Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Thomas Rüde"'
Autor:
Marcel Rühling, Louise Kersting, Fabienne Wagner, Fabian Schumacher, Dominik Wigger, Dominic A. Helmerich, Tom Pfeuffer, Robin Elflein, Christian Kappe, Markus Sauer, Christoph Arenz, Burkhard Kleuser, Thomas Rudel, Martin Fraunholz, Jürgen Seibel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Sphingomyelin is a key molecule of sphingolipid metabolism, and its enzymatic breakdown is associated with various infectious diseases. Here, we introduce trifunctional sphingomyelin derivatives that enable the visualization of sphingomyelin
Externí odkaz:
https://doaj.org/article/49744d45d0a244ae925aa7fb11b17b6c
Autor:
Pargev Hovhannisyan, Kathrin Stelzner, Markus Keicher, Kerstin Paprotka, Mastura Neyazi, Mindaugas Pauzuolis, Waled Mohammed Ali, Karthika Rajeeve, Sina Bartfeld, Thomas Rudel
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012144 (2024)
Several reports suggest that intestinal tissue may be a natural niche for Chlamydia trachomatis infection and a reservoir for persistent infections in the human body. Due to the human specificity of the pathogen and the lack of suitable host models,
Externí odkaz:
https://doaj.org/article/551f792c92f8429f9eaaf0b775708c6b
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9977 (2024)
Viruses are obligate intracellular parasites, and they exploit the cellular pathways and resources of their respective host cells to survive and successfully multiply. The strategies of viruses concerning how to take advantage of the metabolic capabi
Externí odkaz:
https://doaj.org/article/935a5b0917204e27a2a44268247d31bd
Publikováno v:
Vaccines, Vol 12, Iss 6, p 687 (2024)
Salmonella enterica Serovar Typhi Ty21a (Ty21a) is the only licensed oral vaccine against typhoid fever. Due to its excellent safety profile, it has been used as a promising vector strain for the expression of heterologous antigens for mucosal immuni
Externí odkaz:
https://doaj.org/article/145551d5d640478abeac3f2ca004b08f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in which a bacterial cell becomes insensitive to one (or even) more antibiotic(s). However, the molecular basis for these two antibiotic-tolerant phenotypes is
Externí odkaz:
https://doaj.org/article/70052b7b031f4d8186f35a648bcaf4f1
Autor:
Beat Lehmann, Christine Baumgartner, Laurent Kaiser, Tanja Birrenbach, Christophe Combescure, Jerôme Stirnemann, Olivier Grosgurin, Jean-Luc Reny, Enos Bernasconi, Dina Zekry, Christophe Marti, François Herrmann, Xavier Roux, Pierre-Alexandre Poletti, Antonio Leidi, Virginie Prendki, Nicolas Garin, Alexandra Platon, Thomas Sauter, Wolf Hautz, Gianluca Argentieri, Cristina Boehm-Bosmani, Clémence Cuvelier, Christophe Fehlmann, Pauline Gosselin, Alessandro Jessula, Aileen Kharat, Véronique Lachat, Cornelia Lambrigger, Elisa Marchi, Mihaela Martinvalet, Lara Morosoli, Daniel Ott, Thibault Parent, Frédéric Rouyer, Thomas Ruder, Max Scheffler, Guillaume Soret, Jérôme Tessieras, Catherine Vindret, Enrico Zucconi
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Introduction Pneumonia is a leading cause of mortality and a common indication for antibiotic in elderly patients. However, its diagnosis is often inaccurate. We aim to compare the diagnostic accuracy, the clinical and cost outcomes and the use of an
Externí odkaz:
https://doaj.org/article/cc3a4d70664c4eb8869515a1f89211f3
Autor:
Motaharehsadat Heydarian, Tao Yang, Matthias Schweinlin, Maria Steinke, Heike Walles, Thomas Rudel, Vera Kozjak-Pavlovic
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Gonorrhea is the second most common sexually transmitted infection in the world and is caused by Gram-negative diplococcus Neisseria gonorrhoeae. Since N. gonorrhoeae is a human-specific pathogen, animal infection models are only of limited use. Ther
Externí odkaz:
https://doaj.org/article/b1f675bc5f734a5f802b958888d200b5
Autor:
Annette Fischer, Kelly S Harrison, Yesid Ramirez, Daniela Auer, Suvagata Roy Chowdhury, Bhupesh K Prusty, Florian Sauer, Zoe Dimond, Caroline Kisker, P Scott Hefty, Thomas Rudel
Publikováno v:
eLife, Vol 6 (2017)
Obligate intracellular Chlamydia trachomatis replicate in a membrane-bound vacuole called inclusion, which serves as a signaling interface with the host cell. Here, we show that the chlamydial deubiquitinating enzyme (Cdu) 1 localizes in the inclusio
Externí odkaz:
https://doaj.org/article/b1e8d22bb1f04a32a1e99d57bb057a2f
Autor:
Prema Subbarayal, Karthika Karunakaran, Ann-Cathrin Winkler, Marion Rother, Erik Gonzalez, Thomas F Meyer, Thomas Rudel
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004846 (2015)
The obligate intracellular bacterium Chlamydia trachomatis invades into host cells to replicate inside a membrane-bound vacuole called inclusion. Multiple different host proteins are recruited to the inclusion and are functionally modulated to suppor
Externí odkaz:
https://doaj.org/article/7d8b9436bd9e417a82021dcd5e6b62f5
Autor:
Stefanie Baur, Maren Rautenberg, Michaela Faulstich, Timo Grau, Yannik Severin, Clemens Unger, Wolfgang H Hoffmann, Thomas Rudel, Ingo B Autenrieth, Christopher Weidenmaier
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004089 (2014)
Nasal colonization is a major risk factor for S. aureus infections. The mechanisms responsible for colonization are still not well understood and involve several factors on the host and the bacterial side. One key factor is the cell wall teichoic aci
Externí odkaz:
https://doaj.org/article/504affc46ac54dada6842e3ab00761dc