Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Thomas R Hawthorne"'
Autor:
Mario Sznol, Michael Yellin, Tibor Keler, Jose Lutzky, Amy Weise, Margaret K Callahan, Osama Rahma, Rachel E Sanborn, Alexander Starodub, Deepa S Subramaniam, Antonio Jimeno, Tracey Rawls, David A Reardon, Daniel C Cho, Rhonda L Bitting, Michael J Pishvaian, Branimir I Sikic, Naiyer A Rizvi, Julie E Bauman, Thomas Kaley, Fabio Iwamoto, Joachim M Baehring, Jeanny B Aragon-Ching, Thomas R Hawthorne
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background Phase 1/2 dose-escalation and expansion study evaluating varlilumab, a fully human agonist anti-CD27 mAb, with nivolumab in anti-PD-1/L1 naïve, refractory solid tumors.Methods Phase 1 evaluated the safety of varlilumab (0.1–10 mg/kg) wi
Externí odkaz:
https://doaj.org/article/64a076a7b8714d66afa98dfcc1b8a9bc
Autor:
Diego Alvarado, Marcus Maurer, Richard Gedrich, Scott B. Seibel, Michael B. Murphy, Linda Crew, Joel Goldstein, Andrea Crocker, Laura A. Vitale, Pamela A. Morani, Lawrence J. Thomas, Thomas R. Hawthorne, Tibor Keler, Diane Young, Elizabeth Crowley, Martin Kankam, Margo Heath‐Chiozzi
Publikováno v:
Allergy. 77:2393-2403
Mast cells (MC) are powerful inflammatory immune sentinel cells that drive numerous allergic, inflammatory, and pruritic disorders when activated. MC-targeted therapies are approved in several disorders, yet many patients have limited benefit suggest
Autor:
Rachel E Sanborn, Michael J Pishvaian, Margaret K Callahan, Amy Weise, Branimir I Sikic, Osama Rahma, Daniel C Cho, Naiyer A Rizvi, Mario Sznol, Jose Lutzky, Julie E Bauman, Rhonda L Bitting, Alexander Starodub, Antonio Jimeno, David A Reardon, Thomas Kaley, Fabio Iwamoto, Joachim M Baehring, Deepa S Subramaniam, Jeanny B Aragon-Ching, Thomas R Hawthorne, Tracey Rawls, Michael Yellin, Tibor Keler
Publikováno v:
Journal for immunotherapy of cancer. 10(8)
BackgroundPhase 1/2 dose-escalation and expansion study evaluating varlilumab, a fully human agonist anti-CD27 mAb, with nivolumab in anti-PD-1/L1 naïve, refractory solid tumors.MethodsPhase 1 evaluated the safety of varlilumab (0.1–10 mg/kg) with
Autor:
Stephen T. Sonis, Brynmor A. Watkins, William J. Larochelle, Cyrus Karkaria, Gulshan Ara, Thomas R Hawthorne, Haihong Zhong
Publikováno v:
International Journal of Radiation Biology. 84:401-412
Velafermin (recombinant human fibroblast growth factor-20, rhFGF-20) has been shown to reduce the severity and duration of mucositis in preclinical acute (single dose) radiation and chemotherapy/radiation models of oral mucositis. Our present study a
Autor:
Allen H. Neims, Michael J. Ingeno, Thomas R. Hawthorne, John R. T. Vinson, Raymond J. Bergeron, James S. McManis, Rita Bortell
Publikováno v:
Journal of medicinal chemistry. 31(6)
In this paper, we report on the synthesis and biological activity of a number of N-alkylated spermine compounds. The dialkylspermines N1,N12-dimethylspermine (DMSPM-2), N1,N12-diethylspermine (DESPM-3), and N1,N12-dipropylspermine (DPSPM-4) are all s
Publikováno v:
Allergy; Aug2022, Vol. 77 Issue 8, p2277-2283, 7p
Autor:
Alvarado, Diego, Maurer, Marcus, Gedrich, Richard, Seibel, Scott B., Murphy, Michael B., Crew, Linda, Goldstein, Joel, Crocker, Andrea, Vitale, Laura A., Morani, Pamela A., Thomas, Lawrence J., Hawthorne, Thomas R., Keler, Tibor, Young, Diane, Crowley, Elizabeth, Kankam, Martin, Heath‐Chiozzi, Margo
Publikováno v:
Allergy; Aug2022, Vol. 77 Issue 8, p2393-2403, 11p
Autor:
Ara, Gulshan1 (AUTHOR), Watkins, Brynmor A.2 (AUTHOR), Zhong, Haihong1 (AUTHOR), Hawthorne, Thomas R.1 (AUTHOR), Karkaria, Cyrus E.1 (AUTHOR), Sonis, Stephen T.3 (AUTHOR), Larochelle, William J.1 (AUTHOR) wlarochelle@curagen.com
Publikováno v:
International Journal of Radiation Biology. May2008, Vol. 84 Issue 5, p401-412. 12p. 1 Diagram, 1 Chart, 4 Graphs.
Autor:
Smith, Grace E.
Publikováno v:
ATQ. Jun2001, Vol. 15 Issue 2, p149. 13p.
Autor:
WILLIAMS, ZACHARY
Publikováno v:
Nathaniel Hawthorne Review; 2019, Vol. 45 Issue 2, p152-170, 19p