Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thomas P. Perry"'
Autor:
Yun Deng, Thomas A Perry, Philippa Hulley, Rose A Maciewicz, Joanna Mitchelmore, Darryl Perry, Staffan Larsson, Sophie Brachat, André Struglics, C Thomas Appleton, Stefan Kluzek, Nigel K Arden, David Felson, Brian Marsden, Brian D M Tom, Laura Bondi, Mohit Kapoor, Vicky Batchelor, Jennifer Mackay-Alderson, Vinod Kumar, L Stefan Lohmander, Tim J Welting, David A Walsh, Ana M Valdes, STEpUP OA Consortium, Tonia L Vincent, Fiona E Watt, Luke Jostins-Dean
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0309677 (2024)
ObjectivesTo develop a protocol for largescale analysis of synovial fluid proteins, for the identification of biological networks associated with subtypes of osteoarthritis.MethodsSynovial Fluid To detect molecular Endotypes by Unbiased Proteomics in
Externí odkaz:
https://doaj.org/article/1a7b992e033f487392bdc5e67be7b7f1
Autor:
Thomas J. Perry, II, BS, Timur P. Sarac, MD, Kristine Orion, MD, John Bozinovski, MD, Mounir Haurani, MD, Bryan W. Tillman, MD, PhD
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 8, Iss 4, Pp 664-666 (2022)
The use of thoracic endovascular aortic repair for thoracic aortic disease will necessitate cervical debranching in cases involving the proximal arch. We have presented the case of a 57-year-old athletic woman who had developed a type A dissection th
Externí odkaz:
https://doaj.org/article/593afcbd3ac4440eb9815b8fb7288a4c
Autor:
Ken Bassett, James Wright, Leire Leache, Luis Carlos Saiz, Juan Erviti, Thomas L Perry, Mohamed Ben-Eltriki, Ciprian Jauca, Marta Gutiérrez-Valencia
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Objective The FOURIER trial showed a benefit of the PCSK9 inhibitor evolocumab over placebo with respect to cardiovascular outcomes in patients with cardiovascular disease. However, we observed some inconsistencies between the information in the Clin
Externí odkaz:
https://doaj.org/article/5d027055f3104f3781f0b09137eb99c7
Autor:
Heungdeok Kim, Jinwon Seo, Yunsin Lee, Kiwon Park, Thomas A. Perry, Nigel K. Arden, Ali Mobasheri, Heonsik Choi
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 14 (2022)
In this narrative review article, we critically assess the current state of the osteoarthritis (OA) drug development pipeline. We discuss the current state-of-the-art in relation to the development and evaluation of candidate disease-modifying OA dru
Externí odkaz:
https://doaj.org/article/bab948fc343549e5858f58982515eba1
Autor:
Thomas A. Perry, Charlotte Dando, Tim D. Spector, Deborah J. Hart, Catherine Bowen, Nigel Arden
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 9, Pp 614-621 (2021)
Objective Our aims were to examine the effects of heeled shoes on incident knee osteoarthritis (OA) and joint pain. Methods We used longitudinal data from the Chingford 1000 Women Study (Chingford Study), a prospective cohort of women aged 50 years o
Externí odkaz:
https://doaj.org/article/18f75b66d3a44b5db026b4b5caa2ac0c
Autor:
Anne-Xander van der Stel, Emily R. Gordon, Arnab Sengupta, Allyson K. Martínez, Dorota Klepacki, Thomas N. Perry, Alba Herrero del Valle, Nora Vázquez-Laslop, Matthew S. Sachs, Luis R. Cruz-Vera, C. Axel Innis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Bacteria adjust the expression of some of their metabolic enzymes through metabolite-sensing ribosome nascent chain complexes. Here the authors present a cryo-EM structure of an E. coli ribosome stalled during translation of the TnaC leader peptide a
Externí odkaz:
https://doaj.org/article/99346a81e0d045cab5ff4b2e4b54f7d9
Autor:
Thomas A. Perry, Neil A. Segal
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 3, Pp 100272- (2022)
Objective: Cryoneurolysis, cold-induced reversible conduction block of peripheral nerves, is an effective treatment for reducing knee osteoarthritis (OA) symptoms and opioid use following knee arthroplasty. There are however, limited data concerning
Externí odkaz:
https://doaj.org/article/cc1ed184366a431a8e33788a4e748daa
Autor:
Xia Wang, Thomas A Perry, Jimmy Caroupapoullé, Alexander Forrester, Nigel K Arden, David J Hunter
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Physical activity (PA) is important to general health and knee osteoarthritis (OA). Excessive workplace PA is an established risk factor for knee OA however, appropriate methods of measurement are unclear. There is a need to exami
Externí odkaz:
https://doaj.org/article/7bb5b065f4534689899a92ca38d917e6
Autor:
Thomas A. Perry, Alan Silman, David Culliford, Lucy Gates, Nigel Arden, Catherine Bowen, the International Ankle Arthroplasty Registry Consortium
Publikováno v:
Journal of Foot and Ankle Research, Vol 15, Iss 1, Pp n/a-n/a (2022)
Abstract Background Ankle arthroplasty, commonly known as ankle replacement, is a surgical procedure for treating end‐stage ankle osteoarthritis. Whilst evidence shows good clinical results after surgery, little is known of the long‐term survival
Externí odkaz:
https://doaj.org/article/3b5f584e639043d38901f9d8edefa03c
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 4, Pp 100210- (2021)
Objectives: To examine whether foot and/or ankle pain increases the risk of knee OA. Design: We utilised longitudinal data from the Multicentre Osteoarthritis Study (MOST); a community-based cohort of risk factors for knee OA. Participants without fr
Externí odkaz:
https://doaj.org/article/a1a4b9f2c28d439d8bb2f256bb27788f