Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Thomas P Griener"'
Autor:
Thomas P Griener, Jonathan G Strecker, Romney M Humphries, George L Mulvey, Carmen Fuentealba, Robert E W Hancock, Glen D Armstrong
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21457 (2011)
Transgenic C57BL/6 mice expressing human serum amyloid P component (HuSAP) are resistant to Shiga toxin 2 (Stx2) at dosages that are lethal in HuSAP-negative wild-type mice. However, it is well established that Stx2 initiates extra-intestinal complic
Externí odkaz:
https://doaj.org/article/574a14306d43403eac36037931ff57d4
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Idiopathic CD4 lymphocytopenia (ICL) is a rare clinical disease with relative CD4 deficiency in the absence of HIV infection. The pathogenicity of ICL is poorly understood with an unclear incidence rate in the general population.
Externí odkaz:
https://doaj.org/article/416ca14b76e84dc2bd4edb4d203eb25a
Publikováno v:
Toxins, Vol 7, Iss 10, Pp 4054-4066 (2015)
Infection by Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) results in severe diarrhea, hemorrhagic colitis, and, occasionally, hemolytic-uremic syndrome (HUS). HUS is associated with an increase in pro-inflammatory cytokines a
Externí odkaz:
https://doaj.org/article/8169edec4f634782b77dd21aadde95cf
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-4 (2020)
BMC Infectious Diseases
BMC Infectious Diseases
Background Ureaplasma urealyticum is a fastidious bacteria which lacks a cell wall. Extragenital infections are rare in immunocompetent adults. There are few literature reports of perinephric abscess. We present a case of non-resolving multifocal “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62055b956f137fcba6ca0ce5f76a25a8
https://doaj.org/article/a989bc123cfa40d28c34b88abdbe1d0d
https://doaj.org/article/a989bc123cfa40d28c34b88abdbe1d0d
Autor:
Glen D. Armstrong, George L. Mulvey, Thomas P. Griener, Ravin Narain, Zhicheng Deng, Marya Ahmed, Joanna M. Sadowska, Eugenia Paszkiewicz, Pavel I. Kitov, David R. Bundle
Publikováno v:
Toxins, Vol 3, Iss 9, Pp 1065-1088 (2011)
Inhibition of AB5-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin’s pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid
Externí odkaz:
https://doaj.org/article/94a8a4f28d5f47108e25639e91613b18
BackgroundThis study evaluated the performance of a novel fast broad range PCR and sequencing (FBR-PCR/S) assay for the improved diagnosis of invasive fungal disease (IFD) in high-risk patients in a large Canadian healthcare region.MethodsA total of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41c279cbf96b886156c2b4bec7c9d390
https://doi.org/10.21203/rs.3.rs-1009236/v1
https://doi.org/10.21203/rs.3.rs-1009236/v1
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-5 (2019)
BMC Infectious Diseases
BMC Infectious Diseases
Background Idiopathic CD4 lymphocytopenia (ICL) is a rare clinical disease with relative CD4 deficiency in the absence of HIV infection. The pathogenicity of ICL is poorly understood with an unclear incidence rate in the general population. Sequelae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2617b84b6dcdba5d499e129bf1bec1
http://link.springer.com/article/10.1186/s12879-019-4453-x
http://link.springer.com/article/10.1186/s12879-019-4453-x
Autor:
Antoine Gürtler, Deirdre L. Church, Thomas P. Griener, Adrian M. Zelazny, Stefan Emler, Lorenzo Cerutti
Publikováno v:
Clin Microbiol Rev
This review provides a state-of-the-art description of the performance of Sanger cycle sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical microbiology laboratory. A detailed description of the technology and curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be729a5865243b6b4a920ce76eb4ca91
https://doi.org/10.1128/cmr.00053-19
https://doi.org/10.1128/cmr.00053-19
Autor:
Thomas P. Griener, Kanti Pabbaraju, Lisa Oberding, Markus Czub, Dylan R. Pillai, Guido van Marle, Keith R. Jerome, Venice Servellita, Cody Doolan, Byron M. Berenger, Luiz F. Lisboa, Charles Y. Chiu, Alexander L. Greninger, Jana Hundt, Abu Naser Mohon
Publikováno v:
Journal of Virological Methods
Highlights • The LAMP method performs equally to international reference RT-PCR methods for detection of SARS-CoV-2 • Experiments have been conducted that fulfil regulatory criteria by international bodies • LAMP as an LDT does not rely on RT-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c05a300c17355ac6b568a80f3b357c
http://europepmc.org/articles/PMC7490281
http://europepmc.org/articles/PMC7490281
Autor:
Jana Hundt, Dylan R. Pillai, Byron M. Berenger, Keith R. Jerome, Kanti Pabbaraju, Markus Czub, Alexander L. Greninger, Luiz F. Lisboa, Thomas P. Griener, Deirdre L. Church, Guido van Marle, Cody Doolan, Abu Naser Mohon
We have developed a reverse-transcriptase loop mediated amplification (RT-LAMP) method targeting genes encoding the Spike (S) protein and RNA-dependent RNA polymerase (RdRP) of SARS-CoV-2. The LAMP assay achieves comparable limit of detection as comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c0a6905658df48c2107d331a878f1a