Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Thomas P Slavin"'
Autor:
Elena Vigorito, Karoline B Kuchenbaecker, Jonathan Beesley, Julian Adlard, Bjarni A Agnarsson, Irene L Andrulis, Banu K Arun, Laure Barjhoux, Muriel Belotti, Javier Benitez, Andreas Berger, Anders Bojesen, Bernardo Bonanni, Carole Brewer, Trinidad Caldes, Maria A Caligo, Ian Campbell, Salina B Chan, Kathleen B M Claes, David E Cohn, Jackie Cook, Mary B Daly, Francesca Damiola, Rosemarie Davidson, Antoine de Pauw, Capucine Delnatte, Orland Diez, Susan M Domchek, Martine Dumont, Katarzyna Durda, Bernd Dworniczak, Douglas F Easton, Diana Eccles, Christina Edwinsdotter Ardnor, Ros Eeles, Bent Ejlertsen, Steve Ellis, D Gareth Evans, Lidia Feliubadalo, Florentia Fostira, William D Foulkes, Eitan Friedman, Debra Frost, Pragna Gaddam, Patricia A Ganz, Judy Garber, Vanesa Garcia-Barberan, Marion Gauthier-Villars, Andrea Gehrig, Anne-Marie Gerdes, Sophie Giraud, Andrew K Godwin, David E Goldgar, Christopher R Hake, Thomas V O Hansen, Sue Healey, Shirley Hodgson, Frans B L Hogervorst, Claude Houdayer, Peter J Hulick, Evgeny N Imyanitov, Claudine Isaacs, Louise Izatt, Angel Izquierdo, Lauren Jacobs, Anna Jakubowska, Ramunas Janavicius, Katarzyna Jaworska-Bieniek, Uffe Birk Jensen, Esther M John, Joseph Vijai, Beth Y Karlan, Karin Kast, KConFab Investigators, Sofia Khan, Ava Kwong, Yael Laitman, Jenny Lester, Fabienne Lesueur, Annelie Liljegren, Jan Lubinski, Phuong L Mai, Siranoush Manoukian, Sylvie Mazoyer, Alfons Meindl, Arjen R Mensenkamp, Marco Montagna, Katherine L Nathanson, Susan L Neuhausen, Heli Nevanlinna, Dieter Niederacher, Edith Olah, Olufunmilayo I Olopade, Kai-Ren Ong, Ana Osorio, Sue Kyung Park, Ylva Paulsson-Karlsson, Inge Sokilde Pedersen, Bernard Peissel, Paolo Peterlongo, Georg Pfeiler, Catherine M Phelan, Marion Piedmonte, Bruce Poppe, Miquel Angel Pujana, Paolo Radice, Gad Rennert, Gustavo C Rodriguez, Matti A Rookus, Eric A Ross, Rita Katharina Schmutzler, Jacques Simard, Christian F Singer, Thomas P Slavin, Penny Soucy, Melissa Southey, Doris Steinemann, Dominique Stoppa-Lyonnet, Grzegorz Sukiennicki, Christian Sutter, Csilla I Szabo, Muy-Kheng Tea, Manuel R Teixeira, Soo-Hwang Teo, Mary Beth Terry, Mads Thomassen, Maria Grazia Tibiletti, Laima Tihomirova, Silvia Tognazzo, Elizabeth J van Rensburg, Liliana Varesco, Raymonda Varon-Mateeva, Athanassios Vratimos, Jeffrey N Weitzel, Lesley McGuffog, Judy Kirk, Amanda Ewart Toland, Ute Hamann, Noralane Lindor, Susan J Ramus, Mark H Greene, Fergus J Couch, Kenneth Offit, Paul D P Pharoah, Georgia Chenevix-Trench, Antonis C Antoniou
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158801 (2016)
Population-based genome wide association studies have identified a locus at 9p22.2 associated with ovarian cancer risk, which also modifies ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. We conducted fine-scale mapping at 9p22.2 to identif
Externí odkaz:
https://doaj.org/article/3218667a15f94b26bb725ac2e8a2bbda
Autor:
Ava Kwong, Vivian Yvonne Shin, Cecilia Y. S. Ho, Chun Hang Au, Thomas P. Slavin, Jeffrey N. Weitzel, Tsun-Leung Chan, Edmond S. K. Ma
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the clinical implication for mutation carriers and their families is si
Externí odkaz:
https://doaj.org/article/00741944e70547149fff3695430a3e4a
Autor:
Mary B. Daly, Eric Rosenthal, Shelly Cummings, Ryan Bernhisel, John Kidd, Elisha Hughes, Alexander Gutin, Stephanie Meek, Thomas P. Slavin, Allison W. Kurian
Publikováno v:
Breast Cancer Research and Treatment. 199:617-626
Purpose Young age at breast cancer (BC) diagnosis and family history of BC are strongly associated with high prevalence of pathogenic variants (PVs) in BRCA1 and BRCA2 genes. There is limited evidence for such associations with moderate/high penetran
Autor:
Melanie A. Jones, Kirsten M. Timms, Shanell Hatcher, Elizabeth S. Cogan, Matthew S. Comeaux, Michael Perry, Brian Morris, Brad Swedlund, Cathy E. Elks, Pierre Lao‐Sirieix, Simon Dearden, Coumaran Egile, Jessica S. Brown, Elizabeth A. Harrington, Darren Hodgson, Matt Stern, Thomas P. Slavin, Debora Mancini‐DiNardo
Publikováno v:
Genes, Chromosomes and Cancer.
Autor:
Emad A. Rakha, Ian O. Ellis, Ralf Kronenwett, Jerry S. Lanchbury, Thomas P. Slavin, Alexander Gutin, Susanne Wagner, Jennifer Doedt, Vanessa Kuhl, Gabriella Savvidou, Ioanna Zouvani, Georgios Georgiou, Eleni Kakouri, Stephanie Meek, Braden Probst, Elisha Hughes, Ryan Bernhisel, Timothy Simmons, Michael S. Toss, Yiola Marcou, Anastasia Constantinidou
Supplementary Figure from Clinical Validation of EndoPredict in Pre-Menopausal Women with ER-Positive, HER2-Negative Primary Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39505d06a8de1caac6a15ca6417f5430
https://doi.org/10.1158/1078-0432.22489697.v1
https://doi.org/10.1158/1078-0432.22489697.v1
Autor:
Emad A. Rakha, Ian O. Ellis, Ralf Kronenwett, Jerry S. Lanchbury, Thomas P. Slavin, Alexander Gutin, Susanne Wagner, Jennifer Doedt, Vanessa Kuhl, Gabriella Savvidou, Ioanna Zouvani, Georgios Georgiou, Eleni Kakouri, Stephanie Meek, Braden Probst, Elisha Hughes, Ryan Bernhisel, Timothy Simmons, Michael S. Toss, Yiola Marcou, Anastasia Constantinidou
Supplementary Data from Clinical Validation of EndoPredict in Pre-Menopausal Women with ER-Positive, HER2-Negative Primary Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff343797b1c484d316d37f454558e17
https://doi.org/10.1158/1078-0432.22489700
https://doi.org/10.1158/1078-0432.22489700
Autor:
Emad A. Rakha, Ian O. Ellis, Ralf Kronenwett, Jerry S. Lanchbury, Thomas P. Slavin, Alexander Gutin, Susanne Wagner, Jennifer Doedt, Vanessa Kuhl, Gabriella Savvidou, Ioanna Zouvani, Georgios Georgiou, Eleni Kakouri, Stephanie Meek, Braden Probst, Elisha Hughes, Ryan Bernhisel, Timothy Simmons, Michael S. Toss, Yiola Marcou, Anastasia Constantinidou
Purpose:The EndoPredict prognostic assay is validated to predict distant recurrence and response to chemotherapy primarily in post-menopausal women with estrogen receptor–positive (ER+), HER2− breast cancer. This study evaluated the performance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6483347ee7e924d86df7c390a1eebe
https://doi.org/10.1158/1078-0432.c.6533012.v1
https://doi.org/10.1158/1078-0432.c.6533012.v1
Autor:
Kara N. Maxwell, Maureen E. Murphy, Raul C. Ribeiro, Gerard P. Zambetti, Richard W. Kriwacki, Sheri L. Spunt, Carolyn Fein Levy, Morris C. Edelman, Brooke Levin, Fergus J. Couch, Kelly McGoldrick, Stephanie Gutierrez, Jill S. Dolinsky, Kenneth Offit, Vijai Joseph, Judy E. Garber, Jill E. Stopfer, Jeffrey N. Weitzel, Thomas P. Slavin, Susan M. Domchek, Katherine L. Nathanson, Kristin Zelley, Louise C. Pyle, Suzanne P. MacFarland, Marilyn M. Li, Anh N. Le, Gregory Kelly, Ryan Hausler, Heena Desai, Aaron H. Philips, Andrew V. Kossenkov, Tetyana Martynyuk, Jessica C. Leung, Thibaut Barnoud, Emilia M. Pinto, Jacquelyn Powers
Supplementary Figures 1-4. Supplementary Figure S1: Full Pedigrees from TP53 c.1000G>C;p.G334R clinically ascertained families. Fam ID allows reference to Table 1; Supplementary Figure S2: Constructs encoding p53 wild-type (TP53-WT), p53-R175H (TP53-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c00e89c5b7cf956aea60439d2d5560
https://doi.org/10.1158/0008-5472.22425756
https://doi.org/10.1158/0008-5472.22425756
Autor:
Kara N. Maxwell, Maureen E. Murphy, Raul C. Ribeiro, Gerard P. Zambetti, Richard W. Kriwacki, Sheri L. Spunt, Carolyn Fein Levy, Morris C. Edelman, Brooke Levin, Fergus J. Couch, Kelly McGoldrick, Stephanie Gutierrez, Jill S. Dolinsky, Kenneth Offit, Vijai Joseph, Judy E. Garber, Jill E. Stopfer, Jeffrey N. Weitzel, Thomas P. Slavin, Susan M. Domchek, Katherine L. Nathanson, Kristin Zelley, Louise C. Pyle, Suzanne P. MacFarland, Marilyn M. Li, Anh N. Le, Gregory Kelly, Ryan Hausler, Heena Desai, Aaron H. Philips, Andrew V. Kossenkov, Tetyana Martynyuk, Jessica C. Leung, Thibaut Barnoud, Emilia M. Pinto, Jacquelyn Powers
Germline mutations in TP53 cause a rare high penetrance cancer syndrome, Li–Fraumeni syndrome (LFS). Here, we identified a rare TP53 tetramerization domain missense mutation, c.1000G>C;p.G334R, in a family with multiple late-onset LFS-spectrum canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b22083b0736e430d002f93b84e42e5
https://doi.org/10.1158/0008-5472.c.6512130
https://doi.org/10.1158/0008-5472.c.6512130
Autor:
Elisha Hughes, Ryan Bernhisel, Holly Pederson, Braden Probst, Timothy Simmons, Susanne Wagner, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M. Domchek, Charis Eng, Judy Garber, Monique Gary, Ora K. Gordon, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Funmi Olopade, Joseph Vijai, Jeffrey N. Weitzel, Pat Whitworth, Lamis Yehia, Allison Kurian, Mark Robson, Thomas P. Slavin, Alexander Gutin, Jerry S. Lanchbury
Publikováno v:
Cancer Research. 82:P2-11
Background: Polygenic risk scores (PRS) have been shown to provide genomically informed breast cancer risk assessment in both carriers and non-carriers of predisposing genetic mutations. Risk stratification is further improved by combining a PRS with