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pro vyhledávání: '"Thomas P. Curtin"'
Autor:
Greg J Hermann, Emily Scavarda, Allison M Weis, Daniel S Saxton, Laura L Thomas, Rebecca Salesky, Hannah Somhegyi, Thomas P Curtin, Alec Barrett, Olivia K Foster, Annalise Vine, Katherine Erlich, Elizabeth Kwan, Beverley M Rabbitts, Kaila Warren
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43043 (2012)
The human disease Hermansky-Pudlak syndrome results from defective biogenesis of lysosome-related organelles (LROs) and can be caused by mutations in subunits of the BLOC-1 complex. Here we show that C. elegans glo-2 and snpn-1, despite relatively lo
Externí odkaz:
https://doaj.org/article/60d7b6b7cb714b1da186bfbe8d8edcaa
Autor:
Greg J. Hermann, Hannah Somhegyi, Thomas P. Curtin, Daniel S. Saxton, Annalise Vine, Rebecca Salesky, Olivia K. Foster, Jared L. Delahaye
Publikováno v:
Molecular Biology of the Cell
This work presents a systematic analysis of how VPS-C/HOPS, CCZ-1/SAND-1, and RAB-7, which have well-defined roles in lysosome formation, act in the biogenesis of Caenorhabditis elegans lysosome-related organelles. It identifies key molecular similar