Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Thomas P Shanley"'
Autor:
Sarah J Atkinson, Natalie Z Cvijanovich, Neal J Thomas, Geoffrey L Allen, Nick Anas, Michael T Bigham, Mark Hall, Robert J Freishtat, Anita Sen, Keith Meyer, Paul A Checchia, Thomas P Shanley, Jeffrey Nowak, Michael Quasney, Scott L Weiss, Sharon Banschbach, Eileen Beckman, Kelli Howard, Erin Frank, Kelli Harmon, Patrick Lahni, Christopher J Lindsell, Hector R Wong
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112702 (2014)
The potential benefits of corticosteroids for septic shock may depend on initial mortality risk.We determined associations between corticosteroids and outcomes in children with septic shock who were stratified by initial mortality risk.We conducted a
Externí odkaz:
https://doaj.org/article/bb39686c858041eea69208a557425bc4
Autor:
Hector R Wong, Scott L Weiss, John S Giuliano, Mark S Wainwright, Natalie Z Cvijanovich, Neal J Thomas, Geoffrey L Allen, Nick Anas, Michael T Bigham, Mark Hall, Robert J Freishtat, Anita Sen, Keith Meyer, Paul A Checchia, Thomas P Shanley, Jeffrey Nowak, Michael Quasney, Arun Chopra, Julie C Fitzgerald, Rainer Gedeit, Sharon Banschbach, Eileen Beckman, Patrick Lahni, Kimberly Hart, Christopher J Lindsell
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86242 (2014)
We previously derived and validated a risk model to estimate mortality probability in children with septic shock (PERSEVERE; PEdiatRic SEpsis biomarkEr Risk modEl). PERSEVERE uses five biomarkers and age to estimate mortality probability. After the i
Externí odkaz:
https://doaj.org/article/fcf679b27aab4575978da2c417579828
Autor:
Hector R Wong, Scott L Weiss, John S Giuliano, Mark S Wainwright, Natalie Z Cvijanovich, Neal J Thomas, Geoffrey L Allen, Nick Anas, Michael T Bigham, Mark Hall, Robert J Freishtat, Anita Sen, Keith Meyer, Paul A Checchia, Thomas P Shanley, Jeffrey Nowak, Michael Quasney, Arun Chopra, Julie C Fitzgerald, Rainer Gedeit, Sharon Banschbach, Eileen Beckman, Kelli Harmon, Patrick Lahni, Christopher J Lindsell
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92121 (2014)
PERSEVERE is a risk model for estimating mortality probability in pediatric septic shock, using five biomarkers measured within 24 hours of clinical presentation.Here, we derive and test a temporal version of PERSEVERE (tPERSEVERE) that considers bio
Externí odkaz:
https://doaj.org/article/ca4073aaec724d39ba87d0fe09f8c3c3
Autor:
Dipankar Ray, Shirish Shukla, Uday Sankar Allam, Abigail Helman, Susmita Gurjar Ramanand, Linda Tran, Michael Bassetti, Pranathi Meda Krishnamurthy, Matthew Rumschlag, Michelle Paulsen, Lei Sun, Thomas P Shanley, Mats Ljungman, Mukesh K Nyati, Ming Zhang, Theodore S Lawrence
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57290 (2013)
The efficacy of radiation therapy for lung cancer is limited by radiation-induced lung toxicity (RILT). Although tumor necrosis factor-alpha (TNF-α) signaling plays a critical role in RILT, the molecular regulators of radiation-induced TNF-α produc
Externí odkaz:
https://doaj.org/article/3235ef109bed43da84dd15564da2bc50
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Microvascular endothelial hyperpermeability is an earliest pathological hallmark in Acute Lung Injury (ALI), which progressively leads to Acute Respiratory Distress Syndrome (ARDS). Recently, vascular protective and anti-inflammatory effe
Externí odkaz:
https://doaj.org/article/7cc0c4e37a174ce886376c6fd955ee56
Autor:
Erin F. Carlton, MD, MSc, Heidi M. Weeks, PhD, Mary K. Dahmer, PhD, Michael W. Quasney, MD, PhD, Anil Sapru, MD, MAS, Martha A.Q. Curley, PhD, RN, Heidi R. Flori, MD, for the BALI and RESTORE Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Heidi Flori, Michael W. Quasney, Mary K. Dahmer, Anil Sapru, Martha Curley, Michael A. Matthay, Scot T. Bateman, M. D. Berg, Santiago Borasino, G. Kris Bysani, Allison S. Cowl, Cindy Darnell Bowens, E. Vincent S. Faustino, Lori D. Fineman, A. J. Godshall, Ellie Hirshberg, Aileen L. Kirby, Gwenn E. McLaughlin, Shivanand Medar, Phineas P. Oren, James B. Schneider, Adam J. Schwarz, Thomas P. Shanley, Lauren R. Source, Edward J. Truemper, Michele A. Vander Heyden, Kim Wittmayer, Athena Zuppa, David Wypij, Martha A. Q. Curley, Geoffrey L. Allen, Derek C. Angus, Lisa A. Asaro, Judy A. Ascenzi, Ira M. Cheifetz, Brenda L. Dodson, Heidi R. Flori, Linda S. Franck, Rainer G. Gedeit, Mary Jo C. Grant, Andrea L. Harabin, Catherine Haskins-Kiefer, James H. Hertzog, Larissa Hutchins, Ruth M. Lebet, JoAnne E. Natale, Nagendra Polavarapu, Shari Simone, Lewis P. Singer, R. Scott Watson, Claire R. Wells
Publikováno v:
Critical Care Explorations, Vol 3, Iss 7, p e0467 (2021)
OBJECTIVES:. To evaluate the link between early acute respiratory failure and functional morbidity in survivors using the plasma biomarkers interleukin-8, interleukin-1 receptor antagonist, thrombomodulin, and plasminogen activator inhibitor-1. We hy
Externí odkaz:
https://doaj.org/article/61e7200c23f242228904d908a19129f5
Autor:
Nancy A. Calvin-Naylor, Carolynn Thomas Jones, Michelle M. Wartak, Karen Blackwell, Jonathan M. Davis, Ruthvick Divecha, Edward F. Ellerbeck, Karl Kieburtz, Margaret J. Koziel, Katherine Luzuriaga, Jennifer Maddox, Nancy A. Needler, Susan Murphy, Kieran Pemberton, Catherine Radovich, Eric P. Rubinstein, Harry P. Selker, Pamela Tenaerts, Kelly Unsworth, Kay Wilson, Jonelle E. Wright, Richard Barohn, Thomas P. Shanley
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 16-25 (2017)
Introduction Training for the clinical research workforce does not sufficiently prepare workers for today’s scientific complexity; deficiencies may be ameliorated with training. The Enhancing Clinical Research Professionals’ Training and Qualifi
Externí odkaz:
https://doaj.org/article/0a9996afaa3947ca968e65a222f3f1e5
Autor:
Thomas P. Shanley, Nancy A. Calvin-Naylor, Ruthvick Divecha, Michelle M. Wartak, Karen Blackwell, Jonathan M. Davis, Edward F. Ellerbeck, Karl Kieburtz, Margaret J. Koziel, Katherine Luzuriaga, Jennifer Maddox, Nancy A. Needler, Susan Murphy, Kieran Pemberton, Catherine Radovich, Eric P. Rubinstein, Harry P. Selker, Pamela Tenaerts, Kelly Unsworth, Kay Wilson, Jonelle E. Wright, Richard Barohn
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 8-15 (2017)
Introduction The translation of discoveries to drugs, devices, and behavioral interventions requires well-prepared study teams. Execution of clinical trials remains suboptimal due to varied quality in design, execution, analysis, and reporting. A cr
Externí odkaz:
https://doaj.org/article/36478c92f6344be3ad375e74d91b3a19
Autor:
Mary K Dahmer, Guangyu Yang, Min Zhang, Michael W Quasney, Anil Sapru, Heidi M Weeks, Pratik Sinha, Martha A Q Curley, Kevin L Delucchi, Carolyn S Calfee, Heidi Flori, Michael A Matthay, Scot T Bateman, Marc D Berg, Santiago Borasino, Gokul K Bysani, Allison S Cowl, Cindy D Bowens, Vincent S Faustino, Lori D Fineman, Aaron J Godshall, Eliotte L Hirshberg, Aileen L Kirby, Gwenn E McLaughlin, Shivanand S Medar, Phineas P Oren, James B Schneider, Adam J Schwarz, Thomas P Shanley, Lauren R Source, Edward J Truemper, Michele A Vender Heyden, Kimberly Wittmayer, Athena F Zuppa, David Wypij
Publikováno v:
Lancet Respir Med
Previous latent class analysis of adults with acute respiratory distress syndrome (ARDS) identified two phenotypes, distinguished by the degree of inflammation. We aimed to identify phenotypes in children with ARDS in whom developmental differences m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61437012754e24949aa17f7c99ea4dd
https://doi.org/10.1016/s2213-2600(21)00382-9
https://doi.org/10.1016/s2213-2600(21)00382-9
Autor:
JoAnne E. Natale, Lisa A. Asaro, Jill G. Joseph, Christine Ulysse, Judith Ascenzi, Cindy Bowens, David Wypij, Martha A. Q. Curley, Geoffrey L. Allen, Derek C. Angus, Judy A. Ascenzi, Scot T. Bateman, Santiago Borasino, Cindy Darnell Bowens, G. Kris Bysani, Ira M. Cheifetz, Allison S. Cowl, Brenda L. Dodson, E. Vincent S. Faustino, Lori D. Fineman, Heidi R. Flori, Linda S. Franck, Rainer G. Gedeit, Mary Jo C. Grant, Andrea L. Harabin, Catherine Haskins-Kiefer, James H. Hertzog, Larissa Hutchins, Aileen L. Kirby, Ruth M. Lebet, Michael A. Matthay, Gwenn E. McLaughlin, Phineas P. Oren, Nagendra Polavarapu, James B. Schneider, Adam J. Schwarz, Thomas P. Shanley, Shari Simone, Lewis P. Singer, Lauren R. Sorce, Edward J. Truemper, Michele A. Vander Heyden, R. Scott Watson, Claire R. Wells
Publikováno v:
Ann Am Thorac Soc
Rationale: Racial disparities in pain management have been previously reported for children receiving emergency care. Objectives: To determine whether patient race or ethnicity is associated with the broader goal of pain management and sedation among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4059c7b443f0b89f6b35297d7712656c
https://doi.org/10.1513/annalsats.201912-872oc
https://doi.org/10.1513/annalsats.201912-872oc