Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Thomas P. Harrison"'
Autor:
Thomas J. Bracegirdle, Thomas Caton Harrison, Caroline R. Holmes, Hua Lu, Patrick Martineau, Tony Phillips
Publikováno v:
npj Climate and Atmospheric Science, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract In this study, available large ensemble datasets in the Coupled Model Intercomparison Phase 6 (CMIP6) archive were used to provide the first multi-variate overview of the evolution of extreme seasons over Antarctica and the Southern Ocean du
Externí odkaz:
https://doaj.org/article/62a2f7fa96554b2fa02030ee26a8edc6
Autor:
Thomas E Harrison, Nawsad Alam, Brendan Farrell, Doris Quinkert, Amelia M Lias, Lloyd D W King, Lea K Barfod, Simon J Draper, Ivan Campeotto, Matthew K Higgins
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2539-2559 (2024)
Abstract There is an urgent need for improved malaria vaccine immunogens. Invasion of erythrocytes by Plasmodium falciparum is essential for its life cycle, preceding symptoms of disease and parasite transmission. Antibodies which target PfRH5 are hi
Externí odkaz:
https://doaj.org/article/b942500814154714b2e7a3f058d0d828
Autor:
Babula Jena, John Turner, Tylei Reeves-Francois, C. C Bajish, Caroline Holmes, Thomas Caton Harrison, Tony Phillips, Zhaomin Wang
Publikováno v:
npj Climate and Atmospheric Science, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract We investigate an unusual extensive ice-free feature (EIF) within the pack ice that developed in the central Weddell Sea in December 1980 on the edge of the multi-year sea ice off the east coast of the Antarctic Peninsula. The EIF was first
Externí odkaz:
https://doaj.org/article/cd6a80835fe64858937185ed82f633e3
Autor:
Tadeo Kiiza Kandole, Michael Okirwoth, Thomas S. Harrison, Fiona Cresswel, Katherine Fielding, David Moore, David Boulware, David Meya, Joseph N. Jarvis, Jayne Ellis, Enock Kagimu, Laura Nsangi, Gila Hale, Ananta Bangdiwala, Timothy Mugabi, Jane Gakuru, Asmus Tukundane, Enos Kigozi
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background Mortality associated with HIV-associated cryptococcal meningitis remains high even in the context of clinical trials (24–45% at 10 weeks); mortality at 12-months is up to 78% in resource limited settings. Co-prevalent tuberculosis (TB) i
Externí odkaz:
https://doaj.org/article/be66e824ef7a4c3d83a5fe4fc0d45a61
Autor:
David S. Lawrence, Agnes Ssali, Neo Moshashane, Georgina Nabaggala, Lebogang Maphane, Thomas S. Harrison, David Meya, Joseph N. Jarvis, Janet Seeley
Publikováno v:
SSM: Qualitative Research in Health, Vol 4, Iss , Pp 100350- (2023)
HIV-associated cryptococcal meningitis remains a key driver of AIDS-related mortality. Mortality is twice as high in those who present later to care and with severe symptoms such as confusion. We embedded a qualitative methods study within a randomis
Externí odkaz:
https://doaj.org/article/5d46d24a20734857a77e00e6a18fe64d
Autor:
Tom A. Yates, Katie Devlin, Abed Arnaout, William Hurt, Neil Stone, Kate V. Everett, Alan Pittman, Hardik Patel, Susan Heenan, Paul Hart, Thomas S. Harrison
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-8 (2023)
Abstract Background Malakoplakia is a rare condition characterized by inflammatory masses with specific histological characteristics. These soft tissue masses can mimic tumors and tend to develop in association with chronic or recurrent infections, t
Externí odkaz:
https://doaj.org/article/c0d68379c8eb4152937eb2a18f78d490
Autor:
Neil A. R. Gow, Carolyn Johnson, Judith Berman, Alix T. Coste, Christina A. Cuomo, David S. Perlin, Tihana Bicanic, Thomas S. Harrison, Nathan Wiederhold, Mike Bromley, Tom Chiller, Keegan Edgar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The impact of fungal infections on human health has been exacerbated by the rise of antifungal drug resistance. In this Review, the authors outline the problem of antifungal resistance and suggest how this growing threat might be mitigated.
Externí odkaz:
https://doaj.org/article/efbffdf560774198a7369240dd064d59
Autor:
David S Lawrence, Agnes Ssali, Neo Moshashane, Georgina Nabaggala, Lebogang Maphane, Thomas S Harrison, David B Meya, Joseph N Jarvis, Janet Seeley
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010825 (2022)
BackgroundThe AMBITION-cm trial for HIV-associated cryptococcal meningitis demonstrated that a single, high-dose of liposomal amphotericin (AmBisome) plus 14-days of oral flucytosine and fluconazole was non-inferior in terms of all-cause mortality to
Externí odkaz:
https://doaj.org/article/0152e3e136a94921a4024b6f2e795248
Autor:
Ying-Kui Jiang, Rui-Ying Wang, Ling-Hong Zhou, Jia-Hui Cheng, Yu Luo, Rong-Sheng Zhu, Wen-Jia Qiu, Hua-Zhen Zhao, Xuan Wang, Thomas Stephen Harrison, Li-Ping Zhu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The cerebrospinal fluid (CSF) immune responses in HIV-uninfected cryptococcal meningitis (CM) have not been well studied. In this study, we aimed to explore the phenotype of CSF immune response during the course of disease and to examine relationship
Externí odkaz:
https://doaj.org/article/986bbfd771da4aa3b2b13868492f4f30
Autor:
Maria Giorgalli, Deirdre A. Cunningham, Malgorzata Broncel, Aaron Sait, Thomas E. Harrison, Caroline Hosking, Audrey Vandomme, Sarah I. Amis, Ana Antonello, Lauren Sullivan, Faith Uwadiae, Laura Torella, Matthew K. Higgins, Jean Langhorne
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Plasmodium multigene families are thought to play important roles in the pathogenesis of malaria. Plasmodium interspersed repeat (pir) genes comprise the largest multigene family in many Plasmodium species. However, their expression pattern and local
Externí odkaz:
https://doaj.org/article/fdfc5059f3df4ec5b76c252da4225093