Zobrazeno 1 - 10
of 710
pro vyhledávání: '"Thomas R, Kosten"'
Autor:
Xingxing Li, Junyao Liu, Shuochi Wei, Chang Yu, Dongmei Wang, Yuchen Li, Jiaxin Li, Wenhao Zhuang, Rui-Chen-Xi Luo, Yanli Li, Zhiwang Liu, Yuqiu Su, Jimeng Liu, Yongming Xu, Jialin Fan, Guidong Zhu, Weiqian Xu, Yiping Tang, Hui Yan, Raymond Y. Cho, Thomas R. Kosten, Dongsheng Zhou, Xiangyang Zhang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Cognitive dysfunction is one of the common symptoms in patients with major depressive disorder (MDD). Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) have been studied separat
Externí odkaz:
https://doaj.org/article/b5951ceb3b7d4528b6272b5e477c063d
Autor:
Paul M. Cinciripini, David W. Wetter, Jian Wang, Robert Yu, George Kypriotakis, Tapsi Kumar, Jason D. Robinson, Yong Cui, Charles E. Green, Andrew W. Bergen, Thomas R. Kosten, Steven E. Scherer, Sanjay Shete
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Despite the large public health toll of smoking, genetic studies of smoking cessation have been limited with few discoveries of risk or protective loci. We investigated common and rare variant associations with success in quitting smoking us
Externí odkaz:
https://doaj.org/article/7508837f9caa4e14ad97cc6863aab246
Autor:
Nicholas Murphy, Grace Pham, Andreas Weyland, Julia Engelhardt, George Kypriotakis, Ynhi T. Thomas, Thomas R. Kosten, Nidal Moukaddam, Sanjay J. Mathew, Alan C. Swann
Publikováno v:
Journal of Affective Disorders Reports, Vol 17, Iss , Pp 100833- (2024)
Background: Studies attempting to distinguish suicide attempters from ideators have found that impulsivity is consistently associated with attempts across the spectrum of suicidal behavior from self-harm to lethal suicidal behavior. Impulsivity is re
Externí odkaz:
https://doaj.org/article/97e4a7a583ca4b4e9553c38e3eb4755b
Autor:
Macarena S. Aloi, Guillermo F. Poblete, John Oldham, Michelle A. Patriquin, David A. Nielsen, Thomas R. Kosten, Ramiro Salas
Publikováno v:
npj Mental Health Research, Vol 2, Iss 1, Pp 1-8 (2023)
Abstract Borderline personality disorder (BPD) is characterized by patterns of unstable affect, unstable interpersonal relationships, and chronic suicidal tendencies. Research on the genetics, epigenetics, and brain function of BPD is lacking. MicroR
Externí odkaz:
https://doaj.org/article/ef3d2517d3b04f0c9e5c6a050e66e4b0
Autor:
Megan J. Shram, Jack E. Henningfield, Glen Apseloff, Charles W. Gorodetzky, Sara De Martin, Frank L. Vocci, Frank L. Sapienza, Thomas R. Kosten, Jeff Huston, August Buchhalter, Judy Ashworth, Ryan Lanier, Franco Folli, Andrea Mattarei, Clotilde Guidetti, Stefano Comai, Cedric O’Gorman, Sergio Traversa, Charles E. Inturrisi, Paolo L. Manfredi, Marco Pappagallo
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Esmethadone (REL-1017) is the opioid-inactive dextro-isomer of methadone and a low-affinity, low-potency uncompetitive NMDA receptor antagonist. In a Phase 2, randomized, double-blind, placebo-controlled trial, esmethadone showed rapid, robu
Externí odkaz:
https://doaj.org/article/b958bfa2946e4409a7e15362350d0462
Autor:
Paul M Cinciripini, Robert Suchting, Luba Yammine, Christopher D Verrico, Francesco Versace, Heather E Webber, Michael F Weaver, Thomas R Kosten, Husein Alibhai, Scott D Lane, Joy M Schmitz
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Introduction Obesity and smoking are the two leading causes of preventable death in the USA. Unfortunately, most smokers gain weight after quitting. Postcessation weight gain (PCWG) is frequently cited as one of the primary barriers to a quit attempt
Externí odkaz:
https://doaj.org/article/15c637f96dfa41168c1ae0a29a88033a
Autor:
Ismene Petrakis, Sandra A. Springer, Cynthia Davis, Elizabeth Ralevski, Lucy Gu, Robert Lew, John Hermos, Melynn Nuite, Adam J. Gordon, Thomas R. Kosten, Edward V. Nunes, Robert Rosenheck, Andrew J. Saxon, Robert Swift, Alexa Goldberg, Robert Ringer, Ryan Ferguson
Publikováno v:
Addiction Science & Clinical Practice, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background To address the US opioid epidemic, there is an urgent clinical need to provide persons with opioid use disorder (OUD) with effective medication treatments for OUD (MOUD). Formulations of sublingual buprenorphine/naloxone (SL-BUP/N
Externí odkaz:
https://doaj.org/article/0cb2d698acd54c03b5ec2d47cca9a316
Autor:
Sandra L. Grimm, Emily F. Mendez, Laura Stertz, Thomas D. Meyer, Gabriel R. Fries, Tanmay Gandhi, Rupa Kanchi, Sudhakar Selvaraj, Antonio L. Teixeira, Thomas R. Kosten, Preethi Gunaratne, Cristian Coarfa, Consuelo Walss-Bass
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
IntroductionTo understand mechanisms and identify potential targets for intervention in the current crisis of opioid use disorder (OUD), postmortem brains represent an under-utilized resource. To refine previously reported gene signatures of neurobio
Externí odkaz:
https://doaj.org/article/30ce589188ff4ac08d007ac66ff28274
Autor:
Jing-Li Yue, Kai Yuan, Yan-Ping Bao, Shi-Qiu Meng, Le Shi, Qing Fang, Xiao-Jie Guo, Lu Cao, Ye-Kun Sun, Tang-Sheng Lu, Na Zeng, Wei Yan, Ying Han, Jie Sun, Jie Shi, Thomas R. Kosten, Yan-Xue Xue, Ping Wu, Lin Lu
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104283- (2022)
Summary: Background: Opioid use disorder (OUD) is a chronic relapsing psychiatric disorder. An unconditioned stimulus (US)-triggers a memory reconsolidation updating procedure (MRUP) that has been developed and demonstrated its effectiveness in decre
Externí odkaz:
https://doaj.org/article/d54d5c796e024312ab0c9539a72e5c7f
Autor:
Claire Morice, Dewleen G. Baker, Marguerite M. Patel, Tracy L. Nolen, Kayla Nowak, Shawn Hirsch, Thomas R. Kosten, Christopher D. Verrico
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract PT150, a novel competitive glucocorticoid receptor (GR) antagonist, has proven safe in animal models, healthy volunteers, and people with depression. Our study is the first to investigate PT150’s safety with alcohol use. The primary object
Externí odkaz:
https://doaj.org/article/0e47702aff834151b977af287dc2a85f