Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Thomas Pietschmann"'
Autor:
Carina R. Hartmann, Robin Khan, Jennifer Schöning, Maximilian Richter, Maike Willers, Sabine Pirr, Julia Heckmann, Johannes Dirks, Henner Morbach, Monika Konrad, Elena Fries, Magdalene Winkler, Johanna Büchel, Silvia Seidenspinner, Jonas Fischer, Claudia Vollmuth, Martin Meinhardt, Janina Marissen, Mirco Schmolke, Sibylle Haid, Thomas Pietschmann, Simone Backes, Lars Dölken, Ulrike Löber, Thomas Keil, Peter U. Heuschmann, Achim Wöckel, Sagar, Thomas Ulas, Sofia K. Forslund-Startceva, Christoph Härtel, Dorothee Viemann
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRespiratory viral infections (RVIs) are a major global contributor to morbidity and mortality. The susceptibility and outcome of RVIs are strongly age-dependent and show considerable inter-population differences, pointing to genetically a
Externí odkaz:
https://doaj.org/article/9f360bbb7f334dfd8f295291a1345444
Autor:
Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infection in infants, older adults and the immunocompromised. Effective directly acting antivirals are not yet available for clinical use. To address this,
Externí odkaz:
https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4
Autor:
Chris Lauber, Xiaoyu Zhang, Josef Vaas, Franziska Klingler, Pascal Mutz, Arseny Dubin, Thomas Pietschmann, Olivia Roth, Benjamin W Neuman, Alexander E Gorbalenya, Ralf Bartenschlager, Stefan Seitz
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012163 (2024)
Virus discovery by genomics and metagenomics empowered studies of viromes, facilitated characterization of pathogen epidemiology, and redefined our understanding of the natural genetic diversity of viruses with profound functional and structural impl
Externí odkaz:
https://doaj.org/article/d84e98e452c042e5b5e193235d7e40a8
Autor:
Alina Matthaei, Sebastian Joecks, Annika Frauenstein, Janina Bruening, Dorothea Bankwitz, Martina Friesland, Gisa Gerold, Gabrielle Vieyres, Lars Kaderali, Felix Meissner, Thomas Pietschmann
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTAssembly of infectious hepatitis C virus (HCV) particles requires multiple cellular proteins including for instance apolipoprotein E (ApoE). To describe these protein-protein interactions, we performed an affinity purification mass spectromet
Externí odkaz:
https://doaj.org/article/376bdc7a189e4ffe9567f56ee0bc03d1
Autor:
Yannick Stahl, Iyad Kabar, Hauke Heinzow, Benjamin Maasoumy, Birgit Bremer, Heiner Wedemeyer, Hartmut H.-J. Schmidt, Thomas Pietschmann, Bernhard Schlevogt, Patrick Behrendt
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Hepatitis E virus (HEV) is the leading cause of acute viral hepatitis. Numerous studies have investigated the dynamics of HEV infection markers, but the most suitable marker for diagnosing ongoing or recent HEV infection remains to be determined. Rec
Externí odkaz:
https://doaj.org/article/4bd99d018d8f4f499d2695a8b3e51829
Autor:
Yudi Zhang, Volker Kinast, Julie Sheldon, Nicola Frericks, Daniel Todt, Matthias Zimmer, Neva Caliskan, Richard J. P. Brown, Eike Steinmann, Thomas Pietschmann
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Mice are refractory to infection with human-tropic hepatitis C virus (HCV), although distantly related rodent hepaciviruses (RHV) circulate in wild rodents. To investigate whether liver intrinsic host factors can exhibit broad restriction ag
Externí odkaz:
https://doaj.org/article/49181b3ec16a43678eaa9634d45b4129
Autor:
Claas Baier, Jiabin Huang, Kerstin Reumann, Daniela Indenbirken, Felicitas Thol, Christian Koenecke, Ella Ebadi, Albert Heim, Franz-Christoph Bange, Sibylle Haid, Thomas Pietschmann, Nicole Fischer
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-8 (2022)
Abstract Background Respiratory syncytial virus (RSV) causes community-acquired respiratory tract infections during winter. However, outbreaks in hospitals also occur repeatedly. In particular, patients with hematologic malignancies are at an increas
Externí odkaz:
https://doaj.org/article/aef408e9daed4a1789df9b5a317daa31
IRIS: Infection with RespIratory Syncytial Virus in infants—a prospective observational cohort study
Autor:
Martin Wetzke, Dominik Funken, Mathias Lange, Levente Bejo, Sibylle Haid, Joao G. Tereno Monteiro, Katharina Schütz, Christine Happle, Thomas F. Schulz, Jürgen Seidenberg, Thomas Pietschmann, Gesine Hansen
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infection in infants. Globally, RSV is responsible for approximately 3.2 million hospital admissions and about 60,000 in-hospital deaths p
Externí odkaz:
https://doaj.org/article/e34e544a12a84b7c9490fe577c5eb96d
Autor:
Francisco J. Zapatero-Belinchón, Rebecca Moeller, Lisa Lasswitz, Marco van Ham, Miriam Becker, Graham Brogden, Ebba Rosendal, Wenjie Bi, Belén Carriquí-Madroñal, Koushikul Islam, Annasara Lenman, Antonia P. Gunesch, Jared Kirui, Thomas Pietschmann, Anna K. Överby, Lothar Jänsch, Gisa Gerold
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103469- (2021)
Summary: Clinical data of patients suffering from COVID-19 indicates that statin therapy, used to treat hypercholesterolemia, is associated with a better disease outcome. Whether statins directly affect virus replication or influence the clinical out
Externí odkaz:
https://doaj.org/article/34bc37bb80fe4e8db30733cdbb761e1b
Autor:
Xavier Martin-Benlloch, Sibylle Haid, Alexandra Novodomska, Frank Rominger, Thomas Pietschmann, Elisabeth Davioud-Charvet, Mourad Elhabiri
Publikováno v:
ACS Omega, Vol 4, Iss 3, Pp 4871-4887 (2019)
Externí odkaz:
https://doaj.org/article/1df6080d6ccd44d8ba701521bdd5618d