Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Thomas P Flagg"'
Autor:
Naheed eFatima, Devin C Cohen, Gauthaman eSukumar, Tristan M Sissung, James F Schooley, Mark C Haigney, William C Claycomb, Rachel T Cox, Clifton Lee Dalgard, Susan E. Bates, Thomas P Flagg
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Histone deacetylase inhibitors (HDIs) are under investigation for the treatment of a number of human health problems. HDIs have proven therapeutic value in refractory cases of cutaneous T-cell lymphoma,. Electrocardiographic ST segment morphological
Externí odkaz:
https://doaj.org/article/cdcbb5a6778d4d39a2f73f2828104793
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41533 (2012)
Two mammalian genes encode the SURx (SUR1, Abcc8 and SUR2, Abcc9) subunits that combine with Kir6.2 (Kcnj11) subunits to form the ATP-sensitive potassium (KATP) channel in cardiac myocytes. Different isoform combinations endow the channel with distin
Externí odkaz:
https://doaj.org/article/bbbf5118523a4737ab347bef90ac45cc
Autor:
Michael G. Klein, Mori J. Krantz, Naheed Fatima, Ashlie Watters, Dayan Colon‐Sanchez, Robert M. Geiger, Robert E. Goldstein, Soroosh Solhjoo, Philip S. Mehler, Thomas P. Flagg, Mark C. Haigney
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 11 (2022)
Background Methadone is associated with a disproportionate risk of sudden death and ventricular tachyarrhythmia despite only modest inhibition of delayed rectifier K+ current (IKr), the principal mechanism of drug‐associated arrhythmia. Congenital
Externí odkaz:
https://doaj.org/article/4836ae533faf4cd6a1dc608576af254e
Autor:
Tanisha L. Currie, Marguerite M. Engler, Victor Krauthamer, Jonathan M. Scott, Patricia A. Deuster, Thomas P. Flagg
Publikováno v:
Nutrients, Vol 15, Iss 5, p 1204 (2023)
Optimal nutrition is imperative for psychological health. Oxidative stress and inflammation are underlying etiologies for alterations in psychological health. Warfighters are at risk of health concerns such as depression due to increased stress in au
Externí odkaz:
https://doaj.org/article/86921fc210184137ad0219ed37e84d97
Autor:
Narayanan Puthillathu Vasudevan, Dharmendra K. Soni, John R. Moffett, Jishnu K. S. Krishnan, Abhilash P. Appu, Sarani Ghoshal, Peethambaran Arun, John M. Denu, Thomas P. Flagg, Roopa Biswas, Aryan M. Namboodiri
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3673 (2023)
The coordination of cellular biological processes is regulated in part via metabolic enzymes acting to match cellular metabolism to current conditions. The acetate activating enzyme, acyl-coenzyme A synthetase short-chain family member 2 (Acss2), has
Externí odkaz:
https://doaj.org/article/8451fe2168cf47cca262190b2e9c5b03
Autor:
Susan E. Bates, Richard L. Piekarz, William D. Figg, Seth M. Steinberg, Mark C. Haigney, Thomas P. Flagg, David J. Venzon, Tristan M. Sissung, David J. Liewehr, Robin A. Eisch, Anne M. Noonan
Supplementary Figure 3 - PDF file 62K, Changes in mean heart rate during cycles 1 when patients taking betablockers were excluded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c09ac8e22e4be0770f1304d8a2f97f5
https://doi.org/10.1158/1078-0432.22450809.v1
https://doi.org/10.1158/1078-0432.22450809.v1
Autor:
Susan E. Bates, Richard L. Piekarz, William D. Figg, Seth M. Steinberg, Mark C. Haigney, Thomas P. Flagg, David J. Venzon, Tristan M. Sissung, David J. Liewehr, Robin A. Eisch, Anne M. Noonan
Supplementary Figure 4 - PDF file 314K, Changes in mean heart rate during cycles 1 when patients taking betablockers were excluded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ca3a593269b84acd02e0d8b5f58a7a
https://doi.org/10.1158/1078-0432.22450806.v1
https://doi.org/10.1158/1078-0432.22450806.v1
Autor:
Susan E. Bates, Richard L. Piekarz, William D. Figg, Seth M. Steinberg, Mark C. Haigney, Thomas P. Flagg, David J. Venzon, Tristan M. Sissung, David J. Liewehr, Robin A. Eisch, Anne M. Noonan
Supplementary Figure 6 - PDF file 60K, Changes in heart rate observed for each patient in the NIH cohort during cycle 2 days 1, 8 and 15, excluding the patients taking beta-blockers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ee3b87488980e69d40de4ba66736bc
https://doi.org/10.1158/1078-0432.22450800.v1
https://doi.org/10.1158/1078-0432.22450800.v1
Autor:
Susan E. Bates, Richard L. Piekarz, William D. Figg, Seth M. Steinberg, Mark C. Haigney, Thomas P. Flagg, David J. Venzon, Tristan M. Sissung, David J. Liewehr, Robin A. Eisch, Anne M. Noonan
Supplementary Figure Legends - PDF file 25K, Legends describing supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26983e175db6d2d1c0c9d409d03893c3
https://doi.org/10.1158/1078-0432.22450791
https://doi.org/10.1158/1078-0432.22450791
Autor:
Susan E. Bates, Richard L. Piekarz, William D. Figg, Seth M. Steinberg, Mark C. Haigney, Thomas P. Flagg, David J. Venzon, Tristan M. Sissung, David J. Liewehr, Robin A. Eisch, Anne M. Noonan
Supplemental Tables - PDF file 76K, Table S1. Diplotype arrangements of the ABCB1 SNPs calculated using Haploview. (Reproduced with authors' permission, Sissung et al, 2011(13); Table S2. Analysis of reported cardiovascular events for all 131 patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b702a414b6dbabb04e2c6711ac95d5
https://doi.org/10.1158/1078-0432.22450818
https://doi.org/10.1158/1078-0432.22450818