Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thomas P. Laughren"'
Autor:
Christina R. Chow, Eric Burroughs Jordie, Conrad Housand, Thomas P. Laughren, Ahmed Elmokadem, Christopher D. Bruno, David J. Greenblatt
Publikováno v:
The Journal of Clinical Pharmacology. 62:55-65
Brexpiprazole is an oral antipsychotic agent indicated for use in patients with schizophrenia or as adjunctive treatment for major depressive disorder. As obesity (body mass index ≥35 kg/m2 ) has the potential to affect drug pharmacokinetics and is
Autor:
Thomas P. Laughren
Publikováno v:
The Journal of Clinical Psychiatry. 81
Autor:
Earle Bain, Thomas M. Shiovitz, Thomas P. Laughren, Daniel Burch, Phil Skolnick, Adam Hanina, David J. McCann
Publikováno v:
Journal of Clinical Pharmacology
Accounting for subject nonadherence and eliminating inappropriate subjects in clinical trials are critical elements of a successful study. Nonadherence can increase variance, lower study power, and reduce the magnitude of treatment effects. Inappropr
Publikováno v:
The Journal of clinical psychiatry. 74(10)
Autor:
Richard S E, Keefe, Helena C, Kraemer, Robert S, Epstein, Ellen, Frank, Ginger, Haynes, Thomas P, Laughren, James, McNulty, Shelby D, Reed, Juan, Sanchez, Andrew C, Leon
Publikováno v:
Innovations in clinical neuroscience. 10(5-6 Suppl)
This article captures the proceedings of a meeting aimed at defining clinically meaningful effects for use in randomized controlled trials for psychopharmacological agents.Experts from a variety of disciplines defined clinically meaningful effects fr
Publikováno v:
Pharmacoepidemiology and drug safety. 21(7)
Autor:
Thomas P. Laughren, Walter A. Brown
Publikováno v:
Psychiatry Research. 5:317-322
Following the rise in serum prolactin at the onset of neuroleptic treatment, patients kept on a constant dose show systematic changes in prolactin during the first 3 months. After 4 months, prolactin reaches a stable level substantially lower than th
Autor:
Stephen V. Faraone, Walter A. Brown, Robert Johnston, Frank J. Faltus, Thomas P. Laughren, James P. Curran
Publikováno v:
Psychiatry Research. 19:311-322
Serum neuroleptic levels, prolactin levels, and clinical state were assessed for 1 year in 29 schizophrenic outpatients whose clinically determined neuroleptic dose had been reduced by 50%. Fifty-five percent of the subjects remained stable. Neurolep
Publikováno v:
Computers and biomedical research, an international journal. 10(2)
This paper reports the results of a study to develop and pilot test a system for screening potential suicide attemptors. The system includes a computer interview of patients complaining of suicidal thoughts and Bayesian processing (using subjective p