Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Thomas P C Dorlo"'
Autor:
Luka Verrest, Séverine Monnerat, Ahmed M Musa, Jane Mbui, Eltahir A G Khalil, Joseph Olobo, Monique Wasunna, Wan-Yu Chu, Alwin D R Huitema, Henk D F H Schallig, Fabiana Alves, Thomas P C Dorlo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012078 (2024)
BackgroundWith the current treatment options for visceral leishmaniasis (VL), recrudescence of the parasite is seen in a proportion of patients. Understanding parasite dynamics is crucial to improving treatment efficacy and predicting patient relapse
Externí odkaz:
https://doaj.org/article/f159d249ee9d4df7a72474193af8e333
Autor:
Brima Musa Younis, Ahmed Mudawi Musa, Séverine Monnerat, Mohammed Abdelrahim Saeed, Eltahir Awad Gasim Khalil, Anas Elbashir Ahmed, Mujahid Ahmed Ali, Ali Noureldin, Gina Muthoni Ouattara, Godfrey M Nyakaya, Samuel Teshome, Truphosa Omollo, Michael Ochieng, Thaddaeus Egondi, Mildred Mmbone, Wan-Yu Chu, Thomas P C Dorlo, Eduard E Zijlstra, Monique Wasunna, Jorge Alvar, Fabiana Alves
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011780 (2023)
BackgroundTreatment for post-kala-azar dermal leishmaniasis (PKDL) in Sudan is currently recommended only for patients with persistent or severe disease, mainly because of the limitations of current therapies, namely toxicity and long hospitalization
Externí odkaz:
https://doaj.org/article/8e80fbd2c0f14737b661e76f2ce1ecf5
Autor:
Monique Wasunna, Simon Njenga, Manica Balasegaram, Neal Alexander, Raymond Omollo, Tansy Edwards, Thomas P C Dorlo, Brima Musa, Mohammed Hassan Sharaf Ali, Mohammed Yasein Elamin, George Kirigi, Rashid Juma, Anke E Kip, Gerard J Schoone, Asrat Hailu, Joseph Olobo, Sally Ellis, Robert Kimutai, Susan Wells, Eltahir Awad Gasim Khalil, Nathalie Strub Wourgaft, Fabiana Alves, Ahmed Musa
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004880 (2016)
BACKGROUND:SSG&PM over 17 days is recommended as first line treatment for visceral leishmaniasis in eastern Africa, but is painful and requires hospitalization. Combination regimens including AmBisome and miltefosine are safe and effective in India,
Externí odkaz:
https://doaj.org/article/8f00c7ff8e114d8499c8306afaf2b491
Autor:
Thomas P C Dorlo, Manica Balasegaram
Publikováno v:
The Lancet Global Health, Vol 2, Iss 8, p e449 (2014)
Externí odkaz:
https://doaj.org/article/f8ed10666f424aa3958de52e18c011ca
Autor:
Bart Ostyn, Epco Hasker, Thomas P C Dorlo, Suman Rijal, Shyam Sundar, Jean-Claude Dujardin, Marleen Boelaert
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100220 (2014)
BACKGROUND:High frequency of relapse in miltefosine-treated visceral leishmaniasis (VL) patients in India and Nepal followed up for twelve months. OBJECTIVE:To identify epidemiological and clinical risk factors for relapse of VL in patients recently
Externí odkaz:
https://doaj.org/article/6a06d23b5fdd4ec48be488f5a156a449
Autor:
Eltahir A G Khalil, Teklu Weldegebreal, Brima M Younis, Raymond Omollo, Ahmed M Musa, Workagegnehu Hailu, Abuzaid A Abuzaid, Thomas P C Dorlo, Zewdu Hurissa, Sisay Yifru, William Haleke, Peter G Smith, Sally Ellis, Manica Balasegaram, Ahmed M EL-Hassan, Gerard J Schoone, Monique Wasunna, Robert Kimutai, Tansy Edwards, Asrat Hailu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 1, p e2613 (2014)
Anti-leishmanial drug regimens that include a single dose AmBisome could be suitable for eastern African patients with symptomatic visceral leishmaniasis (VL) but the appropriate single dose is unknown.A multi-centre, open-label, non-inferiority, ran
Externí odkaz:
https://doaj.org/article/0ca5beabc05445dca399343829a7a798
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 5, p e1544 (2012)
Externí odkaz:
https://doaj.org/article/9a048209b2ff4de1a1230b23cd6c50cb
Autor:
Thomas P C Dorlo, Pieter P A M van Thiel, Gerard J Schoone, Ymkje Stienstra, Michèle van Vugt, Jos H Beijnen, Peter J de Vries
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1436 (2011)
Parasite loads were quantified in repeated skin biopsies from lesions of 2 patients with Old-World cutaneous leishmaniasis (CL) caused by Leishmania major and L. infantum during and after treatment with miltefosine. Miltefosine induced a rapid therap
Externí odkaz:
https://doaj.org/article/1e84a8fb76c140d5a756cb98d074820f
Autor:
Thomas P C Dorlo, Piet A Kager
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 5, p e225 (2008)
Pentamidine has a long history in the treatment of human African trypanosomiasis (HAT) and leishmaniasis. Early guidelines on the dosage of pentamidine were based on the base-moiety of the two different formulations available. Confusion on the dosage
Externí odkaz:
https://doaj.org/article/a9c21b938f37499cab3ced370bc9ff24
Autor:
Ahmed M, Musa, Jane, Mbui, Rezika, Mohammed, Joseph, Olobo, Koert, Ritmeijer, Gabriel, Alcoba, Gina, Muthoni Ouattara, Thaddaeus, Egondi, Prossy, Nakanwagi, Truphosa, Omollo, Monique, Wasunna, Luka, Verrest, Thomas P C, Dorlo, Brima, Musa Younis, Ali, Nour, Elmukashfi, Taha Ahmed Elmukashfi, Ahmed, Ismail Omer Haroun, Eltahir A G, Khalil, Simon, Njenga, Helina, Fikre, Tigist, Mekonnen, Dagnew, Mersha, Kasaye, Sisay, Patrick, Sagaki, Jorge, Alvar, Alexandra, Solomos, Fabiana, Alves
Publikováno v:
Clinical Infectious Diseases. 76:e1177-e1185
Background This study aimed to determine whether paromomycin plus miltefosine (PM/MF) is noninferior to sodium stibogluconate plus paromomycin (SSG/PM) for treatment of primary visceral leishmaniasis in eastern Africa. Methods An open-label, phase 3,