Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Thomas Prukop"'
Autor:
Muhammad Rafehi, Frank Faltraco, Johannes Matthaei, Thomas Prukop, Ole Jensen, Aileen Grytzmann, Felix G. Blome, Ralf Günter Berger, Ulrich Krings, Stefan V. Vormfelde, Mladen V. Tzvetkov, Jürgen Brockmöller
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Tyramine, formed by the decarboxylation of tyrosine, is a natural constituent of numerous food products. As an indirect sympathomimetic, it can have potentially dangerous hypertensive effects. In vitro data indicated that the pharmacokinetics of tyra
Externí odkaz:
https://doaj.org/article/f55790e222414a8e9795d76df9fa1ea9
Autor:
Thomas Prukop, Jan Stenzel, Stephanie Wernick, Theresa Kungl, Magdalena Mroczek, Julia Adam, David Ewers, Serguei Nabirotchkin, Klaus-Armin Nave, Rodolphe Hajj, Daniel Cohen, Michael W Sereda
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209752 (2019)
The most common type of Charcot-Marie-Tooth disease is caused by a duplication of PMP22 leading to dysmyelination, axonal loss and progressive muscle weakness (CMT1A). Currently, no approved therapy is available for CMT1A patients. A novel polytherap
Externí odkaz:
https://doaj.org/article/54beea3e92d54d269e68e88861e3c885
Autor:
Giovanna Sociali, Davide Visigalli, Thomas Prukop, Ilaria Cervellini, Elena Mannino, Consuelo Venturi, Santina Bruzzone, Michael W. Sereda, Angelo Schenone
Publikováno v:
Neurobiology of Disease, Vol 95, Iss , Pp 145-157 (2016)
Charcot-Marie-Tooth 1A (CMT1A) is a demyelinating hereditary neuropathy for which pharmacological treatments are not yet available. An abnormally high intracellular Ca2+ concentration was observed in Schwann cells (SC) from CMT1A rats, caused by the
Externí odkaz:
https://doaj.org/article/e0b812583bae437a95e6d60c5edf1094
Autor:
Serguei Nabirotchkin, Lydie Boussicault, Dirk Czesnik, Susanne Quintes, Jana Zschüntzsch, Jens Schmidt, Julia Adam, David Ewers, Michael Bartl, Daniel Cohen, Julien Laffaire, Karoline Jäger, Klaus-Armin Nave, Anthony Brureau, Markus H. Schwab, Alonso Barrantes-Freer, Stephanie Wernick, Michael W. Sereda, Philippe Rinaudo, Thomas Prukop, Gwenaël Primas, Lorenz Winter, Rodolphe Hajj, Lisa Linhoff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445691622dcc0db7869b1ef4b553b8af
https://doi.org/10.1002/jnr.24679/v2/response1
https://doi.org/10.1002/jnr.24679/v2/response1
Autor:
Tina Seitz, Sherin Pojar, Jürgen Brockmöller, Mladen V. Tzvetkov, Frank Faltraco, Sabrina Vogler, Thomas Prukop, Johannes Matthaei
Publikováno v:
Clinical Pharmacology & Therapeutics. 103:868-878
Fenoterol is a widely used anti-asthmatic and tocolytic agent, but high plasma concentrations of fenoterol may lead to severe and even fatal adverse reactions. We studied whether heritable deficiency of the liver organic cation transporter 1 (OCT1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a273d7daf476c3648510a1e297d1df4
https://doi.org/10.1002/cpt.812
https://doi.org/10.1002/cpt.812
Autor:
S Thiele, E Akova-Öztürk, E Greckl, S Fritzsch, Beate Schlotter-Weigel, L Reinecke, Thomas Prukop, Michael W. Sereda, Maggie C. Walter, B Dräger, Peter Young, N Garcia-Angarita, Robert Fledrich
Publikováno v:
Nervenheilkunde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ac36072cf50861c9f83bd43efc9aae
https://doi.org/10.1055/s-0039-1685012
https://doi.org/10.1055/s-0039-1685012
Autor:
E Akova-Öztürk, B Dräger, Beate Schlotter-Weigel, S Fritzsch, L Reinecke, S Thiele, Michael W. Sereda, Peter Young, E Greckl, Burkhard Gess, Thomas Prukop, N Garcia-Angarita, Maggie C. Walter, Maike F. Dohrn
Publikováno v:
Nervenheilkunde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc952766b852e36cf2ddc170d535a94
https://doi.org/10.1055/s-0039-1685099
https://doi.org/10.1055/s-0039-1685099
Autor:
Annabelle Tann, Tina Seitz, Mladen V. Tzvetkov, Jürgen Brockmöller, Thomas Prukop, Ole Jensen, Johannes Matthaei, Sina Tadjerpisheh
Publikováno v:
Clinical pharmacology and therapeutics. 105(1)
Cycloguanil, the active metabolite of proguanil, acts on malaria schizonts in erythrocytes and hepatocytes. We analyzed the impact of the organic cation transporter OCT1 on hepatocellular uptake and pharmacokinetics of proguanil and cycloguanil. OCT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2abe82a7196364fffa81a653ec3dcbe
https://pubmed.ncbi.nlm.nih.gov/29882324
https://pubmed.ncbi.nlm.nih.gov/29882324
Autor:
Tim Beissbarth, Pavel Seeman, José Berciano, Radim Mazanec, Jana Haberlová, Jean-Yves Hogrel, Ana L. Pelayo-Negro, Rita Horvath, Robert Fledrich, Michael E. Shy, Peter Young, Walter Paulus, Davide Pareyson, Beate Schlotter-Weigel, Alessandra Solari, Dirk Czesnik, Thomas Prukop, Michael W. Sereda, Angelo Schenone, Maggie C. Walter, Tuuli J. Schnizer, Cmt Triaal, Manoj Mannil, Peter De Jonghe, Odile Dubourg, Natalia Garcia-Angarita, Andreas Leha, Caroline Ehbrecht, Jonathan Baets
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry
J Neurol Neurosurg Psychiatry
Journal of neurology, neurosurgery and psychiatry
J Neurol Neurosurg Psychiatry
Journal of neurology, neurosurgery and psychiatry
Background Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common inherited neuropathy, a debilitating disease without known cure. Among patients with CMT1A, disease manifestation, progression and severity are strikingly variable, which poses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca65d919782eca4816236e202ca7314
https://hdl.handle.net/11858/00-001M-0000-002E-080F-911858/00-001M-0000-002E-080D-D21.11116/0000-000D-3088-3
https://hdl.handle.net/11858/00-001M-0000-002E-080F-911858/00-001M-0000-002E-080D-D21.11116/0000-000D-3088-3
Autor:
Mladen V, Tzvetkov, Johannes, Matthaei, Sherin, Pojar, Frank, Faltraco, Sabrina, Vogler, Thomas, Prukop, Tina, Seitz, Jürgen, Brockmöller
Publikováno v:
Clinical pharmacology and therapeutics. 103(5)
Fenoterol is a widely used anti-asthmatic and tocolytic agent, but high plasma concentrations of fenoterol may lead to severe and even fatal adverse reactions. We studied whether heritable deficiency of the liver organic cation transporter 1 (OCT1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b10717f9f546e48fe42f0df09f3ec299
https://pubmed.ncbi.nlm.nih.gov/28791698
https://pubmed.ncbi.nlm.nih.gov/28791698