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Autor:
Sean M. Colvin, Daniel L. Rudnicki, David J. Burkhart, Benjamin L. Barthel, Tad H. Koch, Thomas Price Kirby
Publikováno v:
Journal of Medicinal Chemistry. 55:6595-6607
Doxazolidine (doxaz) is a new anthracycline anticancer agent. While structurally similar to doxorubicin (dox), doxaz acts via a distinct mechanism to selectively enhance anticancer activity over cardiotoxicity, the most significant clinical impedimen