Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Thomas Rülicke"'
Autor:
Laura E Burnett, Peter Koppensteiner, Olga Symonova, Tomás Masson, Tomas Vega-Zuniga, Ximena Contreras, Thomas Rülicke, Ryuichi Shigemoto, Gaia Novarino, Maximilian Joesch
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002668 (2024)
Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals share strikingly similar and correlated behavioural traits that include perceptual and sensory processing challenges. Notably, the severity of these sensory
Externí odkaz:
https://doaj.org/article/86714a1ab5f44238b4ba96712c0317e3
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Maternal investment can affect the survival and development of offspring. Here we experimentally investigated in mice, whether females alter implantation rates and pup survival after embryo transfer depending on the genetic similarity with t
Externí odkaz:
https://doaj.org/article/b8a727823cc64eac9917b2c4bbd40b72
Publikováno v:
Reproduction and Fertility, Vol 4, Iss 2, Pp 1-12 (2023)
In laboratory mice, sperm quality is usually assessed in spermatozoa collected from the cauda epididymidis of freshly sacrificed males. Percutaneous epididymal sperm aspiration (PESA) is a non-terminal alternative that would allow repeated sperm coll
Externí odkaz:
https://doaj.org/article/020a0715b44f4bb48bbcbe5894ce0ac0
Autor:
Gergely Imre, Bertalan Takács, Erik Czipa, Andrea Bakné Drubi, Gábor Jaksa, Dóra Latinovics, Andrea Nagy, Réka Karkas, Liza Hudoba, Bálint Márk Vásárhelyi, Gabriella Pankotai-Bodó, András Blastyák, Zoltán Hegedűs, Péter Germán, Balázs Bálint, Khaldoon Sadiq Ahmed Abdullah, Anna Georgina Kopasz, Anita Kovács, László G. Nagy, Farkas Sükösd, Lajos Pintér, Thomas Rülicke, Endre Barta, István Nagy, Lajos Haracska, Lajos Mátés
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 145-159 (2023)
DNA transposon-based gene delivery vectors represent a promising new branch of randomly integrating vector development for gene therapy. For the side-by-side evaluation of the piggyBac and Sleeping Beauty systems—the only DNA transposons currently
Externí odkaz:
https://doaj.org/article/11d546c2a6444753ab7f307b4cde6bdd
Autor:
Christian F. Guerrero-Juarez, Paul Schilf, Jing Li, Maria Paula Zappia, Lei Bao, Payal M. Patel, Jenny Gieseler-Tillmann, Sripriya Murthy, Connor Cole, Maria Sverdlov, Maxim V. Frolov, Takashi Hashimoto, Norito Ishii, Thomas Rülicke, Katja Bieber, Ralf J. Ludwig, Christian D. Sadik, Kyle T. Amber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInflammatory epidermolysis bullosa acquisita (EBA) is characterized by a neutrophilic response to anti-type VII collagen (COL7) antibodies resulting in the development of skin inflammation and blistering. The antibody transfer model of EB
Externí odkaz:
https://doaj.org/article/1405ecc563cf4c7cb34962308c3e35d5
Autor:
Hui Qian, Xiaojuan Chao, Shaogui Wang, Yuan Li, Xiaoxiao Jiang, Zhaoli Sun, Thomas Rülicke, Kurt Zatloukal, Hong-Min Ni, Wen-Xing Ding
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1027-1049 (2023)
Background: Alcohol-associated liver disease (ALD) is a worldwide health problem, of which the effective treatment is still lacking. Both detrimental and protective roles of adipose tissue have been implicated in ALD. Although alcohol increases adipo
Externí odkaz:
https://doaj.org/article/5da95cf1d2e54448a0f201e209fe9f08
Autor:
Zachary A. Schaaf, Lyvin Tat, Noemi Cannizzaro, Ralph Green, Thomas Rülicke, Simon Hippenmeyer, Konstantinos S. Zarbalis
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Proper cerebral cortical development depends on the tightly orchestrated migration of newly born neurons from the inner ventricular and subventricular zones to the outer cortical plate. Any disturbance in this process during prena
Externí odkaz:
https://doaj.org/article/ec1c5232e330468f88b203349b7c5260
Autor:
Ulrike Schmidt, Betül Uluca, Iva Vokic, Barizah Malik, Thomas Kolbe, Caroline Lassnig, Martin Holcmann, Veronica Moreno-Viedma, Bernhard Robl, Carina Mühlberger, Dagmar Gotthardt, Maria Sibilia, Thomas Rülicke, Mathias Müller, Agnes Csiszar
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0286256 (2023)
FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient survival. Although ILEI's causa
Externí odkaz:
https://doaj.org/article/994b8dfe26b74aa0b5ce6ad114d089ef
Autor:
Hui Qian, Qingyun Bai, Xiao Yang, Jephte Y. Akakpo, Lili Ji, Li Yang, Thomas Rülicke, Kurt Zatloukal, Hartmut Jaeschke, Hong-Min Ni, Wen-Xing Ding
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3791-3805 (2021)
Acetaminophen (APAP) overdose can induce liver injury and is the most frequent cause of acute liver failure in the United States. We investigated the role of p62/SQSTM1 (referred to as p62) in APAP-induced liver injury (AILI) in mice. We found that t
Externí odkaz:
https://doaj.org/article/11c1a25a9fed4671869e8d06a1fde45d
Autor:
Mostafa A. Aboouf, Franco Guscetti, Nadine von Büren, Julia Armbruster, Hyrije Ademi, Maja Ruetten, Florinda Meléndez-Rodríguez, Thomas Rülicke, Alexander Seymer, Robert A. Jacobs, Edith M. Schneider Gasser, Julian Aragones, Drorit Neumann, Max Gassmann, Markus Thiersch
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Erythropoietin receptor (EPOR) is widely expressed in healthy and malignant tissues. In certain malignancies, EPOR stimulates tumor growth. In healthy tissues, EPOR controls processes other than erythropoiesis, including mitochondrial metabolism. We
Externí odkaz:
https://doaj.org/article/310af4056b6044878b44d59abc419570