Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Thomas Perrotton"'
Autor:
Xiu Bao Chang, Attilio Di Pietro, Hélène Baubichon-Cortay, Doriane Trompier, Thomas Perrotton
Publikováno v:
The Journal of biological chemistry. 282(43)
The multidrug-resistant protein MRP1 (involved in the cancer cell multidrug resistance phenotype) has been found to be modulated by racemic verapamil (through stimulation of glutathione transport), inducing apoptosis of human MRP1 cDNA-transfected ba
Autor:
Hélène Baubichon-Cortay, Doriane Trompier, Ahcène Boumendjel, Thomas Perrotton, Attilio Di Pietro
Publikováno v:
Medicinal research reviews. 25(4)
Multidrug resistance protein 1 (MRP1) belongs to the ATP-binding cassette (ABC) transporter family. It is able to transport a broad range of anticancer drugs through cellular membranes, thus limiting their antiproliferative action. Since its discover
Autor:
Thomas Perrotton, Laurent Nault, Antoine Leydier, Celine Girardot, Anthony W. Coleman, Sandrine Magnard, Hélène Baubichon-Cortay
Publikováno v:
New Journal of Chemistry. 34:1812
The tri-carboxylatomethylene-mono-alkoxy calix[4]arenes have been shown by fluorescence spectroscopy to bind to the NBD1 domain of MRP1 protein in a magnesium dependent manner. The observed associations constants are of the same order as that observe