Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Thomas R Fleming"'
Autor:
Robert W Cross, Ira M Longini, Stephan Becker, Karin Bok, David Boucher, Miles W Carroll, Janet V Díaz, William E Dowling, Ruxandra Draghia-Akli, James T Duworko, John M Dye, Michael A Egan, Patricia Fast, Amy Finan, Courtney Finch, Thomas R Fleming, Joan Fusco, Thomas W Geisbert, Anthony Griffiths, Stephan Günther, Lisa E Hensley, Anna Honko, Ruth Hunegnaw, Jocelyn Jakubik, Julie Ledgerwood, Kerstin Luhn, Demetrius Matassov, Jeffrey Meshulam, Emily V Nelson, Christopher L Parks, Roxana Rustomjee, David Safronetz, Lauren M Schwartz, Dean Smith, Paul Smock, Ydrissa Sow, Christina F Spiropoulou, Nancy J Sullivan, Kelly L Warfield, Daniel Wolfe, Courtney Woolsey, Roland Zahn, Ana María Henao-Restrepo, César Muñoz-Fontela, Andrea Marzi
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010805 (2022)
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine "MARVAC" consortium representing leaders in the field of vaccine research and development aiming to facilitate a rapid response to this infectious di
Externí odkaz:
https://doaj.org/article/593ffe829fc54b1d9a21138ad004f3f4
Autor:
Bruce D. Forrest, Namita A. Goyal, Thomas R. Fleming, Paige M. Bracci, Neil R. Brett, Zaeem Khan, Michelle Robinson, Ari Azhir, Michael McGrath
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2367 (2024)
Background/Objectives: The aim of this study was to estimate the effect of a 6 months’ treatment course of the innate immune modulator NP001 (a pH-adjusted intravenous formulation of purified sodium chlorite), on disease progression, as measured by
Externí odkaz:
https://doaj.org/article/d472239dee954f209612297801e36085
Autor:
Ira M Longini, Yang Yang, Thomas R Fleming, César Muñoz-Fontela, Rui Wang, Susan S Ellenberg, George Qian, M Elizabeth Halloran, Martha Nason, Victor De Gruttola, Sabue Mulangu, Yunda Huang, Christl A Donnelly, Ana-Maria Henao Restrepo
Publikováno v:
Clinical Trials. 19:647-654
Background: The threat of a possible Marburg virus disease outbreak in Central and Western Africa is growing. While no Marburg virus vaccines are currently available for use, several candidates are in the pipeline. Building on knowledge and experienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fb4def1039a93dd0bd0d958110c9a1
https://doi.org/10.1177/17407745221110880
https://doi.org/10.1177/17407745221110880
Autor:
Elia M Pestana Knight, Sam Amin, Nadia Bahi-Buisson, Tim A Benke, J Helen Cross, Scott T Demarest, Heather E Olson, Nicola Specchio, Thomas R Fleming, Alex A Aimetti, Maciej Gasior, Orrin Devinsky, Elena Belousova, Oleg Belyaev, Bruria Ben-Zeev, Andreas Brunklaus, Michael A. Ciliberto, Francesca Darra, Ronald Davis, Valentina De Giorgis, Olga Doronina, Michael Fahey, Renzo Guerrini, Peter Heydemann, Olga Khaletskaya, Pawel Lisewski, Eric D. Marsh, Ahsan N. Moosa, Scott Perry, Sunny Philip, Rajsekar R. Rajaraman, Ben Renfroe, Russell P. Saneto, Ingrid E. Scheffer, Yoshimi Sogawa, Bernhardt Suter, Matthew T. Sweney, Daniel Tarquinio, Pierangelo Veggiotti, Geoff Wallace, Judy Weisenberg, Angus Wilfong, Elaine C. Wirrell, Muhammad Zafar, Marta Zolnowska
Publikováno v:
The Lancet Neurology. 21:417-427
CDKL5 deficiency disorder (CDD) is a rare, X-linked, developmental and epileptic encephalopathy characterised by severe global developmental impairment and seizures that can begin in the first few months after birth and are often treatment refractory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22b17fab27a5bde8c7c1a684f969528
https://doi.org/10.1016/s1474-4422(22)00077-1
https://doi.org/10.1016/s1474-4422(22)00077-1
Publikováno v:
The Journal of Infectious Diseases. 226:1863-1866
Decision making about vaccination and boosting schedules for coronavirus disease 2019 (COVID-19) hinges on reliable methods for evaluating the longevity of vaccine protection. We show that modeling of protection as a piecewise linear function of time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35ce0f90b9e94067e7d4f361cba5a8b
https://doi.org/10.1093/infdis/jiac139
https://doi.org/10.1093/infdis/jiac139
Autor:
Narendra K. Arora, Ira M. Longini, J. Peter Figueroa, Michael J. Ryan, Hongchao Pan, Alejandro Cravioto, Julian P T Higgins, Marion Gruber, Ana-Maria Henao-Restrepo, Fatema Kazi, Philip R. Krause, Soumya Swaminathan, Helen Rees, Jonathan A C Sterne, Richard Peto, Thomas R. Fleming, Isabelle Boutron, Rogerio Gaspar
Publikováno v:
Lancet (London, England)
Krause, P R, Fleming, T R, Peto, R, Longini, I M, Figueroa, J P, Sterne, J A C, Cravioto, A, Rees, H, Higgins, J P T, Boutron, I, Pan, H, Gruber, M F, Arora, N, Kazi, F, Gaspar, R, Swaminathan, S, Ryan, M J & Henao-Restrepo, A-M 2021, ' Considerations in boosting COVID-19 vaccine immune responses ', Lancet, vol. 398, no. 10308, pp. 1377-1380 . https://doi.org/10.1016/S0140-6736(21)02046-8
Krause, P R, Fleming, T R, Peto, R, Longini, I M, Figueroa, J P, Sterne, J A C, Cravioto, A, Rees, H, Higgins, J P T, Boutron, I, Pan, H, Gruber, M F, Arora, N, Kazi, F, Gaspar, R, Swaminathan, S, Ryan, M J & Henao-Restrepo, A-M 2021, ' Considerations in boosting COVID-19 vaccine immune responses ', Lancet, vol. 398, no. 10308, pp. 1377-1380 . https://doi.org/10.1016/S0140-6736(21)02046-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e33b0bffd31a142c76eb841cce1229
https://doi.org/10.1016/s0140-6736(21)02046-8
https://doi.org/10.1016/s0140-6736(21)02046-8
Autor:
Brett S Hanscom, Deborah J Donnell, Thomas R Fleming, James P Hughes, Marybeth McCauley, Beatriz Grinsztejn, Raphael J Landovitz, Scott S Emerson
Publikováno v:
Clin Trials
Background/Aims: The HIV Prevention Trials Network 083 trial was a group-sequential non-inferiority trial designed to compare HIV incidence under a novel experimental regimen for HIV prevention, long-acting injectable cabotegravir, with an active-con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2635b744d1e45de9b059a37f02b49fef
https://europepmc.org/articles/PMC9691580/
https://europepmc.org/articles/PMC9691580/
Autor:
Soumya Swaminathan, Marion Gruber, Michael J. Ryan, Philip R. Krause, Valerie Beral, Rogerio Gaspar, Richard Peto, David L Heymann, Alba-Maria Ropero, Jerome Amir Singh, Ran D. Balicer, Maria D. Van Kerkhove, Ana-Maria Henao-Restrepo, Jakob P. Cramer, Ira M. Longini, Sylvie Briand, Thomas R. Fleming, Kanta Subbarao, César Muñoz-Fontela, Matthew D. Snape, Helen Rees
Publikováno v:
The New England Journal of Medicine
Summary Viral variants of concern may emerge with dangerous resistance to the immunity generated by the current vaccines to prevent coronavirus disease 2019 (Covid-19). Moreover, if some variants of concern have increased transmissibility or virulenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b7909bf7717031055f850933c75cdc
https://doi.org/10.1056/nejmsr2105280
https://doi.org/10.1056/nejmsr2105280
Autor:
Jason S. Kim, Silvana Borges, Daniel J. Clauw, Philip G. Conaghan, David T. Felson, Thomas R. Fleming, Rachel Glaser, Elizabeth Hart, Marc Hochberg, Yura Kim, Virginia B. Kraus, Larissa Lapteva, Xiaojuan Li, Sharmila Majumdar, Timothy E. McAlindon, Ali Mobasheri, Tuhina Neogi, Frank W. Roemer, Rebecca Rothwell, Robert Shibuya, Jeffrey Siegel, Lee S. Simon, Kurt P. Spindler, Nikolay P. Nikolov
Publikováno v:
Semin Arthritis Rheum
OBJECTIVE: To summarize proceedings of a workshop convened to discuss the current state of science in the disease of osteoarthritis (OA), identify the knowledge gaps, and examine the developmental and regulatory challenges in bringing these products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f14dcff997bbcc9b5ecfef062e47e7
https://europepmc.org/articles/PMC9452453/
https://europepmc.org/articles/PMC9452453/
Autor:
Thomas R. Fleming, Christine E. Garnett, Laurie S. Conklin, Solange Corriol-Rohou, Sudharshan Hariharan, Daphne Hsu, Guenther Mueller-Velten, Yeruk Mulugeta, Ronald Portman, Mark D. Rothmann, Norman L. Stockbridge, Simon Wandel, Jialu Zhang, Lynne Yao
Publikováno v:
Therapeutic innovationregulatory science. 57(1)
Even with recent substantive improvements in health care in pediatric populations, considerable need remains for additional safe and effective interventions for the prevention and treatment of diseases in children. The approval of prescription drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40989891b158eea2f9b1ca62e1fb45f
https://pubmed.ncbi.nlm.nih.gov/36057747
https://pubmed.ncbi.nlm.nih.gov/36057747