Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Thomas Pleli"'
Autor:
Oliver Waidmann, Thomas Pleli, Andreas Weigert, Esther Imelmann, Bianca Kakoschky, Christian Schmithals, Claudia Döring, Matthias Frank, Thomas Longerich, Verena Köberle, Martin-Leo Hansmann, Bernhard Brüne, Stefan Zeuzem, Albrecht Piiper, Ivan Dikic
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract The nuclear factor kappa beta (NFκB) signaling pathway plays an important role in liver homeostasis and cancer development. Tax1-binding protein 1 (Tax1BP1) is a regulator of the NFκB signaling pathway, but its role in the liver and hepato
Externí odkaz:
https://doaj.org/article/740d319af09b47b9b936f1021dead416
Autor:
Thomas Pleli, Antonia Mondorf, Nerea Ferreiros, Dominique Thomas, Karel Dvorak, Ricardo M. Biondi, Dagmar Meyer zu Heringdorf, Stefan Zeuzem, Gerd Geisslinger, Herbert Zimmermann, Oliver Waidmann, Albrecht Piiper
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 6, Pp 2516-2528 (2018)
Background/Aims: Signaling of Gs protein-coupled receptors (GsPCRs) is accomplished by stimulation of adenylyl cyclase, causing an increase of the intracellular cAMP concentration, activation of the intracellular cAMP effectors protein kinase A (PKA)
Externí odkaz:
https://doaj.org/article/0a4e904e6a144be5903bf729f11e5b78
Autor:
Bianca Kakoschky, Thomas Pleli, Christian Schmithals, Stefan Zeuzem, Bernhard Brüne, Thomas J Vogl, Horst-Werner Korf, Andreas Weigert, Albrecht Piiper
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193015 (2018)
Tumor progression largely depends on the presence of alternatively polarized (M2) tumor-associated macrophages (TAMs), whereas the classical M1-polarized macrophages can promote anti-tumorigenic immune responses. Thus, selective inhibition of M2-TAMs
Externí odkaz:
https://doaj.org/article/4bd020232e2f487b86c471e6052402e8
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Cytokine regulation of high-output nitric oxide (NO) derived from inducible NO synthase (iNOS) is critically involved in inflammation biology and host defense. Herein, we set out to characterize the role of type I interferon (IFN) as potential regula
Externí odkaz:
https://doaj.org/article/6d72a8d13f944be7a415f07cfccc0907
Autor:
Tivadar Feczkó, Albrecht Piiper, Thomas Pleli, Christian Schmithals, Dominic Denk, Stephanie Hehlgans, Franz Rödel, Thomas J. Vogl, Matthias G. Wacker
Publikováno v:
Pharmaceutics, Vol 11, Iss 10, p 489 (2019)
Today, efficient delivery of sorafenib to hepatocellular carcinoma remains a challenge for current drug formulation strategies. Incorporating the lipophilic molecule into biocompatible and biodegradable theranostic nanocarriers has great potential fo
Externí odkaz:
https://doaj.org/article/5ecb77e3652d4e2e8b12786867315b7c
Autor:
Jörg Haupenthal, Verena Bihrer, Huedayi Korkusuz, Otto Kollmar, Christian Schmithals, Susanne Kriener, Knut Engels, Thomas Pleli, Alexander Benz, Marta Canamero, Thomas Longerich, Bernd Kronenberger, Swantje Richter, Oliver Waidmann, Thomas J. Vogl, Stefan Zeuzem, Albrecht Piiper
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 5, Pp 410-419 (2012)
Highly promising preclinical data obtained in cultured cells and in nude mice bearing xenografts contrast with the rather modest clinical efficacy of Polo-like kinase 1 (Plk1) inhibitors. In the present study, we investigated if Plk1 might be a suita
Externí odkaz:
https://doaj.org/article/d3b8209be09c43399674c73761c95564
Autor:
Thomas Pleli, Daniel Martin, Bernd Kronenberger, Friederike Brunner, Verena Köberle, Georgios Grammatikos, Harald Farnik, Yolanda Martinez, Fabian Finkelmeier, Sandra Labocha, Nerea Ferreirós, Stefan Zeuzem, Albrecht Piiper, Oliver Waidmann
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103532 (2014)
BackgroundAutotaxin (ATX) and its product lysophosphatidic acid (LPA) are considered to be involved in the development of liver fibrosis and elevated levels of serum ATX have been found in patients with hepatitis C virus associated liver fibrosis. Ho
Externí odkaz:
https://doaj.org/article/f85ff14292e741c48d9e01f2f8ef19b1
Autor:
Verena Köberle, Thomas Pleli, Christian Schmithals, Eduardo Augusto Alonso, Jörg Haupenthal, Halvard Bönig, Jan Peveling-Oberhag, Ricardo M Biondi, Stefan Zeuzem, Bernd Kronenberger, Oliver Waidmann, Albrecht Piiper
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75184 (2013)
BACKGROUND: MicroRNAs circulating in the blood, stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles, are currently being evaluated as biomarkers. The consequences of their differential association with lipi
Externí odkaz:
https://doaj.org/article/27cc2e82207f44788788a7973b7c1911
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Supplementary Fig. S3. Doxycyline-induced overexpression of Dicer in HCC cells. HepG2 (A) and Huh-7 (B) cells stably transfected with the inducible Dicer construct were incubated with or without doxycycline (Dox) for 24 h. C: HepG2 cells with the ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153173b78795cd01540a4b2857d672af
https://doi.org/10.1158/1078-0432.22466477.v1
https://doi.org/10.1158/1078-0432.22466477.v1
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Table S1. Clinicopathological parameters of the patients with HCC. HBV, hepatitis B virus; HCV, hepatitis C virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6865ed66d510950ea5367a566e7d6f
https://doi.org/10.1158/1078-0432.22466471
https://doi.org/10.1158/1078-0432.22466471