Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Thomas R Shelite"'
Autor:
Alexandra Cossio, Jimena Jojoa, María Del Mar Castro, Ruth Mabel Castillo, Lyda Osorio, Thomas R Shelite, Nancy Gore Saravia, Peter C Melby, Bruno L Travi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009291 (2021)
BackgroundControl of cutaneous leishmaniasis by public health systems in the Americas relies on case identification and treatment. Point-of-care diagnostics that can be performed by health workers within or near affected communities could effectively
Externí odkaz:
https://doaj.org/article/828e9b7d62c945d4b2c5730e15ee0dc1
Autor:
Brandon Trent, Yuejin Liang, Yan Xing, Marisol Esqueda, Yang Wei, Nam-Hyuk Cho, Hong-Il Kim, Yeon-Sook Kim, Thomas R Shelite, Jiyang Cai, Jiaren Sun, Donald H Bouyer, Jinjun Liu, Lynn Soong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0007675 (2020)
Orientia tsutsugamushi infection can cause acute lung injury and high mortality in humans; however, the underlying mechanisms are unclear. Here, we tested a hypothesis that dysregulated pulmonary inflammation and Tie2-mediated endothelial malfunction
Externí odkaz:
https://doaj.org/article/d3d19fda7f544d5aa5f79320b5c32544
Autor:
Guang Xu, Nicole L Mendell, Yuejin Liang, Thomas R Shelite, Yenny Goez-Rivillas, Lynn Soong, Donald H Bouyer, David H Walker
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006127 (2017)
[This corrects the article DOI: 10.1371/journal.pntd.0005763.].
Externí odkaz:
https://doaj.org/article/a26ed7c3220c4658bfe667e8b7d03f98
Autor:
Lynn Soong, Thomas R Shelite, Yan Xing, Harica Kodakandla, Yuejin Liang, Brandon J Trent, Paulina Horton, Kathryn C Smith, Zhenyang Zhao, Jiaren Sun, Donald H Bouyer, Jiyang Cai
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005765 (2017)
BACKGROUND:Scrub typhus is a life-threatening disease, due to infection with O. tsutsugamushi, a Gram-negative bacterium that preferentially replicates in endothelial cells and professional phagocytes. Meningoencephalitis has been reported in scrub t
Externí odkaz:
https://doaj.org/article/d9461a43e9104496b120af8a6d6e422e
Autor:
Guang Xu, Nicole L Mendell, Yuejin Liang, Thomas R Shelite, Yenny Goez-Rivillas, Lynn Soong, Donald H Bouyer, David H Walker
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005763 (2017)
Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people ar
Externí odkaz:
https://doaj.org/article/3587c79fe0494f2a9f0b6f3b95e12a85
Autor:
Lynn Soong, Nicole L Mendell, Juan P Olano, Dedeke Rockx-Brouwer, Guang Xu, Yenny Goez-Rivillas, Claire Drom, Thomas R Shelite, Gustavo Valbuena, David H Walker, Donald H Bouyer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004884 (2016)
Scrub typhus is a neglected tropical disease, caused by Orientia tsutsugamushi, a Gram-negative bacterium that is transmitted to mammalian hosts during feeding by Leptotrombidium mites and replicates predominantly within endothelial cells. Most studi
Externí odkaz:
https://doaj.org/article/358516a7395e48ddb56afa335825374a
Autor:
Thomas R Shelite, Yuejin Liang, Hui Wang, Nicole L Mendell, Brandon J Trent, Jiaren Sun, Bin Gong, Guang Xu, Haitao Hu, Donald H Bouyer, Lynn Soong
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 3, p e0004467 (2016)
Endothelial cells (EC) are the main target for Orientia tsutsugamushi infection and EC dysfunction is a hallmark of severe scrub typhus in patients. However, the molecular basis of EC dysfunction and its impact on infection outcome are poorly underst
Externí odkaz:
https://doaj.org/article/826f78ab26554b7b82c849b4ded2557f
Autor:
Lynn Soong, Hui Wang, Thomas R Shelite, Yuejin Liang, Nicole L Mendell, Jiaren Sun, Bin Gong, Gustavo A Valbuena, Donald H Bouyer, David H Walker
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3191 (2014)
Scrub typhus is a neglected, but important, tropical disease, which puts one-third of the world's population at risk. The disease is caused by Orientia tsutsugamushi, an obligately intracellular Gram-negative bacterium. Dysregulation in immune respon
Externí odkaz:
https://doaj.org/article/79857d24d93d4a829133c861910a9879
Autor:
Thomas R Shelite, Tais B Saito, Nicole L Mendell, Bin Gong, Guang Xu, Lynn Soong, Gustavo Valbuena, Donald H Bouyer, David H Walker
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2966 (2014)
Orientia tsutsugamushi, the etiologic agent of scrub typhus, is a mite-borne rickettsia transmitted by the parasitic larval stage of trombiculid mites. Approximately one-third of the world's population is at risk of infection with Orientia tsutsugamu
Externí odkaz:
https://doaj.org/article/60dd5a829a284f24a60af78bc4f49988
Autor:
Lijun Xin, Thomas R Shelite, Bin Gong, Nicole L Mendell, Lynn Soong, Rong Fang, David H Walker
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34062 (2012)
Due to its strong immune stimulatory effects through TLR9, CpG-containing oligodeoxynucleotides (CpG ODN) have been tested in multiple clinical trials as vaccine adjuvant for infectious diseases and cancer. However, immune suppression induced by syst
Externí odkaz:
https://doaj.org/article/eeedd412b1634d5ab794cc66d0f426ad