Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas P. Capizzi"'
Autor:
Ji Zhang, Thomas P. Capizzi
Publikováno v:
Drug Information Journal. 30:949-956
In clinical trials with multiple primary endpoints, the effectiveness of a treatment may be established using either a composite endpoint or by employing a decision rule based on the individual end...
Autor:
Helmut W. Minne, Murray J. Favus, Johann Broll, Jan Dequeker, Thomas P. Capizzi, Hui Quan, Arthur C. Santora, Stuart R. Weiss, Raksha V. Shah, Robert W. Downs, Uri A. Liberman, Laurence J. Hirsch, Ego Seeman, Jose Adolfo Rodriguez-Portales, Robert R. Recker, David B. Karpf, Antonio Lombardi, Norman H. Bell
Publikováno v:
New England Journal of Medicine. 333:1437-1444
Background Postmenopausal osteoporosis is a serious health problem, and additional treatments are needed. Methods We studied the effects of oral alendronate, an aminobisphosphonate, on bone mineral density and the incidence of fractures and height lo
Publikováno v:
Communications in Statistics - Theory and Methods. 23:467-484
Many clinical trials involve two-stage sequential designs with one interim analysis (Elashoff and Reedy, 1984, Biometrics 41, 791-795.) In this paper we present a situation where events are counted only at two fixed calendar time points and some pati
Autor:
Hui Quan, Thomas P. Capizzi
Publikováno v:
Biometrics. 55(2)
Studies using a series of increasing doses of a compound, including a zero dose control, are often conducted to study the effect of the compound on the response of interest. For a one-way design, Tukey et al. (1985, Biometrics 41, 295-301) suggested
Publikováno v:
Controlled Clinical Trials. 16:93S-94S
Publikováno v:
Controlled Clinical Trials. 16:51S
Publikováno v:
Controlled Clinical Trials. 14:445
Publikováno v:
Journal of Pharmaceutical Sciences. 72:995-999
A method is provided for estimating the area under a response-time curve for an experimental situation where independent observations are made at each time point. The procedure utilizes least-squares spline functions and the jackknife technique to pr
Publikováno v:
Environmental Science & Technology. 19:35-43
Amelioration de l'evaluation de la concentration ne provoquant pas d'effets observables dans les tests de toxicite chronique
Publikováno v:
Marine Environmental Research. 4:267-278
Weight specific oxygen consumption (Q O 2 ) patterns of the amphipod, Gammarus sp. (acclimated to 5°, 15° and 25°C) and of juvenile blue crabs, Callinectes sapidus (15° and 25°C) were used to evaluate the potential effect of exposure to rapid te