno v:
Pain
Pain, 2022, 163 (7), pp.1378-1387. ⟨10.1097/j.pain.0000000000002501⟩
Gierthmühlen, J, Böhmer, J, Attal, N, Bouhassira, D, Freynhagen, R, Haanpää, M, Hansson, P, Jensen, T S, Kennedy, J, Maier, C, Rice, A S C, Sachau, J, Segerdahl, M, Sindrup, S, Tölle, T, Treede, R D, Ventzel, L, Vollert, J & Baron, R 2022, ' Association of sensory phenotype with quality of life, functionality, and emotional well-being in patients suffering from neuropathic pain ', Pain, vol. 163, no. 7, pp. 1378-1387 . https://doi.org/10.1097/j.pain.0000000000002501
Pain, 2022, 163 (7), pp.1378-1387. ⟨10.1097/j.pain.0000000000002501⟩
Gierthmühlen, J, Böhmer, J, Attal, N, Bouhassira, D, Freynhagen, R, Haanpää, M, Hansson, P, Jensen, T S, Kennedy, J, Maier, C, Rice, A S C, Sachau, J, Segerdahl, M, Sindrup, S, Tölle, T, Treede, R D, Ventzel, L, Vollert, J & Baron, R 2022, ' Association of sensory phenotype with quality of life, functionality, and emotional well-being in patients suffering from neuropathic pain ', Pain, vol. 163, no. 7, pp. 1378-1387 . https://doi.org/10.1097/j.pain.0000000000002501
International audience; Neuropathic pain highly affects quality of life, well-being, and function. It has recently been shown based on cluster analysis studies that most patients with neuropathic pain may be categorized into 1 of 3 sensory phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be44b1f0c854ed5a4caf55b7739880e1
https://hal.archives-ouvertes.fr/hal-03775747/document
https://hal.archives-ouvertes.fr/hal-03775747/document
Autor:
Thomas R. Tölle, Mary-Ann Fitzcharles, Tino Schubert, Christoph Maier, Tobias Vogelmann, Winfried Häuser
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
BMC Medicine
BMC Medicine
Background Hitherto only studies with selected populations have found an increased all-cause mortality of some selected opioids compared to selected non-opioids for chronic non-cancer pain (CNCP). We have examined the all-cause mortality for CNCP ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a5df1c747bc3d86aebeeda0391b7b1
http://link.springer.com/article/10.1186/s12916-020-01644-4
http://link.springer.com/article/10.1186/s12916-020-01644-4