Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas Q. Davies"'
Publikováno v:
Organic Letters. 24:1711-1715
A new N-silyl sulfinylamine reagent allows the rapid preparation of a broad range of (hetero)aryl, alkenyl, and alkyl primary sulfinamides, using Grignard, organolithium, or organozinc reagents to introduce the carbon fragment. Treatment of these pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbe14010d89a35bc6936792d8e6e161
https://doi.org/10.1021/acs.orglett.2c00347
https://doi.org/10.1021/acs.orglett.2c00347
Publikováno v:
Journal of the American Chemical Society
Nickel catalysis allied with cyclodiphosphazane or VAPOL-derived phosphoramidite ligands provides selective access to monoprotected vicinal diols by reductive coupling of dienol ethers and aldehydes. The observed regioselectivity is unprecedented, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c9e119d6c415775eecd4868cf8801d
http://europepmc.org/articles/PMC8414482
http://europepmc.org/articles/PMC8414482
Publikováno v:
Journal of the American Chemical Society
Sulfondiimines—the double aza-analogues of sulfones—hold significant potential as leads in discovery chemistry, yet their application in this arena has been held back by the scarcity of appropriate synthetic routes. Existing methods employ sulfid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f391914c323d3f050d674d6ebcce59be
http://europepmc.org/articles/PMC7007239
http://europepmc.org/articles/PMC7007239
Autor:
Michael C. Willis, Thomas Q. Davies
Publikováno v:
Chemistry – A European Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::074d512f81735f5a7f7da3554ea416b8
https://doi.org/10.1002/chem.202183562
https://doi.org/10.1002/chem.202183562
Publikováno v:
Organic Letters
Sulfonamides have played a defining role in the history of drug development and continue to be prevalent today. In particular, primary sulfonamides are common in marketed drugs. Here we describe the direct synthesis of these valuable compounds from o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a64462cc9957e693b42dfc46b3e641
https://ora.ox.ac.uk/objects/uuid:ee5c2501-a8f0-4de4-8244-e7d16bca8871
https://ora.ox.ac.uk/objects/uuid:ee5c2501-a8f0-4de4-8244-e7d16bca8871
Autor:
Jack Ren, Michael J. Tilby, Adrian Hall, Thomas Q. Davies, Nicholas A. Parker, Michael C. Willis, David Skolc, Fernanda Duarte
Publikováno v:
Journal of the American Chemical Society
Sulfoximines and sulfonimidamides are promising compounds for medicinal and agrochemistry. As monoaza analogues of sulfones and sulfonamides, respectively, they combine good physicochemical properties, high stability, and the ability to build complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b5a24e8db41bf008963b5194107aed
https://pubmed.ncbi.nlm.nih.gov/32841007
https://pubmed.ncbi.nlm.nih.gov/32841007
Publikováno v:
Angewandte Chemie. 129:15133-15137
Sulfonimidamides are increasingly important molecules in medicinal chemistry and agrochemistry, but their preparation requires lengthy synthetic sequences, which has likely limited their use. We describe a one-pot de novo synthesis of sulfonimidamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2567276f59d6ba6a59c8e8077cb2bd
https://doi.org/10.1002/ange.201708590
https://doi.org/10.1002/ange.201708590
Autor:
T. A. Fleming, Melodie S. W. Richardson, A. Borissov, Thomas Q. Davies, Sam R. Ellis, Darren J. Dixon
Publikováno v:
Chem. Soc. Rev.. 45:5474-5540
Organocatalytic enantioselective desymmetrisation of achiral or meso compounds is a powerful strategy for the construction of enantiomerically enriched complex molecules, often with multiple stereocentres and in high selectivities. Recent years have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea9e11d7c2d55a20b025d8e8c2cb320
https://doi.org/10.1039/c5cs00015g
https://doi.org/10.1039/c5cs00015g
Autor:
Darren J. Dixon, T. A. Fleming, Melodie S. W. Richardson, Sam R. Ellis, A. Borissov, Thomas Q. Davies
Publikováno v:
ChemInform. 47
Organocatalytic enantioselective desymmetrisation of achiral or meso compounds is a powerful strategy for the construction of enantiomerically enriched complex molecules, often with multiple stereocentres and in high selectivities. Recent years have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c034ef5c7726a07a1df64842b42e2974
https://doi.org/10.1002/chin.201649234
https://doi.org/10.1002/chin.201649234